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01-02 LS&A Bulletin

Courses in Chemistry (Division 334)


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CHEM 105 / AOSS 105. Our Changing Atmosphere.
(3). (NS). (BS).
The greenhouse effect, stratospheric ozone depletion, the polar ozone holes, and urban smog are discussed from a scientific perspective using the latest information. Human-induced change in atmospheric composition is a primary vehicle for Global Change. These changes can affect atmospheric motions, including jet streams, fronts and violent storms. The atmosphere interacts with all other components of the environment: the oceans, the geosphere (solid earth), the biosphere (living plants and animals), and the cryosphere (glaciers and ice-caps). These interactions and "feedback mechanisms" are a central theme of this course, which is intended for non-science concentrators.
CHEM 108 / GEOSCI 130 / PHYSICS 119. The Physical World.
High-school algebra. (4). (NS). (BS). (QR/2).
A lecture course which introduces physics, chemistry and algebraic concepts of Earth and Planetary Science on a quantitative basis.
CHEM 120. First Year Seminar in Chemistry.
Only first-year students, including those with sophomore standing, may pre-register for First-Year Seminars. All others need permission of instructor. (3). (NS).
These seminars, which are restricted to first-year students, are small group classes (approximately 15-25 students) taught by regular and emeritus faculty.
CHEM 125. General and Inorganic Chemistry: Laboratory.
To be elected by students who are eligible for (or enrolled in) Chem. 130. No credit granted to those who have completed Chem. 211. (2). (NS). (BS). Laboratory fee ($60) required.
One four-hour laboratory and one discussion. Basic laboratory techniques and applications to simple chemical systems.
CHEM 130. General Chemistry: Macroscopic Investigations and Reaction Principles.
Three years of high school math or Math. 105; one year of high school chemistry recommended. Placement by testing, or permission of Chemistry department. Intended for students without AP credit in chemistry. (3). (NS). (BS). (QR/2).
Introduction to the major concepts of chemistry, including the microscopic picture of atomic and molecular structure, periodic trends in chemical reactivity, the energetics of chemical reactions and the nature of chemical equilibria. Students are introduced both to the fundamental principles of modern chemistry and to the underlying theories that account for observed macroscopic behavior. Students learn to think critically, examine experimental data, and form generalizations about data as chemists do. Three lectures and one discussion. A special section of 130 is reserved for students who would benefit from a smaller lecture section and more frequent contact with both senior faculty and teaching assistants. Four lectures and one discussion. Approval of a counselor is required for registration in this section.
CHEM 210. Structure and Reactivity I.
High school chemistry. Placement by examination during Orientation. To be taken with Chem. 211. (4). (NS). (BS).
The content of organic chemistry is used to introduce students to major concepts of chemistry including ideas about bonding, energy, equilibrium, kinetics, stereochemistry, and the relationship between the structure and the reactivity of a chemical species. Three lectures and one discussion.
CHEM 211. Investigations in Chemistry.
To be taken with Chem. 210. (1). (NS). (BS). Laboratory fee ($67.50) required.
An introduction to laboratory techniques in chemistry using inorganic and organic compounds, with emphasis on thin layer chromatography, stoichiometry, acid-base chemistry, and microscale organic reactions. Four-hour laboratory.
CHEM 215. Structure and Reactivity II.
Chem. 210/211. To be taken with Chem. 216. (3). (NS). (BS).
Continuation of Chemistry 210. Students get further practice in applying the major concepts of chemistry to predicting the physical and chemical properties of organic compounds, including macromolecules, both synthetic and biological. Three lectures and informal help/tutoring sessions for students who need them.
CHEM 216. Synthesis and Characterization of Organic Compounds.
Chem. 210/211. Must be taken with Chem. 215. (2). (NS). (BS). Laboratory fee ($62.50) required.
Students participate in a number of projects in which they have to decide how to synthesize an organic compound on a microscale, then how to purify and how to characterize the compound using chromatographic and spectroscopic techniques. One lecture and a four-hour laboratory.
CHEM 218. Independent Study in Biochemistry.
Permission of instructor. For students with less than junior standing. (1). (Excl). (BS). (INDEPENDENT). May be repeated for a total of four credits.
Undergraduate biochemistry research.
CHEM 219. Independent Study in Chemistry.
Permission of instructor. For students with less than junior standing. (1). (Excl). (BS). (INDEPENDENT). May be repeated for a total of four credits.
Research in an area of interest to, and supervised by, a departmental faculty member.
CHEM 230. Physical Chemical Principles and Applications.
