Courses in Chemistry (Division 334)

105/AOSS 105. Our Changing Atmosphere. (3). (NS). (BS).
The greenhouse effect, stratospheric ozone depletion, the polar ozone holes, and urban smog are discussed from a scientific perspective using the latest information. Human-induced change in atmospheric composition is a primary vehicle for Global Change. These changes can affect atmospheric motions, including jet streams, fronts and violent storms. The atmosphere interacts with all other components of the environment: the oceans, the geosphere (solid earth), the biosphere (living plants and animals), and the cryosphere (glaciers and ice-caps). These interactions and "feedback mechanisms" are a central theme of this course, which is intended for non-science concentrators.

106. Environmental Issues. (3). (NS). (BS).
Course examines current issues of human interactions with the environment. We show how the scientist's method of critical thinking and experimentation can be brought fruitfully to the explanation and possible solution to these issues.

108/Geol. 130/Phys. 119. The Physical World. High-school algebra. (4). (NS). (BS). (QR/2).
A lecture course which introduces physics, chemistry and algebraic concepts of Earth and Planetary Science on a quantitative basis.

125. General and Inorganic Chemistry: Laboratory. To be elected by students who are eligible for (or enrolled in) Chem. 130. No credit granted to those who have completed Chem. 211. (2). (NS). (BS). Laboratory fee ($60) required.
One four-hour laboratory and one discussion. Basic laboratory techniques and applications to simple chemical systems.

130. General Chemistry: Macroscopic Investigations and Reaction Principles. Three years of high school math or Math. 105; one year of high school chemistry recommended. Placement by testing, or permission of Chemistry department. Intended for students without AP credit in chemistry. (3). (NS). (BS). (QR/2).
Introduction to the major concepts of chemistry, including the microscopic picture of atomic and molecular structure, periodic trends in chemical reactivity, the energetics of chemical reactions and the nature of chemical equilibria. Students are introduced both to the fundamental principles of modern chemistry and to the underlying theories that account for observed macroscopic behavior. Students learn to think critically, examine experimental data, and form generalizations about data as chemists do. Three lectures and one discussion. A special section of 130 is reserved for students who would benefit from a smaller lecture section and more frequent contact with both senior faculty and teaching assistants. Four lectures and one discussion. Approval of a counselor is required for registration in this section.

210. Structure and Reactivity I. High school chemistry. Placement by examination during Orientation. To be taken with Chem. 211. (4). (NS). (BS).
The content of organic chemistry is used to introduce students to major concepts of chemistry including ideas about bonding, energy, equilibrium, kinetics, stereochemistry, and the relationship between the structure and the reactivity of a chemical species. Three lectures and one discussion.

211. Investigations in Chemistry. To be taken with Chem. 210. (1). (NS). (BS). Laboratory fee ($67.50) required.
An introduction to laboratory techniques in chemistry using inorganic and organic compounds, with emphasis on thin layer chromatography, stoichiometry, acid-base chemistry, and microscale organic reactions. Four-hour laboratory.

215. Structure and Reactivity II. Chem. 210/211. To be taken with Chem. 216. (3). (NS). (BS).
Continuation of Chemistry 210. Students get further practice in applying the major concepts of chemistry to predicting the physical and chemical properties of organic compounds, including macromolecules, both synthetic and biological. Three lectures and informal help/tutoring sessions for students who need them.

216. Synthesis and Characterization of Organic Compounds. Chem. 210/211. Must be taken with Chem. 215. (2). (NS). (BS). Laboratory fee ($62.50) required.
Students participate in a number of projects in which they have to decide how to synthesize an organic compound on a microscale, then how to purify and how to characterize the compound using chromatographic and spectroscopic techniques. One lecture and a four-hour laboratory.

218. Independent Study in Biochemistry. Permission of instructor. For students with less than junior standing. (1). (Excl). (INDEPENDENT). May be repeated for a total of four credits.
Undergraduate biochemistry research.

219. Independent Study in Chemistry. Permission of instructor. For students with less than junior standing. (1). (Excl). (INDEPENDENT). May be repeated for a total of four credits.
Research in an area of interest to, and supervised by, a departmental faculty member.

230. Physical Chemical Principles and Applications. Chem. 215/216. No credit granted to those who have completed or are enrolled in Chem. 260. No credit granted to those who have completed Chem 340. (3). (NS). (BS).
An introduction to the physical principles underlying some of the major topics of inorganic and analytical chemistry. The liquid and solid states of matter, phase transitions, solutions, electrochemistry, coordination complexes, spectroscopy, and the principles of thermodynamics that explain observed chemical reactions are studied from the viewpoint of the experimental scientist, with an emphasis on the application of chemical principles to a wide range of professions. Three lectures and one discussion.

