Daniel Castro
Curriculum Vitae (PDF)PDF-logo


Biopsychology Graduate Student

email: castrod@umich.edu

General Research Interests:
I am intereste
d in how 'hedonic hotspots' in the brain generate pleasure and what neural circuits connect them. Areas of interest include the nucleus accumbens, the ventral pallidum, and lateral hypothalamus. Opioid and neuropeptide systems play a major role in my research.

Current Projects:

  • Comparing the effects of mu, delta, or kappa opioid receptor activation in the nucleus accumbens hotspot on pleasure 'liking'
  • Examining how projections from the lateral hypothalamus can modulate pleasure 'liking' via its inputs to the ventral pallidum hotspot
  • Examining whether or not parabrachial nucleus contains a hedonic hotspot

Techniques:
Optogenetics, microdialysis, cranial/oral cannula implants, microinjections, taste reactivity, food intake