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02-03 LS&A Bulletin

Undergraduate Courses in Chemistry
SUBJECT=CHEM
(Division 334)


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CHEM 105 / AOSS 105 / ENSCEN 105. Our Changing Atmosphere.
(3). (NS). (BS).
The greenhouse effect, stratospheric ozone depletion, the polar ozone holes, and urban smog are discussed from a scientific perspective using the latest information. Human-induced change in atmospheric composition is a primary vehicle for Global Change. These changes can affect atmospheric motions, including jet streams, fronts and violent storms. The atmosphere interacts with all other components of the environment: the oceans, the geosphere (solid earth), the biosphere (living plants and animals), and the cryosphere (glaciers and ice-caps). These interactions and "feedback mechanisms" are a central theme of this course, which is intended for non-science concentrators.
CHEM 108 / GEOSCI 130 / PHYSICS 119. The Physical World.
High-school algebra. (4). (NS). (BS). (QR/2).
A lecture course which introduces physics, chemistry and algebraic concepts of Earth and Planetary Science on a quantitative basis.
CHEM 109 / PHYSICS 109. Natural Science: Bridging the Gaps.
(3). (NS). (BS).
An interdisciplinary, team-taught introduction to the scientific method, involving subject matter from physics, chemistry, astronomy, geology, biology, and ethics. Demonstrations provide nearly hands-on experience with relevant phenomena.
CHEM 120. First Year Seminar in Chemistry.
Only first-year students, including those with sophomore standing, may pre-register for First-Year Seminars. All others need permission of instructor. (3). (NS).
These seminars, which are restricted to first-year students, are small group classes (approximately 15-25 students) taught by regular and emeritus faculty.
CHEM 125. General and Inorganic Chemistry: Laboratory.
To be elected by students who are eligible for (or enrolled in) CHEM 130. No credit granted to those who have completed CHEM 211. (2). (NS). (BS). Laboratory fee ($60) required.
One four-hour laboratory and one discussion. Basic laboratory techniques and applications to simple chemical systems.
CHEM 130. General Chemistry: Macroscopic Investigations and Reaction Principles.
Three years of high school math or MATH 105; one year of high school chemistry recommended. Placement by testing, or permission of Chemistry department. Intended for students without AP credit in chemistry. (3). (NS). (BS). (QR/2).
Introduction to the major concepts of chemistry, including the microscopic picture of atomic and molecular structure, periodic trends in chemical reactivity, the energetics of chemical reactions and the nature of chemical equilibria. Students are introduced both to the fundamental principles of modern chemistry and to the underlying theories that account for observed macroscopic behavior. Students learn to think critically, examine experimental data, and form generalizations about data as chemists do. Three lectures and one discussion. A special section of 130 is reserved for students who would benefit from a smaller lecture section and more frequent contact with both senior faculty and teaching assistants. Four lectures and one discussion. Approval of a counselor is required for registration in this section.
CHEM 210. Structure and Reactivity I.
High school chemistry. Placement by examination during Orientation. To be taken with CHEM 211. (4). (NS). (BS).
The content of organic chemistry is used to introduce students to major concepts of chemistry including ideas about bonding, energy, equilibrium, kinetics, stereochemistry, and the relationship between the structure and the reactivity of a chemical species. Three lectures and one discussion.
CHEM 211. Investigations in Chemistry.
To be taken with CHEM 210. (1). (NS). (BS). Laboratory fee ($67.50) required.
An introduction to laboratory techniques in chemistry using inorganic and organic compounds, with emphasis on thin layer chromatography, stoichiometry, acid-base chemistry, and microscale organic reactions. Four-hour laboratory.
CHEM 215. Structure and Reactivity II.
CHEM 210/211. To be taken with CHEM 216. (3). (NS). (BS).
Continuation of Chemistry 210. Students get further practice in applying the major concepts of chemistry to predicting the physical and chemical properties of organic compounds, including macromolecules, both synthetic and biological. Three lectures and informal help/tutoring sessions for students who need them.
CHEM 216. Synthesis and Characterization of Organic Compounds.
