MCDB 441 - Cell Biology and Disease
Fall 2022, Section 001
Instruction Mode: Section 001 is  In Person (see other Sections below)
Subject: Molecular, Cellular, and Developmental Biology (MCDB)
Department: LSA Molecular, Cellular, and Developmental Biology
See additional student enrollment and course instructor information to guide you in your decision making.


Requirements & Distribution:
With permission of instructor.
Advisory Prerequisites:
MCDB 428 and [MCDB 310 or MCDB 311 or BIOLCHEM 415 or CHEM 351].
This course counts toward the 60 credits of math/science required for a Bachelor of Science degree.
May not be repeated for credit.
Rackham Information:
Rackham credit requires additional work.
Primary Instructor:
Start/End Date:
Full Term 8/29/22 - 12/9/22 (see other Sections below)
NOTE: Drop/Add deadlines are dependent on the class meeting dates and will differ for full term versus partial term offerings.
For information on drop/add deadlines, see the Office of the Registrar and search Registration Deadlines.


This course will extend the basic knowledge of molecular cell biology into cellular disorders in human diseases. Selected topics on human diseases in which basic cell biological processes are defective will be explored in-depth using contemporary primary cell biology literature as the principal resource. An emphasis will be placed on the analysis of experimental design, methodology, and interpretation of data. A few lectures will be given to reinforce basic principles. Topics of investigation will include, but are not limited to, cellular defects in protein folding, targeting, and processing in neurodegenerative diseases such as Alzheimer’s disease; cell growth, cancer, and programmed cell death; cholesterol metabolism and atherosclerosis; insulin processing, secretion, and diabetes; and pathogen-cell interaction.

Course Requirements:

Grading will be based on class participation, quizzes, and presentations.

Intended Audience:

This course is intended for upper-level undergraduates and graduate students. It is appropriate for students interested in cell biology, biochemistry, molecular biology, pharmacology, and genetics.

Class Format:

The course will be comprised of paper readings, in-class discussions, presentations, and lectures. Participation is mandatory, student presentation is the major format of the course.


MCDB 441 - Cell Biology and Disease
Schedule Listing
001 (LEC)
 In Person
TuTh 4:00PM - 5:30PM
8/29/22 - 12/9/22

Textbooks/Other Materials

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Syllabi are available to current LSA students. IMPORTANT: These syllabi are provided to give students a general idea about the courses, as offered by LSA departments and programs in prior academic terms. The syllabi do not necessarily reflect the assignments, sequence of course materials, and/or course expectations that the faculty and departments/programs have for these same courses in the current and/or future terms.

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CourseProfile (Atlas)

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CourseProfile (Atlas)