ENGR 100 - Intro Engineering
Section: 500 Biotechnology and Human Values
Term: FA 2008
Subject: Engineering (ENGR)
Department: CoE Undergraduate Education
Credits:
4 (Non-LSA credit).
Consent:
With permission of department.
Advisory Prerequisites:
ENGIN.
Other Course Info:
(Non-LSA). F, W.
Repeatability:
May not be repeated for credit.
Primary Instructor:
Instructor:

Biotechnology combines the engineering principles of analysis, design, and optimization with the tools of cellular and molecular biology. It impacts nearly every aspect of our daily lives, from the food we eat to the medicine we take. The primary purpose of this course is to teach a basic vocabulary in biotechnology and expose students to the breadth of biotechnology and its impact on our daily lives. Topics will cover a broad range of applications in genetics, molecular diagnostics, molecular imaging, and clinical devices. A key additional component will be to investigate human values issues, such as ethical questions and cost effectiveness, arising from these technologies. Teamwork in the lab and through an independent project is emphasized. Report writing and presentations are required throughout the term, culminating with a final report and public presentation.

Welcome! This course brings together students in the life sciences and engineering to explore basic issues facing biotechnologists. In addition to introducing basic sciences, this course will explore some of the dominant trends in biotechnology, not only in terms of their scientific and technological impact, but also in terms of their implications for human values. Our objective is to provide you with the real life challenge of designing a solution for a client and allow you to experience the complex dynamics that govern the design process in the interdisciplinary field of Biotechnology.

The Lab
Unique to this course are two hands-on labs: DNA analysis and molecular imaging. These labs will allow you to assess the efficacy and feasibility of existing technologies, as well as explore their suitability for a spectrum of social, political, and economic realities.

The Project
As another unique opportunity of this course, you will conduct an investigative study for a real client, the University of Michigan School of Medicine. Your project will consist of designing a test capable of detecting hereditary disease before the onset of symptoms. You will be assigned to a project team, which, in turn, will be assigned to a client physician. Your team will collaborate with the physician to determine how the prognosis of a target disease could benefit from genetic testing. This will require research into the genetics of the target disease, the disease process, treatments, and evaluation of the potential impact of early detection for the individual patient, health care management, and society at large. Given the needs of the patient and physicians, you will draw on your research and lab experiences to determine the most useful and appropriate methods for pre-symptom testing. This will require a quantitative, as well as qualitative, evaluation of your proposed technology and its effect on disease outcome, health care delivery, and patient quality of life.

Course Organization and Resources
This course is conducted by a multi-disciplinary team of instructors led by Professor Matthew O'Donnell. Your time in the classroom will be divided into biweekly lectures, a weekly lab and a weekly discussion section. In addition, each team will meet periodically with instructors in scheduled workshops held during evening hours. Deliverables will consist of technical assignments, lab reports, oral presentations, and a final formal oral presentation and report for our clients and other interested parties.

In this course, we rely heavily on independent study, instructor-student interaction, and on-line resources. Topics addressed include microbiology, gene sequencing and expression, testing technology, statistics, ethics, legal issues, team management, technical communications, problem-solving strategies, and the design process. We conduct on-line discussions and provide a wealth of resources via our course website.

This course is highly challenging and demanding, and our expectations are high. However, students who take the challenge seriously have the opportunity to experience that sense of achievement that comes from meeting and even exceeding their own expectations. For students interested in pursuing a degree in cellular and molecular biology, biotechnology, or biomedical engineering, this course is a must. Join us. We look forward to another high-powered semester.

ENGR 100 - Intro Engineering
Schedule Listing
100 (LEC)
 
10704
Open
1
 
-
TuTh 2:30PM - 4:00PM
Note: STUDENTS ELECTING DIS (101-104) WILL BE AUTO-ENROLLED IN LEC 100.
101 (DIS)
P
10705
Closed
0
 
-
TuTh 12:30PM - 1:30PM
102 (DIS)
P
10706
Closed
0
 
-
TuTh 1:30PM - 2:30PM
103 (DIS)
P
10707
Open
1
 
-
TuTh 12:30PM - 1:30PM
104 (DIS)
P
10708
Closed
0
 
-
TuTh 1:30PM - 2:30PM
200 (LEC)
 
10709
Closed
0
 
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TuTh 9:00AM - 10:30AM
Note: STUDENTS ELECTING DIS (201-206) WILL BE AUTO-ENROLLED IN LEC 200.
201 (DIS)
P
10710
Closed
0
 
-
TuTh 10:30AM - 11:30AM
202 (DIS)
P
10711
Closed
0
 
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TuTh 11:30AM - 12:30PM
203 (DIS)
P
10712
Closed
0
 
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TuTh 10:30AM - 11:30AM
204 (DIS)
P
10713
Closed
0
 