241. Introduction to Chemical Analysis. Prior or concurrent enrollment in Chem. 260. No credit granted to those who have completed Chem. 340. (2). (NS). (BS).
Introduction to the chemical basis of both classical wet analysis methods and modern instrumental analysis methods. Course emphasizes statistical methods and the analytical applications of equilibria, electrochemistry, spectroscopy, and radioactivity.

242. Introduction to Chemical Analysis Laboratory. Prior or concurrent enrollment in Chem. 260. No credit granted to those who have completed Chem. 340. (2). (NS). (BS). Laboratory fee ($50) required.
Introductory laboratory in wet chemical and modern instrumental analysis. Experiments emphasize equilibria, separations, electrochemistry, and spectroscopy.

260. Chemical Principles. Chem. 215/216, Math. 115, and prior or concurrent enrollment in Phys. 140. No credit granted to those who have completed Chem. 340. (3). (NS). (BS).
Introduction to the quantal nature of matter, basic chemical thermodynamics, and chemical kinetics. Description of the fundamental physical principles that underlie spectroscopic and electrochemical analysis

261. Introduction to Quantum Chemistry. Chem. 215/216, Math. 115, and prior or concurrent enrollment in Phys. 140. Chem. 261 is intended primarily for Chemical Engineering students. No credit granted for students that have completed or are enrolled in Chem. 260. No credit granted to students who have completed Chem. 340. (1). (Excl). (BS).
Introduction to the quantal nature of matter and the basic principles of quantum chemistry. Course meets only for the first third of the term.

302. Inorganic Chemistry: Principles of Structure, Reactivity, and Function. Chem. 260 (or Chem. 261 and ChemE 330; or Chem. 340). (3). (NS). (BS).
This course provides an introduction to the structure and properties of those elements other than carbon. Topics include the electronic structure of atoms, molecules and extended solids, bonding, periodicity, main group and transition element chemistry, catalysis and bioinorganic chemistry. Three lectures and one discussion.

312. Synthesis and Characterization. Chem. 215/216. Prior or concurrent enrollment in Chem. 302. (2). (Excl). (BS). Laboratory fee ($70) required.
Introduces students to advanced techniques used in the synthesis, purification, and characterization of inorganic and organic compounds. Two four-hour laboratory periods.

398. Undergraduate Research in Biochemistry. Junior standing, and permission of a biochemistry concentration advisor and the professor who will supervise the research. (1-4). (Excl). (INDEPENDENT). May be repeated for a total of four credits during junior or senior year.
Undergraduate biochemistry research for students with junior standing or above.

399. Undergraduate Research. Junior standing, and permission of a chemistry concentration advisor and the professor who will supervise the research. (1-4). (Excl). (INDEPENDENT). May be repeated for a total of four credits during junior or senior year.
Elected starting in the junior or senior year, this course is a requirement for B.S. Chemistry students, who must elect it for a total of four credits spread out over two or more terms. The student must work on a research project supervised by a faculty member of the Chemistry Department, either alone, or in collaboration with a colleague within the department, from another department, or from another school. This collaboration must be an ongoing one, and the student must receive direct supervision by all of the faculty who have agreed to sponsor the project. Final evaluation of the research effort and the report, as well as the grade for the course, rests with the faculty member from the Chemistry Department. The student is expected to put in at least three hours a week of actual work for each credit hour elected. At the end of each term, a written report evaluating the progress of the project is submitted; one copy to the faculty member, one copy for the chemistry academic advisor and one copy for the student. Interim reports need not be lengthy, but the final report for Chemistry 399 is expected to be more detailed and longer than the reports in 219.

400. Philosophy, Principles and Practice for Chemical Science Teachers: Integrating the Precollegiate Lecture and Laboratory. Chem. 130. (2). (Excl). May not be included in a concentration plan in chemistry.
A lecture course where fundamental chemistry concepts are discussed, with an emphasis on translating these ideas into integrated lecture and laboratory work for the precollege classroom. These topics include chemical reactions, quantitative methods, recording observations, data collection and analysis, written and oral communication, philosophical, historical and social contexts for science instruction.

401. Philosophy, Principles and Practice for Chemical Science Teachers: Curriculum Enrichment for Precollegiate Chemistry. Chem. 130. (2). (Excl). May not be included in a concentration plan in chemistry. Laboratory fee ($50) required.
A lecture and laboratory course that includes the practical operations and techniques of chemistry. An emphasis is placed on translating these activities into integrated lecture and laboratory work for the precollege classroom. These topics include measurement, determining chemical and physical properties, separation, identification, and instrumentation methods.

402. Intermediate Inorganic Chemistry. Chem. 302, and 461/462 (or 469). (3). (Excl). (BS).
A second course in inorganic chemistry at the undergraduate level.

