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LSA Course Guide Search Results: UG, GR, Fall 2007, Dept = BIOLCHEM
Page 1 of 1, Results 1 — 7 of 7
BIOLCHEM 415 — Introductory Biochemistry
Section 001, LEC

Instructor: Uhler,Michael D; homepage

FA 2007
Credits: 3

Credit Exclusions: No credit granted to those who have completed or are enrolled in BIOLOGY 310 or 311, or CHEM 451/452.

A one-term introductory biochemistry course that covers the biochemistry of the living state, the chemistry of amino acids, proteins, nucleic acids, carbohydrates, lipids, and steroids, energy transformations and chemical reactions in living cells, function of immune system and action of hormones, and self-regulation and self-replication of living organisms. Students may elect to participate in BIOLCHEM 491, a weekly seminar presented jointly by clinicians and basic scientists, which correlates biochemistry lecture material with human disease through the use of clinical case studies.

Advisory Prerequisite: Two terms of organic chemistry

BIOLCHEM 416 — Introductory Biochemistry Laboratory
Section 001, LAB

Instructor: Zand,Robert; homepage
Instructor: Admiraal,Suzanne J
Instructor: Young,Matthew A

FA 2007
Credits: 3

Credit Exclusions: No credit granted to those who have completed or are enrolled in BIOLOGY 429 or BIOLCHEM 516.

A basic laboratory course in biochemical techniques. A basic course in how to conduct and interpret biochemical laboratory experiments. Experiments include: spectrophotometry, enzymatic (including coupled) and protein assays, enzyme purification and kinetics, thermodynamic measurements, DNA manipulations, including mapping and cloning, PCR, and forensic testing.

Advisory Prerequisite: Qualitative analysis; prior or concurrent election of BIOLCHEM 415 or 451/452 or CHEM 451/452

BIOLCHEM 451 — Introduction to Biochemistry I
Section 100, LEC

Instructor: Yocum,Charles F; homepage
Instructor: Karbstein,Katrin

FA 2007
Credits: 4

Credit Exclusions: No credit granted to those who have completed or are enrolled in BIOLOGY 310 or 311, or BIOLCHEM 415.

This course is the first in a two-term sequence designed for biochemistry concentrators. Emphasis is on developing the capacity of the students to think about complex biological processes in terms of the underlying chemistry. An introductory section on proteins is followed by sections on enzymes and coenzymes. The discussion of biochemical energetics includes sections on glycolysis, the tricarboxylic acid cycle, electron transport, photosynthesis, and carbohydrate metabolism. The course has three lectures and one discussion per week. There are three hour exams and a final exam.

TEXT: Biochemistry, Voet, ISBN 047119350x, with Solutions Manual, ISBN 0471468584, Wiley.

Advisory Prerequisite: CHEM,CHEM 215, 260, BIOLOGY 152, 162, or 195, MATH 115.

BIOLCHEM 499 — Biochemical Research for Undergraduates: Laboratory
Section 001, IND

FA 2007
Credits: 1 — 6

This course provides an opportunity for students to develop a special research project under the direct supervision of a department faculty member.

Advisory Prerequisite: BIOLCHEM 415 or 451/452; permission of the course director.

BIOLCHEM 501 — Chemical Biology I
Section 001, SEM

Instructor: Saper,Mark A; homepage

FA 2007
Credits: 3
Reqs: BS

This course will provide a high-level overview on the structure, function and chemistry of biological macromolecules including proteins, nucleic acids and carbohydrates. Topics include protein and nucleic acid folding, energetics of macromolecular interactions (kinetics and thermodynamics), and mechanistic enzymology. Using specific examples from the current literature, each topic will stress how chemists have used molecular level tools and probes to help understand the specific systems under study. The over arching theme in this course will be that structure and function are intimately linked.

BIOLCHEM 550 — Macromolecular Structure and Function
Section 001, LEC

Instructor: Engelke,David R; homepage
Instructor: Xu,Zhaohui

FA 2007
Credits: 3

Biological Chemistry 550, Macromolecular Structure and Function, covers fundamental aspects of protein, membrane and nucleic acid structures, macromolecular recognition and interactions in signaling, protein maturation, gene expression and catalysis. This course is composed of lectures and faculty-led discussions of the primary scientific literature.

Reading: Papers assigned as lecture background or for discussion sections will be available as PDFs on the course website. Lecturers might also provide references to defined sections of books that will be on reserve at the Taubman Medical Library to serve as background material.

These texts are:

Introduction to Protein Structure (Garland Press, Second Edition), by Carl Branden and John Tooze.

Biochemistry (John Wiley & Sons, Inc., Third Edition), by Donald Voet and Judith G. Voet.

Nucleic Acids: Structures, Properties, and Functions (University Science Books) edited by Victor Bloomfield, Donald Crothers, and Ignacio Tinoco

Genes VII (Oxford University) by Benjamin Lewin

Grading: The grading for this course will be based on two exams of equal weight (~35% each) and Discussion participation (~30%).

Advisory Prerequisite: Two terms Organic Chemistry, introductory Biochemistry/permission of instructor

BIOLCHEM 591 — Special Topics in Signal Transduction
Section 001, LEC

Instructor: Rui,Liangyou; homepage

FA 2007
Credits: 2

A literature based discussion course that will cover both seminal discoveries in signal transduction as well as recent advances in the field. The course will meet once per week for two hours, throughout the semester. Two research papers will be discussed each week. Grading will be based on short weekly problem sets and a presentation by each student. Prior course work in biochemistry and cell biology is strongly encouraged.

Advisory Prerequisite: Course in Biochemistry and signal transduction or Instructor permission

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