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LSA Course Guide Search Results: UG, GR, Fall 2007, Dept = MCDB
 
Page 1 of 1, Results 1 — 28 of 28
Title
Section
Instructor
Term
Credits
Requirements
MCDB 300 — Undergraduate Research
Section 001, IND

FA 2007
Credits: 1 — 3
Reqs: BS
Other: INDEPENDENT

MCDB 300 is intended primarily for juniors, including Biology or CMB Honors students, who wish to pursue independent research at an intermediate level in an area of biological science. Students may ask an appropriate faculty member in the Department of Molecular Cellular and Developmental Biology to direct the research project and supervise related readings. Alternatively, students may identify a research advisor in another LS&A department, the UM Medical School, or another unit on the UM campus. Students conducting independent research in such outside units must identify a co-sponsor within the Department of MCDB. Independent research is defined as a laboratory project in which the student will have a say in the design, conduct, and interpretation of experiments. Library research projects and lab projects which are strictly a technical training experience do not qualify for credit as undergraduate research. A final paper is required and must be approved by the research advisor.

Advisory Prerequisite: Eight credits of BIOLOGY/MCDB courses; 3.0 GPA in science courses; and permission of instructor.

MCDB 302 — Teaching Experience for Undergraduates
Section 001, IND

FA 2007
Credits: 1 — 3
Other: Expr

Undergraduates participating in this course are responsible for (1) aiding regularly assigned Teaching Assistants; (2) providing tutorial help for undergraduates enrolled in the course; (3) meeting regularly with discussion and laboratory sessions; and (4) participating with Teaching Assistants in instructional activities.

Advisory Prerequisite: Permission of instructor.

MCDB 306 — Introductory Genetics Laboratory
Section 001, LEC

Instructor: Jeyabalan,Santhadevi; homepage

FA 2007
Credits: 3
Reqs: BS

This course provides students with laboratory experience in basic genetic principles. Students will analyze patterns of inheritance, gene interaction, linkage relationship, and genetic mapping of unknown mutants of Drosophila through a series of genetic crosses. By using molecular techniques such as polymerase chain reaction (PCR) and gel electrophoresis, mutations in Caenorhabditis elegans will be mapped to chromosomal locations. The experiments in microbial genetics include mapping by conjugation in E. coli; recombination analysis by transduction using bacteria and phage; and complementation tests on 'his' mutants of yeast. Experiments in human population genetics include calculating allelic frequencies of PTC tasting in the class. Students also will be doing DNA fingerprinting of a VNTR locus using their own squamous epithelial cells. A computer exercise on bioinformatics is included.

One one-hour lecture on Mondays 1-2 p.m. and one three-hour lab are scheduled each week; an additional three to four hours of lab time per week are expected at irregular times. Students are expected to write one formal lab report, three short lab reports, and to keep a complete and accurate record of all results and analyses in a bound lab notebook. There are two tests given during the term.

Students will need to purchase a lab manual, which is available at one of the copy centers: MCDB 306 Genetics Laboratory Manual. S. Jeyabalan. Printed by Grade A Notes.

Advisory Prerequisite: Prior or concurrent enrollment in BIOLOGY 305

MCDB 307 — Developmental Biology
Section 001, LEC

Instructor: Schiefelbein Jr,John W; homepage
Instructor: Raymond,Pamela A

FA 2007
Credits: 3
Reqs: BS

Developmental Biology provides an introduction to the principles involved in the development of a single cell into a complex organism, which consists of many specialized tissues and organs. We emphasize experimental evidence from molecular, genetic, and cell biological studies, which has led to our current understanding of development. We also consider the developmental origin, properties, and potential of embryonic and adult stem cells and their applications. Reflecting the unity of life, we take a comparative approach, and discuss experiments in various vertebrate and invertebrate animal model systems and plant model systems that have elucidated fundamental developmental processes.

