This course provides a basic introduction to the neuropsychopharmacology of drug abuse and addiction, and has a strong natural science (neuroscience) orientation. The acute and long-term effects of selected drugs of abuse on behavior, mood, cognition, and neuronal function are discussed, and material from studies with humans is integrated with basic studies on the neurobiological basis of drug action and drug abuse — including detailed coverage of synaptic transmission and the distribution, regulation, and integration of brain neurotransmitter systems. The focus is on addictive or illicit drugs, and all the major classes are discussed, including: opiates (heroin, morphine, opium), sedative-hypnotics (alcohol, barbituates, chloral hydrate), anxiolytics (benzodiazepines), psychomotor stimulants (amphetamine, cocaine), marijuana, hallucinogens (LSD, mescaline), hallucinogenic-stimulants (MDA, MDMA), and dissociative anaesthetics (PCP). A lecture format is used, with required readings from a text. The course is intended primarily for juniors or seniors concentrating in biopsychology, biology, or the biomedical sciences (e.g., pre-med). Required Text: JS Meyer and LF Quenzer, Psychopharmacology: Drugs, the Brain and Behavior, 2005. Exams and Grading: The course grade will be based on the outcome of three multiple choice/short answer type exams.