MEDCHEM 528 - Biology and Chemistry of Enzymes
Section: 001
Term: WN 2018
Subject: Medicinal Chemistry (MEDCHEM)
Department: College of Pharmacy
Credits:
2
Requirements & Distribution:
BS
Waitlist Capacity:
10
Advisory Prerequisites:
BIOLCHEM 550, CHEMBIO 501 or equivalent, and one semester of Organic Chemistry.
BS:
This course counts toward the 60 credits of math/science required for a Bachelor of Science degree.
Repeatability:
May not be repeated for credit.
Primary Instructor:

This course will explore the roles of organic and organometallic cofactors in biology. Topics covered will be cofactor assembly, cofactors as sensors, and cofactors in enzyme chemistry, with an emphasis on modulation of cofactor reactivity by complexation with the protein. The lectures will be complemented by assigned reading material from the primary literature and will assume basic familiarity with bioorganic chemistry. One guest lecturer will be included in the sequence.

MEDCHEM 528 - Biology and Chemistry of Enzymes
Schedule Listing
001 (LEC)
P
20534
Open
40
 
-
MWF 10:00AM - 11:00AM
Note: This course meets for the first half of the term: 1/8/13 - 2/24/14.
NOTE: Data maintained by department in Wolverine Access. If no textbooks are listed below, check with the department.


ISBN: 0716716143
Enzyme structure and mechanism, Author: Alan Fersht., Publisher: W.H. Freeman 2nd ed. 1985
Optional
ISBN: 9780195122589
Enzymatic reaction mechanisms, Author: Perry A. Frey and Adrian D. Hegeman., Publisher: Oxford University Press 2006
Optional
ISBN: 9780126437317
The organic chemistry of enzyme-catalyzed reactions, Author: Richard B. Silverman., Publisher: Acad. Press Rev. ed. 2002
Optional
ISBN: 9780470570951
Biochemistry, Author: Donald Voet, Judith G. Voet., Publisher: John Wiley & Sons 4th ed. 2011
Optional
Syllabi are available to current LSA students. IMPORTANT: These syllabi are provided to give students a general idea about the courses, as offered by LSA departments and programs in prior academic terms. The syllabi do not necessarily reflect the assignments, sequence of course materials, and/or course expectations that the faculty and departments/programs have for these same courses in the current and/or future terms.

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