Enforced Prerequisites: BIOLOGY 305

MCDB 400 — Advanced Research
Section 001, IND

FA 2007
Credits: 1 — 3
Reqs: BS
Other: INDEPENDENT

Intended for those engaged in original laboratory research at an advanced level. This course number is most frequently elected by senior Honors students who have completed MCDB 300 and who are completing their research and writing their thesis. A final paper is required. (Refer to the description of MCDB 300 for more information.) The work in this course may continue for two semesters. A 'Y' grade can be reported at the end of the first-term to indicate work in progress. At the end of the second term of MCDB 400, the final grade is posted for both term's elections. Students interested in MCDB 400 should obtain the brochure MCDB Department Policies on Undergraduate Research from the Undergraduate Biology Program Office (1111 Natural Science Bldg).

Enforced Prerequisites: MCDB 300

Advisory Prerequisite: 12 credits of biology, 3.0 average in science, and permission of faculty member in biology

MCDB 411 — Protein Structure and Function
Section 001, LEC

Instructor: Bardwell,James

FA 2007
Credits: 3
Reqs: BS

Aim: In the first third of the class, students will be introduced to genomics, proteomics, and state of the art bioinformatics as it applies to protein sequence analysis and data base searching on the web. These are extremely important aspects of the Life Sciences. Current literature will then be used to discuss various topics of protein structure and protein function, paying special attention to the state of the important techniques in this field. The course will end with the discussion of protein folding diseases, such as Alzheimer's disease and mad cow disease. At the end of this class, students will have an excellent overview of protein folding and function; should be able to critically evaluate literature in this field; and will have the ability to use the web to solve their research problems.

Content: The class will be lecture as well as hands-on computer manipulation of sequences, modeling, and discussion. The class will also provide guidance in reading and interpreting original scientific literature. The course assumes a very basic level of computer competence. Students need to know how to log onto the Internet from a campus computer.

Course material consists of web resources and recent literature. There is no textbook.

Grading will be based on take-home assignments and two quizzes (midterm and finals).

Enforced Prerequisites: One of: BIOLOGY 310, 311, BIOLCHEM 415, 451, CHEM 451; or Graduate standing

MCDB 412 — Teaching Biochemistry by the Keller Plan
Section 001, REC

Instructor: Balazovich,Kenneth J; homepage

FA 2007
Credits: 3
Other: Expr

Undergraduates who previously have taken an introductory biochemistry course act as TAs for Introductory Biochemistry (BIOLOGY 311). TAs meet with the instructor for a two-hour class each week for presentations and discussions of teaching biochemistry. TAs also prepare an oral report on a recent advance in biochemistry, which they present to their peers and the instructor. The major roles of the TAs are to examine the students on their mastery of unit material and to help the students with explanations supplementary to the textbook. At the completion of an instructor-generated written quiz, the student and TA grade the quiz together. TAs learn considerable biochemistry by repeated teachings of unit materials and, in addition, profit from their experience as teachers and evaluators.

Textbook: Lehninger, Principles of Biochemistry. New edition.

Enforced Prerequisites: BIOLOGY 310, 311, BIOLCHEM 415, or CHEM 451

MCDB 418 — Endocrinology
Section 001, LEC

Instructor: Denver,Robert J

FA 2007
Credits: 3
Reqs: BS

This course focuses on recent advances in the study of animal hormones. The course covers the cellular origin and chemical nature of hormones, the cellular and molecular mechanisms of hormone action, the evolution of hormones and their receptors, and the roles of hormones in the control of development, growth, physiology, and behavior. The course concentrates on endocrine systems of vertebrates, including humans.

Vertebrate Endocrinology, David O. Norris. 4th edition.

Enforced Prerequisites: BIOLOGY 305; and one of: BIOLOGY 310, 311, BIOLCHEM 415, 451, CHEM 451; or Graduate standing

MCDB 419 — Endocrinology Laboratory
Section 001, LAB

Instructor: Pavgi, Sushama ; homepage

FA 2007
Credits: 3
Reqs: BS

This laboratory course provides hands-on experience with methods used in endocrinological investigations. The students will learn techniques ranging from the organismal to the molecular level. The course emphasizes hypothesis testing, modern techniques, and data analysis. Prior or concurrent enrollment in MCDB 418 is required to take this course. The enrollment is limited to 12 students. Students should be aware that this course uses live animals. The laboratory will meet twice a week (a four-hour session and a two-hour session); however, students should anticipate an additional two or three hours laboratory time at various (and occasionally odd) times in the week. Course assignments include a term paper, quizzes, and other short assignments.

