Mar 11, 2011
To showcase the artistic side of scientific imaging, Graduate Student Robin Johnson of the Gafni-Steel lab was selected to be in the top 10 of the Biophysical Society's first-ever image contest, The Art of Science! Her work was displayed in the Exhibit Hall for all to see. The image above is a montage of TIRF images depicting the photobleaching of hundreds of single oligomers of fluorescently labeled amyloid-ß(1-40). In the overlaid confocal image, single amyloid-ß(1-40) oligomers (black) decorate the DiO-labeled membranes of two SH-SY5Y cells; such aggregates may disrupt neuronal cell membrane integrity, contributing to the pathophysiology of Alzheimer’s disease.