Anne McNeil

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Anne McNeil

Arthur F. Thurnau Professor
Associate Professor Chemistry, College of Literature, Science, and the Arts
Associate Professor of Macromolecular Science and Engineering, College of Engineering

Office Location(s): 2817 Chemistry
Phone: 734.615.5204
ajmcneil@umich.edu
Research Group

  • About

    I. New Methods for the Chain-Growth Synthesis of p-Conjugated Polymers
    Organic p-conjugated polymers are promising materials for thin-film solar cells, light-emitting diodes, and transistors because they exhibit tunable optical and electrical properties and can be solution-processed onto large, flexible substrates. However, these materials have several limitations and synthetic methods that provide access to new polymers are needed. Although a Ni-catalyzed chain-growth method was recently reported, the narrow substrate scope, highly monomer-specific reaction conditions, and inefficient cross-propagation between two monomers has limited its utility. My group’s approach to overcome these challenges has involved (i) elucidating the chain-growth mechanism and competing reaction pathways and (ii) developing alternative ligands/catalysts for improved reactivity.

    II. Synthesis and Characterization of Gradient p-Conjugated Copolymers
    Organic p-conjugated polymers are an increasingly important class of materials because of their widespread application in electronic devices. Although there have been extensive studies aimed at controlling their physical, optical and electronic properties through synthetic modifications, processing conditions, and device designs, little is known about the effect of copolymer sequence because these materials have been synthetically inaccessible. The ability to tailor properties by simply altering the copolymer sequence should provide a powerful new design strategy for preparing the next-generation of tunable organic materials. We have been targeting gradient copolymers, which exhibit continuously changing composition along the polymer chain, because of their anticipated ability to stabilize polymer blends. These novel copolymers will exhibit unique physical, optical and electronic properties when self-assembled in solution and blended in films.

    III. Developing Stimuli-Responsive Materials based on Gelation
    Molecular gels are increasingly being investigated for diverse applications, including chemical sensing, bioresponsive materials, regenerative medicine, and environmental remediation. Despite these successes, recent efforts to either improve gel properties or extend their applications have been significantly limited because gelation remains a largely unpredictable phenomenon. It was recently estimated that over 1000 small-molecule based gelators have been reported in the literature, although most of these gelators were either discovered serendipitously or through extensive combinatorial screening methods. It has been difficult to elucidate design principles from this data set because seemingly subtle changes to these gelator structures have had unpredictable and often detrimental effects on their gelation ability. My group’s approach to overcome these challenges has involved (i) creating, testing, and modifying a new gelator design strategy and (ii) identifying the key structure-property relationships relevant to gelation.

    Awards

    Provost's Teaching Innovation Prize
    Arthur F. Thurnau Professor
    Class of 1923 Memorial Teaching Award, 2013
    Camille Dreyfus Teacher-Scholar Award, 2012
    LSA Excellence in Education Award, 2011
    NSF Career Award, 2010
    PECASE Award - Presidential Early Career Awards for Scientists and Engineers, 2010
    Beckman Young Investigator Award, 2009
    Chemistry Faculty Research Award, 2009
    Office of Naval Research Young Investigator Award, 2009
    Seyhan N. Ege Junior Faculty Award, 2009
    Thieme Chemistry Journal Award, Synthesis and Synlett, 2009
    Elizabeth Caroline Crosby Research Award, 2008
    William R. Roush Junior Faculty Career Development Award, 2008

    Representative Publications

    Palermo, E. F.; Darling, S. B.; McNeil, A. J. Conjugated Gradient Copolymers Suppress Phase Separation and Improve Stability in Bulk Heterojunction Solar Cells. J. Mater. Chem. C 2014, Advance Article.

    Bremmer, S. C.; McNeil, A. J.; Soellner, M. B. Enzyme-triggered Gelation: Targeting Proteases with Internal Cleavage Sites. Chem. Commun. 2014, 50, 1691–1693.

    Bryan, Z. J.; McNeil, A. J. Conjugated Polymer Synthesis via Catalyst-transfer Polycondensation (CTP): Mechanism, Scope and Applications. Macromolecules 2013, 46, 8395–8405.

    Palermo, E. F.; van der Laan, H. L.; McNeil, A. J. Impact of p-Conjugated Gradient Sequence Copolymers on Polymer Blend Morphology. Polym. Chem. 2013, 4, 4606–4611.

    Bryan, Z. J.; McNeil, A. J. Evidence for a Preferential Intramolecular Oxidative Addition in Ni-catalyzed Cross-coupling Reactions and their Impact on Chain-growth Polymerizations. Chem. Sci. 2013, 4, 1620-1624.

    Lee, S. R.; Bloom, J. W. G.; Wheeler, S. E.; McNeil, A. J. Accelerating Ni(II) Precatalyst Initiation using Reactive Ligands and its Impact on Chain-growth Polymerizations. Dalton Trans. 2013, 42, 4218-4222.

     

  • Education
    • Ph.D., Cornell University
      PostDoc, MIT
  • Research Areas of Interest
    • Energy Science
      Materials Chemistry
      Organic Chemistry
      Organometallic Chemistry
      Sensor Science
      Sustainable Chemistry
  • Fellowship
    • Sloan Research Fellowship, 2011
    • 3M Nontenured Faculty Grant, 2009
    • L'Oreal USA Fellowship for Women in Science, 2006