HUMGEN 541 - Molecular Genetics
Section: 001
Term: FA 2018
Subject: Human Genetics (HUMGEN)
Department: MED Human Genetics
3 (Non-LSA credit).
Requirements & Distribution:
Waitlist Capacity:
Advisory Prerequisites:
An undergraduate-level course in general biology is required, a specialized undergraduate-level course in genetics (e.g. BIOLOGY 305) is strongly recommended.
This course counts toward the 60 credits of math/science required for a Bachelor of Science degree.
May not be repeated for credit.
Primary Instructor:

A combination of classic and current papers in molecular genetics will be selected to accompany the lecture material (1-2 papers per lecture). The foundations of modern genetics will launch the course, including both the fundamentals and current research methods for analysis of gene structure and gene expression. The gene expression component will include positive and negative regulation of transcription, and mRNA splicing and turnover. The basics of DNA recombination, repair and transposition will be covered in relationship to cancer, evolution and mutagenesis. Strategies for developmental regulation will be presented. Parallels between prokaryotes and eukaryotes will be drawn, and comparisons will be made between the temporal and spatial control of gene expression in vertebrates and invertebrates. Genetic engineering topics will include gene targeting and transgenesis, with applications to understanding tissue specific control of gene expression. The course will close with discussion of the Genome Project, identification of disease genes and an introduction to the medical application of molecular genetics including gene therapy.

HUMGEN 541 - Molecular Genetics
Schedule Listing
001 (LEC)
MWF 9:00AM - 10:00AM
Note: Recitations on Mondays from 5:00-6:00 pm and on Tuesdays from 12:00-1:00 pm. Optional for students.
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