CHEM 210/211. Must be taken with CHEM 215. (2). (NS). (BS). Laboratory fee ($62.50) required.
Students participate in a number of projects in which they have to decide how to synthesize an organic compound on a microscale, then how to purify and how to characterize the compound using chromatographic and spectroscopic techniques. One lecture and a four-hour laboratory.
CHEM 218. Independent Study in Biochemistry.
Permission of instructor. For students with less than junior standing. (1). (Excl). (BS). (INDEPENDENT). May be repeated for a total of four credits.
Undergraduate biochemistry research.
CHEM 219. Independent Study in Chemistry.
Permission of instructor. For students with less than junior standing. (1). (Excl). (BS). (INDEPENDENT). May be repeated for a total of four credits.
Research in an area of interest to, and supervised by, a departmental faculty member.
CHEM 230. Physical Chemical Principles and Applications.
CHEM 215/216. Students who plan to continue beyond a fourth term in chemistry would typically enroll in CHEM 260/241/242 instead of CHEM 230; credit will not be given for both of these courses. No credit granted to those who have completed or are enrolled in CHEM 260. (3). (NS). (BS).
An introduction to the physical principles underlying some of the major topics of inorganic and analytical chemistry. The liquid and solid states of matter, phase transitions, solutions, electrochemistry, coordination complexes, spectroscopy, and the principles of thermodynamics that explain observed chemical reactions are studied from the viewpoint of the experimental scientist, with an emphasis on the application of chemical principles to a wide range of professions. Three lectures and one discussion.
CHEM 241. Introduction to Chemical Analysis.
Prior or concurrent enrollment in CHEM 230 or 260, and concurrent enrollment in CHEM 242. (2). (NS). (BS).
Introduction to the chemical basis of both classical wet analysis methods and modern instrumental analysis methods. Course emphasizes statistical methods and the analytical applications of equilibria, electrochemistry, spectroscopy, and radioactivity.
CHEM 242. Introduction to Chemical Analysis Laboratory.
Prior or concurrent enrollment in CHEM 230 or 260, and concurrent enrollment in CHEM 241. (2). (NS). (BS). Laboratory fee ($50) required.
Introductory laboratory in wet chemical and modern instrumental analysis. Experiments emphasize equilibria, separations, electrochemistry, and spectroscopy.
CHEM 260. Chemical Principles.
CHEM 215/216, MATH 115, and prior or concurrent enrollment in PHYSICS 140 (or 160). (3). (NS). (BS).
Introduction to the quantal nature of matter, basic chemical thermodynamics, and chemical kinetics. Description of the fundamental physical principles that underlie spectroscopic and electrochemical analysis
CHEM 261. Introduction to Quantum Chemistry.
CHEM 215/216, MATH 115, and prior or concurrent enrollment in PHYSICS 140 (or 160). CHEM 261 is intended primarily for Chemical Engineering students. No credit granted for students that have completed or are enrolled in CHEM 260. (1). (Excl). (BS).
Introduction to the quantal nature of matter and the basic principles of quantum chemistry. Course meets only for the first third of the term.
CHEM 302. Inorganic Chemistry: Principles of Structure, Reactivity, and Function.
CHEM 260 (or CHEM 261 and CHE 330). (3). (NS). (BS).
This course provides an introduction to the structure and properties of those elements other than carbon. Topics include the electronic structure of atoms, molecules and extended solids, bonding, periodicity, main group and transition element chemistry, catalysis and bioinorganic chemistry. Three lectures and one discussion.
CHEM 312. Synthesis and Characterization.
CHEM 215/216. Prior or concurrent enrollment in CHEM 302. (2). (Excl). (BS). Laboratory fee ($70) required.
Introduces students to advanced techniques used in the synthesis, purification, and characterization of inorganic and organic compounds. Two four-hour laboratory periods.
CHEM 398. Undergraduate Research in Biochemistry.
Junior standing, and permission of a biochemistry concentration advisor and the professor who will supervise the research. (1-4). (Excl). (BS). (INDEPENDENT). May be repeated for a total of four credits during junior or senior year.
Undergraduate biochemistry research for students with junior standing or above.
CHEM 399. Undergraduate Research.
