MCDB 456 - Genes, Circuits, and Behavior
Section: 001
Term: FA 2010
Subject: Molecular, Cellular, and Developmental Biology (MCDB)
Department: LSA Molecular, Cellular, and Developmental Biology
Requirements & Distribution:
Waitlist Capacity:
Enforced Prerequisites:
Advisory Prerequisites:
MCDB 310 or BIOLCHEM 415 or CHEM 351.
This course counts toward the 60 credits of math/science required for a Bachelor of Science degree.
May not be repeated for credit.
Rackham Information:
Rackham credit requires additional work.
Primary Instructor:

Newly developed methods in genetics, live-imaging, and neuro-informatics are rapidly expanding our understanding of how genetically defined neural circuits function within the nervous system. In genetically tractable model systems, both vertebrate and invertebrate, it is now possible to address the ways in which gene function, neural connectivity, and neurophysiology cooperate to determine overt animal behavior. This course provides students with an in-depth introduction to the neurobiology of model organisms that have made significant contributions toward a mechanistic understanding of brain function and behavior. Readings are from both the modern primary literature and from seminal works of model system neuroscience. This course explores the neuronal and genetic basis of a wide range of behaviors, including but not limited to feeding behavior, learning and memory, sensory perception, sleep, and circadian rhythms. The genetic basis of these behaviors will be discussed and recent experimental work concerning the anatomical and physiological control of these same behaviors will be investigated via class discussions and student presentations. Based on recently published results, students will form new hypotheses and propose strategies for testing them. Particular focus will be placed on experimental design and interpretation of data.

Course requirements include weekly written assignments, class participation, a research proposal, and a group class presentation. Students will be evaluated predominantly based on the quality of their written work (weekly assignments and research proposal), class presentation, and, to a somewhat lesser extent, on the degree to which they engage in class discussion. Students will discuss and debate data from the primary literature and be asked to propose new or improved experimental approaches to modern problems in neuroscience. They will be asked to write new proposals based on work discussed in class.

This course is intended for upper-level Biology, CMB, and Neuroscience concentrators, and first-year graduate students.

The class will have two ninety-minute weekly meetings. There will be a mixture of lecture, discussion, and student participation.

MCDB 456 - Genes, Circuits, and Behavior
Schedule Listing
001 (LEC)
MW 2:30PM - 4:00PM
NOTE: Data maintained by department in Wolverine Access. If no textbooks are listed below, check with the department.
Syllabi are available to current LSA students. IMPORTANT: These syllabi are provided to give students a general idea about the courses, as offered by LSA departments and programs in prior academic terms. The syllabi do not necessarily reflect the assignments, sequence of course materials, and/or course expectations that the faculty and departments/programs have for these same courses in the current and/or future terms.

Click the button below to view historical syllabi for MCDB 456 (UM login required)

View Historical Syllabi
The CourseProfile (ART) system, supported by the U-M Provost’s 3rd Century Initiative through a grant to the Office of Academic Innovation, provides additional information about: course enrollments; academic terms and instructors; student academic profiles (school/college, majors), and previous, concurrent, and subsequent course enrollments.

CourseProfile (ART)