BIOLCHEM 673 - Kinetics and Mechanism
Section: 001
Term: WN 2010
Subject: Biological Chemistry (BIOLCHEM)
Department: MED Biological Chemistry
Requirements & Distribution:
Waitlist Capacity:
Advisory Prerequisites:
BIOLCHEM 550, CHEMBIO 501, or equivalent, undergrad calculus. Physical Chemistry is recommended.
This course counts toward the 60 credits of math/science required for a Bachelor of Science degree.
May not be repeated for credit.
Primary Instructor:

This course will cover the investigation of enzyme mechanisms with an emphasis on kinetic and thermodynamic methodology, including: ligand binding to macromolecules, transient kinetics, steady-state kinetics, and kinetic isotope effects. The key kinetic and thermodynamic concepts that govern the action of enzymes, and the thought processes required to deduce catalytic and kinetic mechanisms will be explored. Topics will be treated from both a "gut-feeling" and a mathematical perspective, and applications to real systems, including experimental methods, data analysis, and common errors/fallacies/abuses, will be considered in detail. Because computer methods for analyzing and simulating data have taken a prominent place in the field, the use of software from kinetics research will be emphasized through numerous "hands-on" exercises.

BIOLCHEM 673 - Kinetics and Mechanism
Schedule Listing
001 (LEC)
MWF 10:00AM - 11:00AM
Note: Class meets Jan 6-Feb 26, 2010.
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