MCDB 448 - Telomerase Function in Stem Cells and Cancers
Fall 2022, Section 001
Instruction Mode: Section 001 is  In Person (see other Sections below)
Subject: Molecular, Cellular, and Developmental Biology (MCDB)
Department: LSA Molecular, Cellular, and Developmental Biology
See additional student enrollment and course instructor information to guide you in your decision making.


Requirements & Distribution:
With permission of instructor.
Enforced Prerequisites:
BIOLOGY 305 and (MCDB 310 or CHEM 351 or BIOLCHEM 415).
This course counts toward the 60 credits of math/science required for a Bachelor of Science degree.
May not be repeated for credit.
Rackham Information:
Rackham credit requires additional work.
Primary Instructor:
Start/End Date:
Full Term 8/29/22 - 12/9/22 (see other Sections below)
NOTE: Drop/Add deadlines are dependent on the class meeting dates and will differ for full term versus partial term offerings.
For information on drop/add deadlines, see the Office of the Registrar and search Registration Deadlines.


This course focuses on the chromosome end protection problem and the chromosome end replication problem that eukaryotic cells are faced with. Telomeres and telomerase are responsible for solving these problems and for protecting us from diseases such as cancer and stem cell dysfunction disorders. This course will discuss the functions of telomeres and telomerase, and the consequences of their dysfunction in cells. Instruction and discussion will occur via lectures delivered by the instructor and critical analysis of papers from the scientific literature.

Course Requirements:

Student performance will be evaluated based on performance in the in-class quizzes (each quiz being 10-15 min long and worth 10 points; up to 16 quizzes in total) based on the paper discussed in class and the lecture notes that preceded the paper-reading class. Each quiz is composed of short-answer based questions (5-10 of them in total). Typical papers discussed in class are from top scientific journals such as Nature, Cell, and Science. Although the discussion of the papers will be done in groups, quizzes are taken individually by students. There will be a mandatory Final exam at the end of the term. This exam is worth 20 points.

Intended Audience:

Advanced undergraduates in biology or related majors and graduate students

Class Format:

Instruction and discussion will occur via lectures delivered by the instructor and critical analysis of papers from the scientific literature. Two lectures/paper-reading sessions per week, each 1.5 hours long.


MCDB 448 - Telomerase Function in Stem Cells and Cancers
Schedule Listing
001 (LEC)
 In Person
WF 4:00PM - 5:30PM
8/29/22 - 12/9/22

Textbooks/Other Materials

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