Textbook: Laboratory Manual for MCDB 419 for the current term. Ed. S. Pavgi.

Prior or concurrent enrollment in MCDB 418 is required to take this course.

Advisory Prerequisite: Prior or concurrent enrollment in BIOLOGY 225 or 310 or 311, or MCDB 418 or 426.

MCDB 422 — Cellular and Molecular Neurobiology
Section 001, LEC

Instructor: Akaaboune,Mohammed; homepage

FA 2007
Credits: 3
Reqs: BS

This course deals primarily with the properties of individual nerve cells, and small groups of nerve cells. This provides the basis for understanding information processing by the nervous system, learning and memory, development of neurons, and neurological and psychiatric disorders. Considerable emphasis will be placed on understanding the molecules that endow the nervous system with these properties. Textbook: Principles of Neural Science by Kandel, Schwartz & Jessell. McGraw-Hill.

Enforced Prerequisites: BIOLOGY 310, 311, BIOLCHEM 415, or CHEM 451; or Graduate standing.

MCDB 423 — Introduction to Research in Cellular and Molecular Neurobiology
Section 001, LAB

Instructor: Ameziane,Rafiqa; homepage

FA 2007
Credits: 3
Reqs: BS

This course provides an introduction to state-of-the-art research approaches in cellular and molecular neurobiology. The course is divided into three modules: electrophysiological methods, anatomical methods, and molecular biological methods.

Enforced Prerequisites: BIOLOGY 222 or MCDB 422

MCDB 423 — Introduction to Research in Cellular and Molecular Neurobiology
Section 002, LAB

Instructor: Ameziane,Rafiqa; homepage

FA 2007
Credits: 3
Reqs: BS

This course provides an introduction to state-of-the-art research approaches in cellular and molecular neurobiology. The course is divided into three modules: electrophysiological methods, anatomical methods, and molecular biological methods.

Enforced Prerequisites: BIOLOGY 222 or MCDB 422

MCDB 427 — Molecular Biology
Section 001, LEC

Instructor: Chapman,Matthew R
Instructor: Maddock,Janine R; homepage

FA 2007
Credits: 4
Reqs: BS

Lectures and discussions are concerned with the following topics: the physical methods used in molecular biology; structure and coding capacity of DNA chromosomes; DNA replication; transcription, protein synthesis; prokaryotic and eukaryotic regulation; molecular aspects of development; transposable elements and genetic engineering.

Textbook: Molecular Biology, Weaver, R.F., 3rd edition. (McGraw-Hill)

Enforced Prerequisites: BIOLOGY 305; and BIOLOGY 310, 311, BIOLCHEM 415 or CHEM 451; or Graduate standing.

MCDB 432 — Biochemistry and Physiology of Prokaryotes
Section 001, LEC

Instructor: Bender,Robert A
Instructor: Jakob,Ursula H; homepage

FA 2007
Credits: 3
Reqs: BS

Deals with metabolic pathways in bacterial cells. It asks how they fit together, how they control the flux of metabolites, how they lead to a defined structure, and how they maintain a cell in the face of severe environmental changes.

Enforced Prerequisites: One of: BIOLOGY 310, 311, BIOLCHEM 415 or CHEM 451/452

MCDB 435 — Intracellular Trafficking
Section 001, LEC

Instructor: Chang,Amy

FA 2007
Credits: 3
Reqs: BS

Topics covered include the molecular basis of secretion, quality control, vesicle transport, protein sorting, and organelle biogenesis. Students are presented a few lectures introducing them to current issues. Most time is spent analyzing the latest experimental papers anticipated to have a large impact in the field. The course focuses on critical discussions of the experiments, interpretations, and conclusions of primary research papers.

Enforced Prerequisites: BIOLOGY 305 and MCDB 428; or Graduate standing.

