Courses in Biological Chemistry (Division 517) Biol. Chem. 415. Introductory Biochemistry. Two terms of organic chemistry. No credit granted to those who have completed or are enrolled in Biol. 310 or 311, or Chem. 451/452. I. (3-4). (Excl). (BS). A one-term introductory biochemistry course that covers the biochemistry of the living state; the chemistry of amino acids, proteins, nucleic acids, carbohydrates, lipids, and steroids; energy transformations and chemical reactions in living cells; function of immune system and action of hormones; and self-regulation and self-replication of living organisms. Students may elect a fourth credit hour by participating in a weekly seminar, presented jointly by clinicians and basic scientists, which correlates 415 lecture material with human disease through the use of clinical case studies. Biol. Chem. 416. Introductory Biochemistry Laboratory. Quantitative Analysis; Prior or concurrent election of Biol. Chem. 415 or Chem. 451/452. No credit granted to those who have completed or are enrolled in Biol. 429 or Biol. Chem. 516. I. (3). (Excl). (BS). Laboratory fee ($50) required. A basic course in how to conduct and interpret biochemical laboratory experiments. Experiments include: spectrophotometry, enzymatic (including coupled) and protein assays, enzyme purification and kinetics, thermodynamic measurements, DNA manipulations, including mapping and cloning, PCR, and forensic testing. Biol. Chem. 499. Biochemical Research for Undergraduates: Laboratory. Biol. Chem. 415 or Chem. 451/452; permission of the course director. I, II, and III. (1-6; 1-4 in the half-term). (Excl). (INDEPENDENT). May be repeated for credit. This course provides an opportunity for students to develop a special research project under the direct supervision of a faculty member. Biol. Chem. 576/Pharmacology 568/Physiology 576. Signal Transduction. Two terms of organic chemistry; Biol. Chem. 415 or Chem. 451/452, and Biol. Chem. 570. Physical Chemistry is strongly recommended. I. (1). (Excl). (BS). Receptors; effector systems; oncogenes as signal transducers; interactions of signal transduction pathways. Biol. Chem. 578. Biochemical Techniques. Two terms of organic chemistry; Biol. Chem. 415 or Chem. 451/452. Physical chemistry is strongly recommended. I. (1). (Excl). (BS). In-depth discussions of important techniques in biochemistry research, including primary sequence determination of proteins; protein purification; spectroscopy; computer-assisted analysis of structure; computer analysis of DNA and protein sequences; protein chemistry; immunological techniques; identifying a gene in a library; electrophoresis; and, directed mutagenesis. University of Michigan | College of LS&A | Student Academic Affairs | LS&A Bulletin Index | Department Homepage Queried: 5:48 PM EST on Thu, May 4, 2000 This page maintained by LS&A Academic Information and Publications, 1228 Angell Hall Copyright © 2000 The Regents of the University of Michigan, Ann Arbor, MI 48109 USA +1 734 764-1817 Trademarks of the University of Michigan may not be electronically or otherwise altered or separated from this document or used for any non-University purpose.