Junior standing, and permission of a chemistry concentration advisor and the professor who will supervise the research. (1-4). (Excl). (BS). (INDEPENDENT). May be repeated for a total of four credits during junior or senior year.
Elected starting in the junior or senior year, this course is a requirement for B.S. Chemistry students, who must elect it for a total of four credits spread out over two or more terms. The student must work on a research project supervised by a faculty member of the Chemistry Department, either alone, or in collaboration with a colleague within the department, from another department, or from another school. This collaboration must be an ongoing one, and the student must receive direct supervision by all of the faculty who have agreed to sponsor the project. Final evaluation of the research effort and the report, as well as the grade for the course, rests with the faculty member from the Chemistry Department. The student is expected to put in at least three hours a week of actual work for each credit hour elected. At the end of each term, a written report evaluating the progress of the project is submitted; one copy to the faculty member, one copy for the chemistry academic advisor and one copy for the student. Interim reports need not be lengthy, but the final report for Chemistry 399 is expected to be more detailed and longer than the reports in 219.
CHEM 402. Intermediate Inorganic Chemistry.
CHEM 302, and 461/462. (3). (Excl). (BS).
A second course in inorganic chemistry at the undergraduate level.
CHEM 417 / PHYSICS 417. Dynamical Processes in Biophysics.
MATH 216, and PHYSICS 340 or CHEM 463. (3). (Excl). (BS).
The physical basis of diffusive processes in biology and biochemistry, and optical spectroscopic means for measuring its rates. Topics include: membrane electrical potentials, nerve impulses, synaptic transmission, the physics of chemoreception by cells, motion and reaction kinetics of membrane components, optical microscopy, visible and UV light absorption, fluorescence and phosphorescence, quasielastic light scattering, mathematics of random fluctuations, and chaotic processes in biology.
CHEM 420. Intermediate Organic Chemistry.
CHEM 215/216. (3). (Excl). (BS).
An exploration of selected topics in organic chemistry that builds on the basic concepts of structure and reactivity considered in the first courses in organic chemistry.
CHEM 436. Polymer Synthesis and Characterization.
CHEM 260. (3). (Excl). (BS). Laboratory fee ($50) required.
A lecture and laboratory course that introduces students to the special techniques used to study macromolecules.
CHEM 447. Physical Methods of Analysis.
CHEM 260 and 241/242. (3). (Excl). (BS).
Theory and applicability of the principal physical and physiochemical approaches used in instrumental chemical analysis, including electrical, optical, and separation methods.
CHEM 451 / BIOLCHEM 451. Introduction to Biochemistry I.
CHEM 260; BIOLOGY 162; and MATH 115. No credit granted to those who have completed or are enrolled in BIOLOGY 310 or 311, or BIOLCHEM 415. (4). (Excl). (BS).
CHEM 451 is the first of a two-term introduction to modern biochemistry The course focuses on the chemical basis underlying a host of cellular events involving macromolecules such as proteins, nucleic acids, lipids, and glycoconjugates, in addition to small molecules such as vitamins, amino acids, and carbohydrates.
CHEM 452 / BIOLCHEM 452. Introduction to Biochemistry II.
CHEM 451. (4). (Excl). (BS).
CHEM 452 is the second of a two-term introduction to modern biochemistry. The course focuses on the chemical basis underlying a host of cellular events involving macromolecules such as proteins, nucleic acids, lipids, and glycoconjugates, in addition to small molecules such as vitamins, amino acids and carbohydrates.
CHEM 453. Biophysical Chemistry I: Thermodynamics and Kinetics.
CHEM 260 (or CHEM 261 and ChemE 330), CHEM 451, PHYSICS 240, and MATH 215. (3). (Excl). No credit granted to those who have completed or are enrolled in CHEM 463.
First in a two-term biophysical chemistry sequence for biochemistry students. Emphasis on topics and applications relevant to biochemistry an modern biophysical chemistry, building on CHEM 260. Rigorous mathematical theory of classical thermodynamics is developed, including application to entropy, heat engines, solution properties, and phase and chemical equilibrium. Modern statistical thermodynamics, modern theories of fundamental reaction rates and enzyme kinetics and molecular transport theories will be described and developed.
