Music and physics have a long history together. Each has influenced the other since the dawn of history. We will take a holistic look at this symbiotic historical relationship. Along the way we will learn about many beautiful phenomena of nature, how these phenomena are understood using the scientific method, and how they manifest in the working of musical instruments, in auditorium acoustics, in devices for sound recording and reproduction, and in the human voice, human hearing, and human perception of sound. The concepts of the course will be presented through textbook readings, lectures with demonstration experiments, and homework exercises. No previous expertise in either physics or music is required.