Theophile Raphael Professor of Neuroscience, Professor of Psychiatry and Psychology
M.D., Tel Aviv University
Area: Clinical

Contact Information

Email: liberzon@umich.edu
Psychology Office: 116C VAMC
Psychology Phone: 734-769-7392

Research and Teaching Interests

Emotional dysregulation (exaggerated or inappropriate emotional response) and inability to cognitively modulate this response, are the hallmarks of Psychiatric disorders like Posttraumatic stress disorder (PTSD), Phobia, and Depression. One of the main interests of our lab focuses on functional neuroanatomy of emotions of response to stress and trauma, and as it relates to pathophysiology of stress related disorders. We are investigating specific patterns of cognitive-emotional-somatic interaction and the underlying neurocircuitry in healthy controls and psychiatric patients, and the effects of abnormal interactions on emotional regulation and decision making processes.

 

Representative Publications

• Taylor SF and Liberzon I. Neural correlates of emotion regulation in psychopathology Trends in Cognitive Science. In Press
• Liberzon I, King AP, Britton JC, Phan KL, Abelson JA,Taylor SF: Paralimbic and Medial Prefrontal Cortical involvement in Neuroendocrine Responses to Traumatic Stimuli. Am. J. Psychiatry 2007 164: p. 1250-1258
• Liberzon I, Taylor SF, Phan KL, Britton JC, Fig LM, Bleuller JA, Koeppe RA, Zubieta JK: Altered Central m-Opioid Receptor Binding Following Psychological Trauma Biological Psychiatry 61(9):1030-1038, 2007
• Phan KL, Britton JC, Taylor SF, Fig LM, Liberzon I: Cortico-Limbic Blood Flow During Non-traumatic Emotional Processing in PTSD. Archives of General Psychiatry, 2006; 63: 184 * 192.
• Britton JC, Phan KL, Taylor SF, Welsh RC, Berridge KC, Liberzon I: Neural correlates of social and nonsocial emotions: An fMRI study. Neuroimage, 2006; 31(1):397-409
• Liberzon I and Martis B: Neuroimaging studies of emotional responses in PTSD. In Psychobiology of Posttraumatic Stress Disorder: A decade of progress. Annals York Academy of Science 2006 1071:87-109
• Abelson JL, Khan S, Liberzon I, Young EA: HPA axis activity in patients with panic disorder: Review and synthesis of four studies. Depression & Anxiety; 24:66-76. 2007
• Taylor SF, Martis B, Fitzgerald KD, Welsh RC, Abelson JL, Liberzon I, Himle JA, Gehring WJ: Medical frontal cortex activity and loss-related responses to errors. Journal of Neurosci, 2006; 26(15): 4063-70

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