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TuTh 11:30AM - 12:30PM
205 (DIS)
P
20474
Closed
0
 
-
TuTh 12:30PM - 1:30PM
300 (LEC)
 
10714
Open
5
 
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TuTh 10:30AM - 12:00PM
Note: STUDENTS ELECTING DIS (301-304) WILL BE AUTO-ENROLLED IN LEC 300.
301 (DIS)
P
10715
Closed
0
 
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Th 12:30PM - 1:30PM
Th 1:30PM - 3:30PM
Note: Please note: Labs take place in Pierpoint B521 on Thursdays 1:30-3:30pm
302 (DIS)
P
10716
Open
5
 
-
Tu 12:30PM - 1:30PM
Tu 1:30PM - 3:30PM
Note: Please note: Labs take place in Pierpoint B521 on Tuesdays 1:30-3:30pm
400 (LEC)
 
10719
Open
1
 
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MW 3:30PM - 5:30PM
Note: STUDENTS ELECTING DIS (401-404) WILL BE AUTO-ENROLLED IN LEC 400.
401 (DIS)
P
10720
Closed
0
 
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F 3:30PM - 4:30PM
402 (DIS)
P
10721
Open
1
 
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F 4:30PM - 5:30PM
403 (DIS)
P
10722
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0
 
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F 3:30PM - 4:30PM
404 (DIS)
P
10723
Closed
0
 
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F 4:30PM - 5:30PM
500 (LEC)
 
10724
Open
31
 
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TuTh 1:30PM - 3:00PM
Note: STUDENTS ELECTING DIS (501-504) WILL BE AUTO-ENROLLED IN LEC 500.
501 (DIS)
P
10725
Open
7
 
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TuTh 11:30AM - 12:30PM
502 (DIS)
P
10726
Open
9
 
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TuTh 12:30PM - 1:30PM
503 (DIS)
P
10727
Open
5
 
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TuTh 11:30AM - 12:30PM
504 (DIS)
P
10728
Open
10
 
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TuTh 12:30PM - 1:30PM
600 (LEC)
 
23382
Closed
0
 
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MW 1:30PM - 2:30PM
Note: STUDENTS ELECTING DIS (601-604) WILL BE AUTO-ENROLLED IN LEC 600.
601 (DIS)
P
23383
Closed
0
 
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Th 10:30AM - 12:30PM
Tu 10:30AM - 12:00PM
602 (DIS)
P
23384
Closed
0
 
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Tu 8:30AM - 10:30AM
W 10:30AM - 12:00PM
603 (DIS)
P
23385
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0
 
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Tu 10:30AM - 12:30PM
Th 10:30AM - 12:00PM
604 (DIS)
P
23386
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0
 
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W 10:30AM - 12:30PM
F 10:30AM - 12:00PM
700 (LEC)
 
21563
Closed
0
 
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TuTh 8:00AM - 9:30AM
Note: STUDENTS ELECTING DIS (701-704) WILL BE AUTO-ENROLLED IN LEC 700.
701 (DIS)
P
21564
Closed
0
 
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Tu 10:00AM - 12:00PM
Tu 12:00PM - 1:00PM
702 (DIS)
P
21565
Closed
0
 
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Tu 1:30PM - 3:30PM
Tu 3:30PM - 4:30PM
703 (DIS)
P
21566
Closed
0
 
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Th 10:00AM - 12:00PM
Th 12:00PM - 1:00PM
704 (DIS)
P
22662
Closed
0
 
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Th 1:30PM - 3:30PM
Th 3:30PM - 4:30PM
800 (LEC)
 
23387
Open
1
 
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MW 12:00PM - 1:30PM
Note: STUDENTS ELECTING DIS (801-803) WILL BE AUTO-ENROLLED IN LEC 800. PLEASE NOTE: SECTIONS 801-803 HAVE TWO MEETING PATTERNS.
801 (DIS)
P
23388
Closed
0
 
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MW 1:30PM - 2:30PM
802 (DIS)
P
23389
Closed
0
 
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MW 2:30PM - 3:30PM
803 (DIS)
P
23390
Open
2
 
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MW 3:30PM - 4:30PM
900 (LEC)
 
26271
Open
1
 
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MW 8:00AM - 9:30AM
Note: STUDENTS ELECTING DIS (901-904) WILL BE AUTO-ENROLLED IN LEC 900
901 (DIS)
P
26272
Closed
0
 
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M 10:00AM - 12:00PM
M 12:00PM - 1:00PM
902 (DIS)
P
26273
Closed
0
 
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M 2:30PM - 4:30PM
M 4:30PM - 5:30PM
903 (DIS)
P
26274
Open
1
1ENGR Fr
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W 10:00AM - 12:00PM
W 12:00PM - 1:00PM
904 (DIS)
P
23938
Open
1
 
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W 1:30PM - 3:30PM
W 3:30PM - 4:30PM
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