417/Physics 417. Dynamical Processes in Biophysics. Math. 216, and Phys. 340 or Chem. 463 (or 468). (3). (Excl). (BS).
The physical basis of diffusive processes in biology and biochemistry, and optical spectroscopic means for measuring its rates. Topics include: membrane electrical potentials, nerve impulses, synaptic transmission, the physics of chemoreception by cells, motion and reaction kinetics of membrane components, optical microscopy, visible and UV light absorption, fluorescence and phosphorescence, quasielastic light scattering, mathematics of random fluctuations, and chaotic processes in biology.

420. Intermediate Organic Chemistry. Chem. 215/216. (3). (Excl). (BS).
An exploration of selected topics in organic chemistry that builds on the basic concepts of structure and reactivity considered in the first courses in organic chemistry.

436. Polymer Synthesis and Characterization. Chem. 260 (or 340). (3). (Excl). (BS). Laboratory fee ($50) required.
A lecture and laboratory course that introduces students to the special techniques used to study macromolecules.

447. Physical Methods of Analysis. Chem. 260 and 241/242 (or 340). (3). (Excl). (BS).
Theory and applicability of the principal physical and physiochemical approaches used in instrumental chemical analysis, including electrical, optical, and separation methods.

451/Biol. Chem. 451. Introduction to Biochemistry I. Chem. 215, Biol. 152 or 195, and Math. 115. No credit granted to those who have completed or are enrolled in Biol. 311 or Biol. Chem. 415. (4). (Excl). (BS).
Chem. 451 is the first of a two-term introduction to modern biochemistry The course focuses on the chemical basis underlying a host of cellular events involving macromolecules such as proteins, nucleic acids, lipids, and glycoconjugates, in addition to small molecules such as vitamins, amino acids, and carbohydrates.

452/Biol. Chem. 452. Introduction to Biochemistry II. Chem. 451. (4). (Excl). (BS).
Chem. 452 is the second of a two-term introduction to modern biochemistry. The course focuses on the chemical basis underlying a host of cellular events involving macromolecules such as proteins, nucleic acids, lipids, and glycoconjugates, in addition to small molecules such as vitamins, amino acids and carbohydrates.

461. Physical Chemistry I. Chem. 260 (or 340), Phys. 240, and Math. 215. No credit granted to those who have completed Chem. 397 or 469. (3). (Excl). (BS).
This is the second of a three term sequence in physical chemistry. This course builds on material introduced in Chemistry 260. The Schrödinger Equation is solved in 1-, 2-, and 3-dimensions for important chemical problems. Group theory and quantum chemistry are used to understand chemical bonding and advanced spectroscopy. Should be elected in the same term as Chem. 462.

462. Computational Chemistry Laboratory. Math. 215, and prior or concurrent enrollment in Chem. 461. (1). (Excl). (BS).
Introduction to the use of modern computational tools (Mathematica and Maple) for problem solving and graphical presentation in chemistry. Use of molecular modeling software (HyperChem and CAChe) for calculation of molecular structure. Should be elected in the same term as Chemistry 461.

463. Physical Chemistry II. Chem. 461/462. No credit granted to those who have completed Chem. 396 or 468. (3). (Excl). (BS).
This is the third of a three term sequence in physical chemistry and focuses on thermodynamics and kinetics. Both classical thermodynamics (entropy, phase and chemical equilibria) and statistical thermodynamics are discussed. Fundamental theories underlying chemical kinetics are discussed and solid state structures are introduced.

467/AOSS 467/Geol. 465. Biogeochemical Cycles. Math. 116, Chem. 210, and Phys. 240. (3). (Excl). (BS).
The biogeochemical cycles of water, carbon, nitrogen, and sulfur; the atmosphere and oceans as reservoirs and reaction media; the fate of natural and human-made sources of carbon, nitrogen, and sulfur compounds; the interactions among major biogeochemical cycles and resultant global change: greenhouse gases, acid rain, and ozone depletion.

480. Physical and Instrumental Chemistry. Chem. 447 and 461/462; and concurrent enrollment in Chem. 463. (3). (Excl). (BS). Laboratory fee ($50) required.
A laboratory exploration of methods for the measurement of physical and spectroscopic properties of substances and the application of these methods in instrumental analysis.

485. Projects Laboratory. Chem. 480. (2). (Excl). (BS). Laboratory fee ($50) required.
A project-oriented laboratory in which students work on one or two projects in depth during the term.

495. Professional Development in the Chemical Sciences. Chem. 461. (2). (Excl). Meets the ECB Junior/Senior Writing requirement.
A "studio" format course for students in the chemical sciences wishing to enhance their writing, speaking, and analysis skills. The course includes critical analysis and proficiency of written and oral communication and an introduction to the multi-faceted features of professional life.

