BIOPHYS 421 - Structural Biology: Biophysical Controversies
Fall 2020, Section 002
Instruction Mode: Section 002 is  Online (see other Sections below)
Subject: Biophysics (BIOPHYS)
Department: LSA Biophysics
See additional student enrollment and course instructor information to guide you in your decision making.


Requirements & Distribution:
Advisory Prerequisites:
Previous or concurrent enrollment in CHEM 351, MCDB 310, or BIOLCHEM 415.
This course counts toward the 60 credits of math/science required for a Bachelor of Science degree.
May not be repeated for credit.
Primary Instructor:


This course aims to address scientific controversies in structural biology through a discussion-based process. Additionally, students will be introduced to major structural biological determination techniques. Strengths and weaknesses of these techniques will be explored in the primary literature, and students will examine how to avoid the pitfalls of their misuse.

Some of the specific topics to be covered in this course are:

  • Biophysical approaches for structural studies
  • Roles of biomolecular structures in various diseases
  • Latest breakthroughs in structural biology
  • Better understanding of biological function from structure and dynamics
  • In-depth learning from controversial scientific findings
  • Development of scientific presentation skills

Course Requirements:

There are no exams in this course. There will be some quiz questions for this course that will be asynchronous and will consist of short answer and essay questions that will be submitted via Canvas during a designated time frame. Moreover journal club presentations will be graded by the students based on a rubric that will be provided to them. These grades will be submitted directly to the instructor by email and I will import them in Canvas. Moreover special assignments will be provided that will be graded asynchronously.

Lectures for this course will be recorded and made available asynchronously. We will also hold discussion sessions and student journal club presentations that require synchronous participation through Zoom.

Class Format:

This course will be offered in hybrid format. This course welcomes entirely online participation. While there will be optional in-person components, no part of this course requires you to be on campus or present in-person. The lectures for this course can be recorded and made available asynchronously. We will also have weekly discussion sessions and student journal club presentations that require synchronous participation through Zoom.


BIOPHYS 421 - Structural Biology: Biophysical Controversies
Schedule Listing
001 (LEC)
TuTh 1:00PM - 2:30PM
002 (LEC)
TuTh 1:00PM - 2:30PM

Textbooks/Other Materials

The partner U-M / Barnes & Noble Education textbook website is the official way for U-M students to view their upcoming textbook or course material needs, whether they choose to buy from Barnes & Noble Education or not. Students also can view a customized list of their specific textbook needs by clicking a "View/Buy Textbooks" link in their course schedule in Wolverine Access.

Click the button below to view and buy textbooks for BIOPHYS 421.002

View/Buy Textbooks


Syllabi are available to current LSA students. IMPORTANT: These syllabi are provided to give students a general idea about the courses, as offered by LSA departments and programs in prior academic terms. The syllabi do not necessarily reflect the assignments, sequence of course materials, and/or course expectations that the faculty and departments/programs have for these same courses in the current and/or future terms.

Click the button below to view historical syllabi for BIOPHYS 421 (UM login required)

View Historical Syllabi

CourseProfile (Atlas)

The Atlas system, developed by the Center for Academic Innovation, provides additional information about: course enrollments; academic terms and instructors; student academic profiles (school/college, majors), and previous, concurrent, and subsequent course enrollments.

CourseProfile (Atlas)