Chem. 215/216. Students who plan to continue beyond a fourth term in chemistry would typically enroll in Chemistry 260/241/242 instead of Chemistry 230; credit will not be given for both of these courses. No credit granted to those who have completed or are enrolled in Chem. 260. (3). (NS). (BS).
An introduction to the physical principles underlying some of the major topics of inorganic and analytical chemistry. The liquid and solid states of matter, phase transitions, solutions, electrochemistry, coordination complexes, spectroscopy, and the principles of thermodynamics that explain observed chemical reactions are studied from the viewpoint of the experimental scientist, with an emphasis on the application of chemical principles to a wide range of professions. Three lectures and one discussion.
CHEM 241. Introduction to Chemical Analysis.
Prior or concurrent enrollment in Chem. 260. (2). (NS). (BS).
Introduction to the chemical basis of both classical wet analysis methods and modern instrumental analysis methods. Course emphasizes statistical methods and the analytical applications of equilibria, electrochemistry, spectroscopy, and radioactivity.
CHEM 242. Introduction to Chemical Analysis Laboratory.
Prior or concurrent enrollment in Chem. 260. (2). (NS). (BS). Laboratory fee ($50) required.
Introductory laboratory in wet chemical and modern instrumental analysis. Experiments emphasize equilibria, separations, electrochemistry, and spectroscopy.
CHEM 260. Chemical Principles.
Chem. 215/216, Math. 115, and prior or concurrent enrollment in Phys. 140 (or 160). (3). (NS). (BS).
Introduction to the quantal nature of matter, basic chemical thermodynamics, and chemical kinetics. Description of the fundamental physical principles that underlie spectroscopic and electrochemical analysis
CHEM 261. Introduction to Quantum Chemistry.
Chem. 215/216, Math. 115, and prior or concurrent enrollment in Phys. 140 (or 160). Chem. 261 is intended primarily for Chemical Engineering students. No credit granted for students that have completed or are enrolled in Chem. 260. (1). (Excl). (BS).
Introduction to the quantal nature of matter and the basic principles of quantum chemistry. Course meets only for the first third of the term.
CHEM 302. Inorganic Chemistry: Principles of Structure, Reactivity, and Function.
Chem. 260 (or Chem. 261 and ChemE 330). (3). (NS). (BS).
This course provides an introduction to the structure and properties of those elements other than carbon. Topics include the electronic structure of atoms, molecules and extended solids, bonding, periodicity, main group and transition element chemistry, catalysis and bioinorganic chemistry. Three lectures and one discussion.
CHEM 312. Synthesis and Characterization.
Chem. 215/216. Prior or concurrent enrollment in Chem. 302. (2). (Excl). (BS). Laboratory fee ($70) required.
Introduces students to advanced techniques used in the synthesis, purification, and characterization of inorganic and organic compounds. Two four-hour laboratory periods.
CHEM 398. Undergraduate Research in Biochemistry.
Junior standing, and permission of a biochemistry concentration advisor and the professor who will supervise the research. (1-4). (Excl). (BS). (INDEPENDENT). May be repeated for a total of four credits during junior or senior year.
Undergraduate biochemistry research for students with junior standing or above.
CHEM 399. Undergraduate Research.
Junior standing, and permission of a chemistry concentration advisor and the professor who will supervise the research. (1-4). (Excl). (BS). (INDEPENDENT). May be repeated for a total of four credits during junior or senior year.
Elected starting in the junior or senior year, this course is a requirement for B.S. Chemistry students, who must elect it for a total of four credits spread out over two or more terms. The student must work on a research project supervised by a faculty member of the Chemistry Department, either alone, or in collaboration with a colleague within the department, from another department, or from another school. This collaboration must be an ongoing one, and the student must receive direct supervision by all of the faculty who have agreed to sponsor the project. Final evaluation of the research effort and the report, as well as the grade for the course, rests with the faculty member from the Chemistry Department. The student is expected to put in at least three hours a week of actual work for each credit hour elected. At the end of each term, a written report evaluating the progress of the project is submitted; one copy to the faculty member, one copy for the chemistry academic advisor and one copy for the student. Interim reports need not be lengthy, but the final report for Chemistry 399 is expected to be more detailed and longer than the reports in 219.
CHEM 402. Intermediate Inorganic Chemistry.
Chem. 302, and 461/462. (3). (Excl). (BS).
A second course in inorganic chemistry at the undergraduate level.
CHEM 417 / PHYSICS 417. Dynamical Processes in Biophysics.
Math. 216, and Phys. 340 or Chem. 463. (3). (Excl). (BS).
The physical basis of diffusive processes in biology and biochemistry, and optical spectroscopic means for measuring its rates. Topics include: membrane electrical potentials, nerve impulses, synaptic transmission, the physics of chemoreception by cells, motion and reaction kinetics of membrane components, optical microscopy, visible and UV light absorption, fluorescence and phosphorescence, quasielastic light scattering, mathematics of random fluctuations, and chaotic processes in biology.