CHEM 454. Biophysical Chemistry II: Macromolecular Structure and Dynamics.
CHEM 453 or 463, and CHEM 451/452 or equivalent. (3). (Excl).
This course builds on the CHEM 451-453 sequence and aims at providing an understanding of the structure and dynamics of biological macromolecules. After introducing the necessary nomenclature and reviewing thermodynamic principles, modern techniques to characterize the structure and dynamics of biopolymers is the focus. Sedimentation, electrophoresis, mass spectrometry, X-ray diffraction, scattering, and spectroscopic techniques such as absorption, circular dichroism, fluorescence, and NMR are covered. Both physical principles and practical applications in the Life Sciences are highlighted
CHEM 461. Physical Chemistry I.
CHEM 260, PHYSICS 240 (or 260), and MATH 215. (3). (Excl). (BS).
This is the second of a three term sequence in physical chemistry. This course builds on material introduced in CHEM 260. The Schrödinger Equation is solved in 1-, 2-, and 3-dimensions for important chemical problems. Group theory and quantum chemistry are used to understand chemical bonding and advanced spectroscopy. Should be elected in the same term as CHEM 462.
CHEM 462. Computational Chemistry Laboratory.
MATH 215, and prior or concurrent enrollment in CHEM 461. (1). (Excl). (BS).
Introduction to the use of modern computational tools (Mathematica and Maple) for problem solving and graphical presentation in chemistry. Use of molecular modeling software (HyperChem and CAChe) for calculation of molecular structure. Should be elected in the same term as Chemistry 461.
CHEM 463. Physical Chemistry II.
CHEM 461/462. (3). (Excl). (BS).
This is the third of a three term sequence in physical chemistry and focuses on thermodynamics and kinetics. Both classical thermodynamics (entropy, phase and chemical equilibria) and statistical thermodynamics are discussed. Fundamental theories underlying chemical kinetics are discussed and solid state structures are introduced.
CHEM 467 / GEOSCI 465 / AOSS 467. Biogeochemical Cycles.
MATH 116, CHEM 210, and PHYSICS 240 (or 260). (3). (Excl). (BS).
The biogeochemical cycles of water, carbon, nitrogen, and sulfur; the atmosphere and oceans as reservoirs and reaction media; the fate of natural and human-made sources of carbon, nitrogen, and sulfur compounds; the interactions among major biogeochemical cycles and resultant global change: greenhouse gases, acid rain, and ozone depletion.
CHEM 480. Physical and Instrumental Chemistry.
CHEM 447 and 461/462; and concurrent enrollment in CHEM 463. (3). (Excl). (BS). Laboratory fee ($50) required.
A laboratory exploration of methods for the measurement of physical and spectroscopic properties of substances and the application of these methods in instrumental analysis.
CHEM 485. Projects Laboratory.
CHEM 480. (2). (Excl). (BS). Laboratory fee ($50) required.
A project-oriented laboratory in which students work on one or two projects in depth during the term.
CHEM 495. Professional Development in the Chemical Sciences.
CHEM 461. (2). (Excl). Meets the Upper-Level Writing Requirement.
A "studio" format course for students in the chemical sciences wishing to enhance their writing, speaking, and analysis skills. The course includes critical analysis and proficiency of written and oral communication and an introduction to the multi-faceted features of professional life.
CHEM 498. Undergraduate Honors Thesis in Biochemistry.
CHEM 398 and permission of instructor. To be elected in the term in which an Honors student presents a thesis on undergraduate research. (1). (Excl). (BS). (INDEPENDENT).
A course for students who present an undergraduate thesis as a result of research.
CHEM 499. Undergraduate Thesis.
CHEM 399 and permission of instructor. To be elected in the term in which an Honors student presents a thesis on undergraduate research. (1). (Excl). (BS). (INDEPENDENT).
A course for students who present an undergraduate thesis as a result of research.
CHEM 507. Inorganic Chemistry.
CHEM 461. (3). (Excl). (BS).