MCDB 610 — Principles Neuroscience I
Section 001, SEM

Instructor: Maren,Stephen A; homepage

FA 2007
Credits: 4

NEUROSCI 601 represents the first half of a year long, graduate-level survey of neuroscience. The goals for NEUROSCI 601 and 602 are: 1) To provide our students with a sense of the state of current knowledge in molecular, cellular, developmental, integrative and cognitive neuroscience. Considerable emphasis is put on pulling together information obtained from different types of investigations (anatomical, physiological, behavioral, biochemical, genetic) to gain a balanced view of neuroscience. 2) To provide our students with a sense of how knowledge was obtained, by reading and discussing "classic papers." 3) To provide our students with a sense of where the current frontier is, by reading and discussing very recent papers. Each week this class meets for 3-5 hours, with a mix of lectures and discussion. The major topics treated in NEUROSCI 601 and 602 are: I) Excitable Membranes, II) Molecular Neuropharmacology, and III) Developmental Neurobiology.

Students who wish to study only a single area of neuroscience may register for single modules of the course (Module 1, Excitable membranes = NEUROSCI 611; Module 2, Molecular Neuropharmacology = NEUROSCI 612 or Pharmcology 615; Module 3, Development of the Nervous System= NEUROSCI 613) for one credit each. Students who complete NEUROSCI 601 will receive 4 credits.

Advisory Prerequisite: Enrollment in a Ph.D. program. Graduate students in Master's degree programs may register only with the permission of the instructor.

MCDB 611 — Excitable Membranes
Section 001, SEM

Instructor: Maren,Stephen A; homepage

FA 2007
Credits: 1

Represents the first half OF a year-long, graduate-LEVEL survey OF NEURO. The goals FOR NEUROSCI 601 AND 602 are : 1) TO provide our students WITH a sense OF the state OF CURRENT knowledge IN molecular, cellular, developmental, integrative AND cognitive Neuroscience. Considerable emphasis IS put ON pulling together information obtained FROM different types OF investigations(anatomical, physiological, behavioral, biochemical, genetic) TO gain a balanced VIEW OF Neuroscience. 2) TO provide our students WITH a sense OF how knowledge was obtained, BY reading AND discussing "classic papers." 3) TO provide our students WITH a sense OF WHERE the CURRENT frontier IS, BY reading AND discussing very recent papers. Each week this class meets FOR 3 — 5 hours, WITH a mix OF lectures AND discussion. The major topics treated IN NEUROSCI 601 AND 602 are : I) Excitable Membranes, II) Molecular Neuropharmacology, AND III) Developmental Neurobiology. Students who wish TO study ONLY a single area OF Neuroscience may register FOR single modules OF the course(Module 1, Excitable membranes = NEUROSCI 611; Module 2, Molecular Neuropharmacology = NEUROSCI 612 OR Pharmcology 615; Module 3, Development OF the Nervous System = NEUROSCI 613) FOR one credit each. Students who complete NEUROSCI 601 will receive 4 credits.

Advisory Prerequisite: Enrollment in a Ph.D. program. Graduate students in Master's degree programs may register only with the permission of the instructor.

MCDB 613 — Central Nervous System Physiology and Development
Section 001, SEM

Instructor: Maren,Stephen A; homepage

FA 2007
Credits: 1

Represents the first half of a year long, graduate-level survey of neuroscience. The goals for NEUROSCI 601 and 602 are: 1) To provide our students with a sense of the state of current knowledge in molecular, cellular, developmental, integrative and cognitive neuroscience. Considerable emphasis is put on pulling together information obtained from different types of investigations (anatomical, physiological, behavioral, biochemical, genetic) to gain a balanced view of neuroscience. 2) To provide our students with a sense of how knowledge was obtained, by reading and discussing "classic papers." 3) To provide our students with a sense of where the current frontier is, by reading and discussing very recent papers. Each week this class meets for 3-5 hours, with a mix of lectures and discussion. The major topics treated in NEUROSCI 601 and 602 are: I) Excitable Membranes, II) Molecular Neuropharmacology, and III) Developmental Neurobiology. Students who wish to study only a single area of neuroscience may register for single modules of the course (Module 1, Excitable membranes = NEUROSCI 611; Module 2, Molecular Neuropharmacology = NEUROSCI 612 or Pharmcology 615; Module 3, Development of the Nervous System= NEUROSCI 613) for one credit each. Students who complete NEUROSCI 601 will receive 4 credits.

