The Art of Science - Single Molecule Fluorescence Illuminates Alzheimer’s


By sonyamcd
Mar 11, 2011 Bookmark and Share

The Art of Science - Single Molecule Fluorescence Illuminates Alzheimer’sTo showcase the artistic side of scientific imaging, Graduate Student Robin Johnson of the Gafni-Steel lab was selected to be in the top 10 of  the Biophysical Society's first-ever image contest, The Art of Science!  Her work was displayed in the Exhibit Hall for all to see.  The image above is a montage of TIRF images depicting the photobleaching of hundreds of single oligomers of fluorescently labeled amyloid-ß(1-40).  In the overlaid confocal image, single amyloid-ß(1-40) oligomers (black) decorate the DiO-labeled membranes of two SH-SY5Y cells; such aggregates may disrupt neuronal cell membrane integrity, contributing to the pathophysiology of Alzheimer’s disease.

Congratulations Robin!