Structural concepts relating to inorganic and organometallic compounds, inorganic stereochemistry, crystal chemistry, coordination theory, ligand field theory, catalysis and generalizations about the periodic table.
CHEM 511. Materials Chemistry.
(3). (Excl). (BS).
This course presents concepts in materials chemistry. The main topics covered include structure and characterization, macroscopic properties and synthesis and processing.
CHEM 520 / BIOPHYS 520. Biophysical Chemistry I.
CHEM 463, BIOLCHEM 415, or CHEM 420; permission of course director. (3). (Excl). (BS).
This course is the first of a two term biophysical chemistry series Biophysics 510/511. The course offers an overview of protein, nucleic acid, lipid and carbohydrate structures.
CHEM 521 / BIOPHYS 521. Biophysical Chemistry II.
CHEM 461, BIOLCHEM 415, and CHEM 430; and permission of course director. (3). (Excl). (BS).
This course gives background applications of several physical techniques used in biophysical research. General principles of spectroscopy are explained. Macromolecular structure determination by X-ray diffraction and two-dimensional NMR are treated in detail. IR, Raman, CD, EXAFS, EPR, and ESEEM are introduced.
CHEM 525 / MCDB 525. Chemical Biology I.
CHEM 451, 452, 461, and 463. (3). (Excl). (BS).
Exploration of the application of chemical principles to biology. Together with Chemistry 526, this constitutes a comprehensive one year introduction to the field of chemical biology.
CHEM 526 / MCDB 526. Chemical Biology II.
CHEM 525. Prior or concurrent enrollment in CHEM 402 or equivalent. (3). (Excl). (BS).
Exploration of the application of chemical principles to biology. Together with Chemistry 525, this constitutes a comprehensive one year introduction to the field of chemical biology.
CHEM 535 / MACROMOL 535. Physical Chemistry of Macromolecules.
CHEM 463. (3). (Excl). (BS).
This course stresses the theory and application of useful methods for studying natural and synthetic polymers.
CHEM 536 / MACROMOL 536. Laboratory in Macromolecular Chemistry.
CHEM 535 or PHYSICS 418. (2). (Excl). (BS). Laboratory fee ($50) required.
Experimental methods for the study of macromolecular materials in solution and in the bulk state.
CHEM 538 / MACROMOL 538. Organic Chemistry of Macromolecules.
CHEM 215/216, and 230 or 260. (3). (Excl). (BS).
The preparation, reactions, and properties of high molecular weight polymeric materials of both natural and synthetic origin.
CHEM 540. Organic Principles.
CHEM 312 and 461. (3). (Excl). (BS).
Fundamental principles of chemical binding, reaction mechanisms, and stereochemistry of organic compounds.
CHEM 541. Advanced Organic Chemistry.
CHEM 540. (3). (Excl). (BS).
Synthetic organic chemistry. The scope and limitations of the more important synthetic reactions are discussed within the framework of multistep organic synthesis.
CHEM 542. Applications of Physical Methods to Organic Chemistry.
CHEM 260, 241/242, and 312. (3). (Excl). (BS).
Applications of infrared, ultraviolet and nuclear magnetic resonance spectroscopy, optical rotary dispersion, mass spectrometry and other physical methods to the study of the structure and reactions of organic compounds.
CHEM 570. Molecular Physical Chemistry.
CHEM 461 and 463. (3). (Excl). (BS).
Basic concepts in modern chemical physics including molecular symmetry, group theory, operators, and introduction to the electronic structure of atoms and molecules.
CHEM 575. Chemical Thermodynamics.
CHEM 461. (3). (Excl). (BS).
A discussion of chemical phase equilibria, the treatment of solutions, and chemical reactions by classical thermodynamics. The applications of electrochemical cells in studying chemical reactivities, utilization of molecular and atomic spectra in statistico-mechanical calculations as well as a brief treatment of non-equilibrium thermodynamics are usually included.
CHEM 580. Molecular Spectra and Structure.
CHEM 570. (3). (Excl). (BS).
Review of atomic spectra; rotational, vibration-rotation and electronic spectra of diatomic and simple polyatomic molecules; and deduction of molecular parameters from spectra.

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