CHEM 420. Intermediate Organic Chemistry.
Chem. 215/216. (3). (Excl). (BS).
An exploration of selected topics in organic chemistry that builds on the basic concepts of structure and reactivity considered in the first courses in organic chemistry.
CHEM 436. Polymer Synthesis and Characterization.
Chem. 260. (3). (Excl). (BS). Laboratory fee ($50) required.
A lecture and laboratory course that introduces students to the special techniques used to study macromolecules.
CHEM 447. Physical Methods of Analysis.
Chem. 260 and 241/242. (3). (Excl). (BS).
Theory and applicability of the principal physical and physiochemical approaches used in instrumental chemical analysis, including electrical, optical, and separation methods.
CHEM 451 / BIOLCHEM 451. Introduction to Biochemistry I.
Chem. 260; Biol. 162; and Math. 115. No credit granted to those who have completed or are enrolled in Biol. 310 or 311, or Biol. Chem. 415. (4). (Excl). (BS).
Chem. 451 is the first of a two-term introduction to modern biochemistry The course focuses on the chemical basis underlying a host of cellular events involving macromolecules such as proteins, nucleic acids, lipids, and glycoconjugates, in addition to small molecules such as vitamins, amino acids, and carbohydrates.
CHEM 452 / BIOLCHEM 452. Introduction to Biochemistry II.
Chem. 451. (4). (Excl). (BS).
Chem. 452 is the second of a two-term introduction to modern biochemistry. The course focuses on the chemical basis underlying a host of cellular events involving macromolecules such as proteins, nucleic acids, lipids, and glycoconjugates, in addition to small molecules such as vitamins, amino acids and carbohydrates.
CHEM 461. Physical Chemistry I.
Chem. 260, Phys. 240 (or 260), and Math. 215. (3). (Excl). (BS).
This is the second of a three term sequence in physical chemistry. This course builds on material introduced in Chemistry 260. The Schrödinger Equation is solved in 1-, 2-, and 3\_dimensions for important chemical problems. Group theory and quantum chemistry are used to understand chemical bonding and advanced spectroscopy. Should be elected in the same term as Chem. 462.
CHEM 462. Computational Chemistry Laboratory.
Math. 215, and prior or concurrent enrollment in Chem. 461. (1). (Excl). (BS).
Introduction to the use of modern computational tools (Mathematica and Maple) for problem solving and graphical presentation in chemistry. Use of molecular modeling software (HyperChem and CAChe) for calculation of molecular structure. Should be elected in the same term as Chemistry 461.
CHEM 463. Physical Chemistry II.
Chem. 461/462. (3). (Excl). (BS).
This is the third of a three term sequence in physical chemistry and focuses on thermodynamics and kinetics. Both classical thermodynamics (entropy, phase and chemical equilibria) and statistical thermodynamics are discussed. Fundamental theories underlying chemical kinetics are discussed and solid state structures are introduced.
CHEM 467 / GEOSCI 465 / AOSS 467. Biogeochemical Cycles.
Math. 116, Chem. 210, and Phys. 240 (or 260). (3). (Excl). (BS).
The biogeochemical cycles of water, carbon, nitrogen, and sulfur; the atmosphere and oceans as reservoirs and reaction media; the fate of natural and human-made sources of carbon, nitrogen, and sulfur compounds; the interactions among major biogeochemical cycles and resultant global change: greenhouse gases, acid rain, and ozone depletion.
CHEM 480. Physical and Instrumental Chemistry.
Chem. 447 and 461/462; and concurrent enrollment in Chem. 463. (3). (Excl). (BS). Laboratory fee ($50) required.
A laboratory exploration of methods for the measurement of physical and spectroscopic properties of substances and the application of these methods in instrumental analysis.
CHEM 485. Projects Laboratory.
Chem. 480. (2). (Excl). (BS). Laboratory fee ($50) required.
A project-oriented laboratory in which students work on one or two projects in depth during the term.
CHEM 495. Professional Development in the Chemical Sciences.
Chem. 461. (2). (Excl). Meets the ECB Junior/Senior Writing requirement.
A "studio" format course for students in the chemical sciences wishing to enhance their writing, speaking, and analysis skills. The course includes critical analysis and proficiency of written and oral communication and an introduction to the multi-faceted features of professional life.
CHEM 498. Undergraduate Honors Thesis in Biochemistry.
Chem. 398 and permission of instructor. To be elected in the term in which an Honors student presents a thesis on undergraduate research. (1). (Excl). (BS). (INDEPENDENT).
