Research Themes

Aging and Neurodegenerative Diseases
Behavior and Neural Circuits
Biological Clocks and Sleep
Cell Cycle and Cancer Biology
Chromatin Biology, Epigenetics & Gene Regulation
Computational Biology
Genome Integrity
Hormones, Growth Factors and  Cytokines
Metabolism and Metabolic Diseases
Microbial Pathogenesis and Biofilms
Plant Molecular Biology
Protein Folding and Folding Diseases
Signal Transduction and Cell-Cell Communication
Stem Cells and Pluripotency
Stress Responses
Trafficking and Organelle Biogenesis

MCDB faculty work on many challenging basic research problems around these research themes. The laboratories that do work in that area are linked below each theme.

Aging & Neurodegenerative Diseases

Mohammed Akaaboune's Lab Ursula Jakob's Lab
Laura Buttitta's Lab John Kuwada's Lab
Cathy Collins's Lab Yanzhuang Wang's Lab
Cunming Duan's Lab Haoxing Xu's Lab

Behavior & Neural Circuits

Mohammed Akaaboune's Lab John Kuwada's Lab
Sara Aton's Lab Orie Shafer's Lab
Robert Denver's Lab Kwoon Wong's Lab
Rich Hume's Lab  

Biological Clocks & Sleep

Sara Aton's Lab Kwoon Wong's Lab
Orie Shafer's Lab  

Cell Cycle & Cancer Biology

Laura Buttitta's Lab Ann Miller's Lab
Ken Cadigan's Lab JK Nandakumar's Lab
Gyorgyi Csankovszki's Lab Lyle Simmons's Lab
Cunming Duan's Lab Yanzhuang Wang's Lab

 

Channels, Receptors, and Synapses

Mohammed Akaaboune's Lab Rich Hume's Lab
Sara Aton's Lab John Kuwada's Lab
Cathy Collins's Lab Orie Shafer's Lab
Cunming Duan's Lab Kwoon Wong's Lab
  Haoxing Xu's Lab

 

Chromatin Biology, Epigenetics, and Gene Regulation

Laura Buttitta's Lab Jianming Li's Lab
Ken Cadigan's Lab John Schiefelbein's Lab
Gyorgyi Csankovszki's Lab Andrzej Wierzbicki's Lab
Robert Denver's Lab Trisha Wittkopp's Lab
Cunming Duan's Lab  

 

Computational Biology

Gyorgyi Csankovszki's Lab John Schiefelbein's Lab
Anuj Kumar's Lab Andrzej Wierzbicki's Lab
Pamela Raymond's Lab Trisha Wittkopp's Lab

 

Genome Integrity

Laura Buttitta Lyle Simmons
Gyorgyi Csankovszki Andrzej Wierzbicki
JK Nandakumar Trisha Wittkopp

 

Hormones, Growth Factors, and Cytokines

Robert Denver Orie Shafer
Cunming Duan Yanzhuang Wang
Jianming Li Haoxing Xu
Pamela Raymond  

 

Metabolism & Metabolic Diseases

  • Mohammed Akaaboune
  • Amy Chang
  • Cunming Duan
  • Ursula Jakob
  • Yanzhuang Wang
  • Haoxing Xu

Microbial Pathogenesis & Biofilms

  • Jim Bardwell
  • Matt Chapman
  • Anuj Kumar
  • Ursula Jakob
  • Lyle Simmons
  • Haoxing Xu

 

Plant Molecular Biology

  • Steve Clark
  • Jianming Li
  • Erik Nielsen
  • Laura Olsen
  • Eran Pichersky
  • John Schiefelbein
  • Andrzej Wierzbicki

 

Protein Folding & Folding Diseases

  • Jim Bardwell
  • Amy Chang
  • Matt Chapman
  • Ursula Jakob
  • Jianming Li
  • Yanzhuang Wang

Signal Transduction & Cell-Cell Communication

  • Amy Chang
  • Matt Chapman
  • Steve Clark
  • Cathy Collins
  • Cunming Duan
  • Daniel Klionsky
  • Anuj Kumar
  • Jianming Li
  • Ann Miller
  • Pamela Raymond
  • John Schiefelbein
  • Yanzhuang Wang

Stem Cells & Pluripotency

Faculty involved are:

  • Laura Buttitta
  • Ken Cadigan
  • Steve Clark
  • Gyorgyi Csankovszki
  • JK Nandakumar
  • Pamela Raymond

 

Stress Responses

  • Jim Bardwell
  • Amy Chang
  • Cathy Collins
  • Bob Denver
  • Cunming Duan
  • Ursula Jakob
  • Dan Klionsky
  • Anuj Kumar
  • Jianming Li
  • Janine Maddock
  • Lyle Simmons
  • Yanzhuang Wang

Trafficking & Organelle Biogenesis

  • Mohammed Akaaboune
  • Amy Chang
  • Matt Chapman
  • Cathy Collins
  • Dan Klionsky
  • John Kuwada
  • Jianming Li
  • Janine Maddock
  • Erik Nielsen
  • Laura Olsen
  • Lyle Simmons
  • Yanzhuang Wang
  • Haoxing Xu