MCDB 423 - Introduction to Research in Cellular and Molecular Neurobiology
Winter 2018, Section 002
Instruction Mode: Section 002 is (see other Sections below)
Subject: Molecular, Cellular, and Developmental Biology (MCDB)
Department: LSA Molecular, Cellular, and Developmental Biology


Requirements & Distribution:
With permission of instructor.
Lab Fee:
Enforced Prerequisites:
Advisory Prerequisites:
BIOLOGY 225 or BIOLOGY 222; or concurrent enrollment in MCDB 422.
Other Course Info:
F and W. Satisfies a Biology laboratory requirement.
This course counts toward the 60 credits of math/science required for a Bachelor of Science degree.
May not be repeated for credit.
Primary Instructor:


This lab course provides an introduction to experimental approaches in neurobiology. Emphasis is on molecular, physiological and anatomical approaches for studying neuronal function. Students will learn how to introduce a single amino acid mutation within a neuronal receptor, make mutant DNA, mutant RNA and then study the function of the mutated receptor. Several other molecular biology techniques such as western blotting, RTPCR are also performed. The function of different neuronal receptors is studied through electrophysiology recording and fluorescent microscopy. Among the anatomical topics to be covered are gross and microscopic anatomy of nervous systems, axonal pathway tracing, and immunocytochemical localization of specific neuronal proteins. For data acquisition and data analysis, student will learn how to use software such as Pclamp and Image J. Textbook: Students will need to purchase a lab manual, which is available at one of the bookstores.

Course Requirements:

Grades are based on several discussions/presentations, quizzes, an organized lab notebook and two exams.

Intended Audience:

This lab course can be used to satisfy requirements for the neuroscience concentration, the Cell and Molecular Biology Concentration and the Biology Concentration.

Class Format:

The eight hours per week are organized into prep lectures, lab sessions and discussion sessions. Prep lectures are used to introduce methodology and techniques performed in the lab, lab sessions are used to carry out experiments and discussion sessions are used to present and discuss results.


MCDB 423 - Introduction to Research in Cellular and Molecular Neurobiology
Schedule Listing
001 (LAB)
 In Person
MW 12:00PM - 4:00PM
002 (LAB)
 In Person
TuTh 12:00PM - 4:00PM

Textbooks/Other Materials

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Syllabi are available to current LSA students. IMPORTANT: These syllabi are provided to give students a general idea about the courses, as offered by LSA departments and programs in prior academic terms. The syllabi do not necessarily reflect the assignments, sequence of course materials, and/or course expectations that the faculty and departments/programs have for these same courses in the current and/or future terms.

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