MCDB 421 - Topics in Cellular and Molecular Neurobiology
Section: 001 Cellular Diversity in the Immune and Nervous Systems
Term: FA 2018
Subject: Molecular, Cellular, and Developmental Biology (MCDB)
Department: LSA Molecular, Cellular, and Developmental Biology
Requirements & Distribution:
With permission of instructor.
Advisory Prerequisites:
BIOLOGY 225 and PSYCH 230 or NEUROSCI 601.
This course counts toward the 60 credits of math/science required for a Bachelor of Science degree.
May be elected twice for credit. May be elected more than once in the same term.
Rackham Information:
Rackham credit requires additional work.
Primary Instructor:

In traditional video games, like Grand Theft Auto, the entire world in which the game is played is explicitly coded. However, games like Rogue, Minecraft, and No Man’s Sky generate different worlds each time the game is played by supplying relatively simple world-generating algorithms with random numbers. While the development of biological organisms appears to follow an explicit set of genomic instructions to generate the same outcome each time, like Grand Theft Auto, many biological mechanisms harness molecular noise to produce variable outcomes, like Rogue. This is particularly evident in the immune system, where random recombination produces millions of antibodies from only a few genes, and in the nervous system, where stochastic mechanisms vary the sensory receptors and synaptic matching molecules produced by different neurons. This course will focus on the stochastic genetic and molecular mechanisms that produce cellular variety in the immune and nervous systems, with an emphasis on the primary literature.

MCDB 421 - Topics in Cellular and Molecular Neurobiology
Schedule Listing
001 (LEC)
MW 4:00PM - 5:30PM
Note: Prerequisites for the course are either Bio 305 or MCDB 310 or by permission of instructor. A background in Neuroscience is not required.
NOTE: Data maintained by department in Wolverine Access. If no textbooks are listed below, check with the department.
Syllabi are available to current LSA students. IMPORTANT: These syllabi are provided to give students a general idea about the courses, as offered by LSA departments and programs in prior academic terms. The syllabi do not necessarily reflect the assignments, sequence of course materials, and/or course expectations that the faculty and departments/programs have for these same courses in the current and/or future terms.

Click the button below to view historical syllabi for MCDB 421 (UM login required)

View Historical Syllabi
The CourseProfile (ART) system, supported by the U-M Provost’s 3rd Century Initiative through a grant to the Office of Academic Innovation, provides additional information about: course enrollments; academic terms and instructors; student academic profiles (school/college, majors), and previous, concurrent, and subsequent course enrollments.

CourseProfile (ART)