498. Undergraduate Honors Thesis in Biochemistry. Chem. 398 and permission of instructor. To be elected in the term in which an Honors student presents a thesis on undergraduate research. (1). (Excl). (INDEPENDENT).
A course for students who present an undergraduate thesis as a result of research.

499. Undergraduate Thesis. Chem. 399 and permission of instructor. To be elected in the term in which an Honors student presents a thesis on undergraduate research. (1). (Excl). (INDEPENDENT).
A course for students who present an undergraduate thesis as a result of research.

507. Inorganic Chemistry. Chem. 461 (or 469 or 397). (3). (Excl). (BS).
Structural concepts relating to inorganic and organometallic compounds, inorganic stereochemistry, crystal chemistry, coordination theory, ligand field theory, catalysis and generalizations about the periodic table.

511. Materials Chemistry. (3). (Excl). (BS).
This course presents concepts in materials chemistry. The main topics covered include structure and characterization, macroscopic properties and synthesis and processing.

520(Biophysics 610)/Biophysics 520. Biophysical Chemistry I. Chem. 463, Biol. Chem. 415, or Chem 420; permission of course director. (3). (Excl). (BS).
This course is the first of a two term biophysical chemistry series Biophysics 510/511. The course offers an overview of protein, nucleic acid, lipid and carbohydrate structures.

521(511)/Biophysics 521. Biophysical Chemistry II. Chem. 461, Biol. Chem. 415, and Chem. 430; and permission of course director. (3). (Excl). (BS).
This course gives background applications of several physical techniques used in biophysical research. General principles of spectroscopy are explained. Macromolecular structure determination by X-ray diffraction and and two-dimensional NMR are treated in detail. IR, Raman, CD, EXAFS, EPR, and ESEEM are introduced.

530. Introduction to Bioorganic Mechanisms. Chem. 215/216, and Chem. 260 (or 340). (3). (Excl). (BS).
Introduction to organic mechanistic chemistry of biological systems; carbohydrates, amino acids, proteins, enzymes, steroids, terpenes, alkaloids, etc., organic mechanisms.

535/Macromolecular Science 535. Physical Chemistry of Macromolecules. Chem. 463 (or 468). (3). (Excl). (BS).
This course stresses the theory and application of useful methods for studying natural and synthetic polymers.

536/Macromolecular Science 536. Laboratory in Macromolecular Chemistry. Chem. 535 or Phys. 418. (2). (Excl). (BS). Laboratory fee ($50) required.
Experimental methods for the study of macromolecular materials in solution and in the bulk state.

538/Macromolecular Science 538. Organic Chemistry of Macromolecules. Chem. 215/216 and Chem. 230 (or 340). (3). (Excl). (BS).
The preparation, reactions, and properties of high molecular weight polymeric materials of both natural and synthetic origin.

541. Advanced Organic Chemistry. Chem. 540. (3). (Excl). (BS).
Synthetic organic chemistry. The scope and limitations of the more important synthetic reactions are discussed within the framework of multistep organic synthesis.

542. Applications of Physical Methods to Organic Chemistry. Chem. 260, 241/242, and 312. (3). (Excl). (BS).
Applications of infrared, ultraviolet and nuclear magnetic resonance spectroscopy, optical rotary dispersion, mass spectrometry and other physical methods to the study of the structure and reactions of organic compounds.

567/AOSS 567. Chemical Kinetics. Chem. 461 (or 469) or AOSS 479. (3). (Excl). (BS).
Chemical Kinetics is the study of the rates and mechanisms of systems undergoing chemical change. The extraction of rate data from reacting systems and the utilization of such data in other reacting systems is central to chemistry in the laboratory and in the practical worlds of combustion science, atmospheric science, and chemical synthesis. This course introduces the treatment of complex chemical systems and fundamental ideas about chemical reaction rates in gases and in solutions. Computer software is utilized to treat complex reaction systems.

570. Molecular Physical Chemistry. Chem. 461 and 463 (or 468/469). (3). (Excl). (BS).
Basic concepts in modern chemical physics including molecular symmetry, group theory, operators, and introduction to the electronic structure of atoms and molecules.

575. Chemical Thermodynamics. Chem. 461 (or 469). (3). (Excl). (BS).
A discussion of chemical phase equilibria, the treatment of solutions, and chemical reactions by classical thermodynamics. The applications of electrochemical cells in studying chemical reactivities, utilization of molecular and atomic spectra in statistico-mechanical calculations as well as a brief treatment of non-equilibrium thermodynamics are usually included.

580. Molecular Spectra and Structure. Chem. 570. (3). (Excl). (BS).
Review of atomic spectra; rotational, vibration-rotation and electronic spectra of diatomic and simple polyatomic molecules; and deduction of molecular parameters from spectra.

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