BIOPHYS 370 - Physical and Chemical Principles Behind Biology and Medicine
Section: 001
Term: FA 2018
Subject: Biophysics (BIOPHYS)
Department: LSA Biophysics
Requirements & Distribution:
Credit Exclusions:
No credit granted to students who have completed or are enrolled in CHEM 260 or PHYSICS 390.
Waitlist Capacity:
Enforced Prerequisites:
MATH 215; and PHYSICS 235 or 240.
Advisory Prerequisites:
CHEM 130 or placement in 210.
This course counts toward the 60 credits of math/science required for a Bachelor of Science degree.
May not be repeated for credit.
Primary Instructor:

Physical chemistry is having a major impact on all areas of science that concern the properties of molecules. In particular, the design of pharmaceutical drugs, understanding detailed structure-function relationships of proteins, RNA and DNA are highly dependent on the development of physical chemistry concepts.

This course introduces students to physical chemistry (and to the pioneers of these theories) using a biomolecular approach. The underlying principles of quantum mechanics are covered first and then utilized to understand the basic principles of spectroscopy (electronic, vibrational, rotational and magnetic resonance) and other quantum phenomena such as electron/proton tunneling in enzymes. Molecular orbital calculations that can be completed with pencil and paper on simple organic molecules are also covered, giving students a view of theoretical chemistry.

Armed with the tools of quantum chemistry, students shall learn that the laws of thermodynamics can be formulated in terms of the properties of atoms and molecules that make up macroscopic systems. Students will then utilize these concepts to understand the workings of (bio)molecular machines. Mathematical topics are reviewed before using them to develop biophysical chemistry concepts.

The outcome of this course will provide students with the ability to understand research problems in biotechnology and medical fields from a physical chemistry perspective.

Course Requirements:

Examinations, participation in Biophysics seminars, homework assignments and a special final project.

Intended Audience:

Biophysics majors at the junior level and other students interested in Biophysics, Biochemistry, Chemistry, Physics, and Engineering.

Class Format:

Three hours per week in a lecture format with weekly one-hour discussions led by a GSI.

BIOPHYS 370 - Physical and Chemical Principles Behind Biology and Medicine
Schedule Listing
001 (LEC)
TuTh 11:30AM - 1:00PM
NOTE: Data maintained by department in Wolverine Access. If no textbooks are listed below, check with the department.

ISBN: 9780199564286
Physical chemistry for the life sciences, Author: Peter Atkins; Julio de Paula., Publisher: Oxford University Press 2. ed. 2011
ISBN: 9780815344308
Molecular driving forces, Author: by Ken Dill, Sarina Bromberg., Publisher: Garland Science 2nd ed. 2010
Syllabi are available to current LSA students. IMPORTANT: These syllabi are provided to give students a general idea about the courses, as offered by LSA departments and programs in prior academic terms. The syllabi do not necessarily reflect the assignments, sequence of course materials, and/or course expectations that the faculty and departments/programs have for these same courses in the current and/or future terms.

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