Advisory Prerequisite: Enrollment in a Ph.D. program. Graduate students in Master's degree programs may register only with the permission of the instructor.

MCDB 614 — Experimental Models in Molecular, Cellular and Developmental Biology
Section 001, LEC

Instructor: Hume,Richard I; homepage

FA 2007
Credits: 3

This course introduces beginning Ph.D. students to model organisms widely used in molecular, cellular and developmental biology research and to several powerful experimental approaches that can be used to study these organisms. The emphasis is on understanding the types of experiments for which each organism is particularly well suited.

Advisory Prerequisite: REQUIRED — ENROLLMENT IN A LIFE SCIENCE PH.D PROGRAM. RECOMMENDED — INTRODUCTORY COURSES IN GENETICS AND BIOCHEMISTRY.

MCDB 632 — Experimental Genetics Systems
Section 001, LEC

Instructor: Meisler,Miriam H; homepage

FA 2007
Credits: 1

Two faculty members per session describe their application of genetics principles to analysis of specific biological questions. This new course is designed to provide Genetics Training Program students with systematic exposure to the range of genetics approaches in use within the Program, and to increase interaction between students and faculty in the program.

Advisory Prerequisite: Graduate standing, and current or past Genetics Training Program student.

MCDB 683 — Organogenesis of a Complex Tissue
Section 001, LEC

Instructor: Gumucio,Deborah L; homepage

FA 2007
Credits: 2

Two course modules are offered, one covering an aspect of stem cell biology (embryonic or adult stem cells) and the other focused on a specific organ system (development, maintenance, organ disease, artificial organs). Course content is different each year. Current module topics are listed at: http://www.med.umich.edu/cdb.

Advisory Prerequisite: BIOLOGY,Graduate Cell biology recommended, but not required. Graduate standing.

MCDB 700 — Advanced Studies
Section 001, IND

FA 2007
Credits: 1 — 8

An introduction to the research methods in zoology requiring examination of original literature, experimental work on the subject of investigation, and writing of a report.

Advisory Prerequisite: BIOLOGY,Permission of instructor

MCDB 800 — Biology Seminars
Section 001, SEM

Instructor: Olsen,Laura J; homepage

FA 2007
Credits: 1

A graduate seminar course providing opportunity to discuss current work and new developments in Molecular, Cellular, and Developmental Biology.

Advisory Prerequisite: Graduate standing and permission of instructor.

MCDB 800 — Biology Seminars
Section 002, SEM

Instructor: Olsen,Laura J; homepage

FA 2007
Credits: 1

A graduate seminar course providing opportunity to discuss current work and new developments in Molecular, Cellular, and Developmental Biology.

Advisory Prerequisite: Graduate standing and permission of instructor.

MCDB 800 — Biology Seminars
Section 003, SEM

Instructor: Maddock,Janine R; homepage

FA 2007
Credits: 1

A graduate seminar course providing opportunity to discuss current work and new developments in Molecular, Cellular, and Developmental Biology.

Advisory Prerequisite: Graduate standing and permission of instructor.

MCDB 801 — Supervised Teaching
Section 001, IND

FA 2007
Credits: 1 — 2

Seminars, demonstrations, and orientation for college teaching in biology. Available for all pre-candidate teaching assistants.

Advisory Prerequisite: Graduate standing and permission of instructor. Appointment as Teaching Assistant in Biology.

MCDB 990 — Dissertation/Precandidate
Section 001, IND

FA 2007
Credits: 1 — 8

Election for dissertation work by doctoral student not yet admitted as a Candidate.

Advisory Prerequisite: Election for dissertation work by doctoral student not yet admitted as a Candidate. Graduate standing.

MCDB 995 — Dissertation/Candidate
Section 001, IND

FA 2007
Credits: 8

Graduate School authorization for admission as a doctoral Candidate. N.B. The defense of the dissertation (the final oral examination) must be held under a full term Candidacy enrollment period.

Enforced Prerequisites: Graduate School authorization for admission as a doctoral Candidate

 
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