A course for students who present an undergraduate thesis as a result of research.
CHEM 499. Undergraduate Thesis.
Chem. 399 and permission of instructor. To be elected in the term in which an Honors student presents a thesis on undergraduate research. (1). (Excl). (BS). (INDEPENDENT).
A course for students who present an undergraduate thesis as a result of research.
CHEM 507. Inorganic Chemistry.
Chem. 461. (3). (Excl). (BS).
Structural concepts relating to inorganic and organometallic compounds, inorganic stereochemistry, crystal chemistry, coordination theory, ligand field theory, catalysis and generalizations about the periodic table.
CHEM 511. Materials Chemistry.
(3). (Excl). (BS).
This course presents concepts in materials chemistry. The main topics covered include structure and characterization, macroscopic properties and synthesis and processing.
CHEM 520 / BIOPHYS 520. Biophysical Chemistry I.
Chem. 463, Biol. Chem. 415, or Chem 420; permission of course director. (3). (Excl). (BS).
This course is the first of a two term biophysical chemistry series Biophysics 510/511. The course offers an overview of protein, nucleic acid, lipid and carbohydrate structures.
CHEM 521 / BIOPHYS 521. Biophysical Chemistry II.
Chem. 461, Biol. Chem. 415, and Chem. 430 or equivalent; and permission of course director. (3). (Excl). (BS).
This course gives background applications of several physical techniques used in biophysical research. General principles of spectroscopy are explained. Macromolecular structure determination by X-ray diffraction and two-dimensional NMR are treated in detail. IR, Raman, CD, EXAFS, EPR, and ESEEM are introduced.
CHEM 525 / BIOLOGY 525. Chemical Biology I.
Chemistry 451, 452, 461, and 463. (3). (Excl). (BS).
Exploration of the application of chemical principles to biology. Together with Chemistry 526, this constitutes a comprehensive one year introduction to the field of chemical biology.
CHEM 526 / BIOLOGY 526. Chemical Biology II.
Chem. 525. Prior or concurrent enrollment in Chemistry 402 or equivalent. (3). (Excl). (BS).
Exploration of the application of chemical principles to biology. Together with Chemistry 525, this constitutes a comprehensive one year introduction to the field of chemical biology.
CHEM 535 / MACROMOL 535. Physical Chemistry of Macromolecules.
Chem. 463. (3). (Excl). (BS).
This course stresses the theory and application of useful methods for studying natural and synthetic polymers.
CHEM 536 / MACROMOL 536. Laboratory in Macromolecular Chemistry.
Chem. 535 or Phys. 418. (2). (Excl). (BS). Laboratory fee ($50) required.
Experimental methods for the study of macromolecular materials in solution and in the bulk state.
CHEM 538 / MACROMOL 538. Organic Chemistry of Macromolecules.
Chem. 215/216 and Chem. 230 or 260. (3). (Excl). (BS).
The preparation, reactions, and properties of high molecular weight polymeric materials of both natural and synthetic origin.
CHEM 540. Organic Principles.
Chem. 312 and 461. (3). (Excl). (BS).
Fundamental principles of chemical binding, reaction mechanisms, and stereochemistry of organic compounds.
CHEM 541. Advanced Organic Chemistry.
Chem. 540. (3). (Excl). (BS).
Synthetic organic chemistry. The scope and limitations of the more important synthetic reactions are discussed within the framework of multistep organic synthesis.
CHEM 542. Applications of Physical Methods to Organic Chemistry.
Chem. 260, 241/242, and 312. (3). (Excl). (BS).
Applications of infrared, ultraviolet and nuclear magnetic resonance spectroscopy, optical rotary dispersion, mass spectrometry and other physical methods to the study of the structure and reactions of organic compounds.
CHEM 570. Molecular Physical Chemistry.
Chem. 461 and 463. (3). (Excl). (BS).
Basic concepts in modern chemical physics including molecular symmetry, group theory, operators, and introduction to the electronic structure of atoms and molecules.
CHEM 575. Chemical Thermodynamics.
Chem. 461. (3). (Excl). (BS).
A discussion of chemical phase equilibria, the treatment of solutions, and chemical reactions by classical thermodynamics. The applications of electrochemical cells in studying chemical reactivities, utilization of molecular and atomic spectra in statistico-mechanical calculations as well as a brief treatment of non-equilibrium thermodynamics are usually included.
CHEM 580. Molecular Spectra and Structure.
Chem. 570. (3). (Excl). (BS).
Review of atomic spectra; rotational, vibration-rotation and electronic spectra of diatomic and simple polyatomic molecules; and deduction of molecular parameters from spectra.


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