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Fall Academic Term 2001 Course Guide

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Courses in Biology

This page was created at 2:11 PM on Sat, Mar 17, 2001.

Fall Academic Term, 2001 (September 5 December 21)

Open courses in Biology
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Wolverine Access Subject listing for BIOLOGY

Fall Term '01 Time Schedule for Biology.

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BIOLOGY 100. Biology for Nonscientists.

Section 001.

Instructor(s): Karen A Ocorr (kocorr@umich.edu) , Marcy P Osgood (mosgood@umich.edu)

Prerequisites & Distribution: Some exposure to biology and chemistry at the high school level is assumed. Not open to those with Advanced Placement or "Departmental" credit in biology, nor to those concentrating in the biological sciences. Credit is granted for a combined total of 12 credits elected in introductory biology. (4). (NS). (BS).

Credits: (4).

Course Homepage: http://biology.lsa.umich.edu/~www/bio100

Biology 100 is a one-term course designed to introduce students to current biological concepts. The course consists of three hours of lecture per week plus a coordinated discussion session which occupies two hours per week. Biology 100 provides an introduction to some general principles of biology and concentrates on the areas of cell biology and biotechnology, genetics and genetic diseases, evolution, and environmental biology.

A major objective of this course is to point out to students the nature of the scientific process and illustrate the uses and non-uses of science in contemporary life. Wherever possible, the ethical and social implications of contemporary scientific effort will be discussed. This course is designed for students with a minimal background in the biological sciences, but we do assume some exposure to biology and chemistry at the high school level. Discussion sections enroll 20 students and are taught by graduate student instructors. In the discussion section, students have the opportunity to review material presented in lecture and participate in discussions of issues raised in the lecture segment.

Textbook: BioInquiry

Check Times, Location, and Availability Cost: 2 Waitlist Code: 1

BIOLOGY 101. Biology and Human Affairs.

Section 001.

Instructor(s): John H Vandermeer (jvander@umich.edu), Mark L Wilson

Prerequisites & Distribution: Credit is granted for a combined total of 12 credits elected in introductory biology. (4). (NS). (BS).

Credits: (4).

Course Homepage: No Homepage Submitted.

This course is an introduction to those aspects of biology that have direct applicability to the lives of people in today's world. It covers current controversies within biology, especially as they relate to human life and human affairs. Topics discussed include race, health, and the environment. Background information is given for each topic, but the emphasis is placed on the controversies and the role of science in human affairs. In addition to the two lectures per week, there is a two-hour discussion period in which the topics are further explored and films are frequently shown.

Textbook: Vandermeer, J. Reconstructing Biology.

Check Times, Location, and Availability Cost: 2 Waitlist Code: 1

BIOLOGY 103. Ecology: Principles and Applications.

Section 001.

Prerequisites & Distribution: Credit is granted for a combined total of 12 credits elected in introductory biology. (4). (NS). (BS).

Credits: (4).

Course Homepage: No Homepage Submitted.

This course introduces students to basic principles of the science of ecology and their application to the biological aspects of modern environmental problems. It also emphasizes developing skills for "thinking like a scientist," including designing and interpreting experiments or observations. Topics include biodiversity patterns and consequences, population dynamics, ecosystem functions, and conservation biology. Grades will be based on frequent in-class quizzes on material taught in lecture and discussion sections, on an independent library and computer research project, and on discussion section participation and written assignments. There is also one required full-day field trip on a weekend (alternative dates will be offered). The intended audience includes two groups: non-science concentrators with an interest in the natural world and those interested more specifically in the social aspects of environmental studies but who need background in the scientific aspects. There will be three lecture hours per week and one two-hour discussion section.

Rather than periodic hourly exams, the instructor plans to use weekly or biweekly in-class quizzes that take 20 minutes or less. Because these will be relatively short and frequent, even if the class grows large, the quizzes can incorporate short essays, as well as some simple review. There will also be an individual project that will involve library and computer research and perhaps some simple computer simulations. If the class is relatively small (~50), these can be presented in a poster session. One full-day weekend field trip is required. Finally, the discussion sections will have a number of assignments, that will be at least partly at the discretion of the individual GSIs.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: 1

BIOLOGY 105. Biology of Human Nutrition.

Section 001.

Instructor(s): George F Estabrook (gfred@umich.edu)

Prerequisites & Distribution: Credit is granted for a combined total of 12 credits elected in introductory biology. (4). (NS). (BS).

Credits: (4).

Course Homepage: No Homepage Submitted.

Several times a day you make a decision about whether to eat, and if so, what to eat. When, how much, and what kind of food you eat has a tremendous impact on how you feel, what you look like, how well you function, and what health you will enjoy (or suffer) throughout your life.

BIO 105 is a natural science course for undergraduates who want to learn what are human nutritional needs, and where and how people have gotten food to meet them. It will give students a biologically sound foundation on which to make judgments about personal and public health, related to food consumption and production. BIO 105 does not require any other prerequisite than a strong desire to learn about this subject for practical and personal empowerment. BIO 105 will discuss human physiology as it relates to human nutrition; the content and availability of nutrition in food sources; the effect on human health of dietary choices and how food has been and is now grown, processed, and marketed, and the impact of these practices on human health. Plenary lectures and small GSI-lead discussions.

Check Times, Location, and Availability Cost: 2 Waitlist Code: 3, Sign list posted on door of 2039 Nat. Sci.

BIOLOGY 110 / AOSS 171 / UC 110 / Geol. 171 / NR&E 110. Introduction to Global Change I.

Section 001.

Instructor(s): B Van Der Pluijm (vdpluijm@umich.edu) , Perry Samson (samson@umich.edu)

Prerequisites & Distribution: Credit is granted for a combined total of 12 credits elected in introductory biology. (4). (NS). (BS).

Credits: (4).

Course Homepage: No Homepage Submitted.

See Geological Sciences 171.001.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: No Data Given.

BIOLOGY 120. First Year Seminar in Biology.

Section 001 Emerging And Re-Emerging Infectious Diseases.

Instructor(s): Alice G Reinarz (areinarz@umich.edu)

Prerequisites & Distribution: Only first-year students, including those with sophomore standing, may pre-register for First-Year Seminars. All others need permission of instructor. Credit is granted for a combined total of 12 credits elected in introductory biology. (3). (NS). (BS).

First-Year Seminar,

Credits: (3).

Course Homepage: No Homepage Submitted.

During the age of discovery of antibiotics, medical scientists often expressed confidence in winning the "War on Disease." Microbes have prevailed, however, and recent news is filled with accounts of recurring and previously unknown threats. This seminar will examine clinical victories and failures to contain infectious diseases. Models will include polio, influenza, HIV infections, multi-drug resistant tuberculosis, and Ebola. This course is limited to 20 first-year students. The class will be primarily discussion format and will include oral presentations by students. The grade will be based on class discussion, group presentation, and written assignments. Textbooks used: The Coming Plague by Laurie Garrett (1995) Penguin Books, New York, and The Hot Zone by Richard Preston (1994), Anchor Books (Doubleday), New York.

Check Times, Location, and Availability Cost: 1 Waitlist Code: No Data Given.

BIOLOGY 162. Introductory Biology.

Section Exams Will Be Given Oct. 1, Oct. 22, Nov. 19, And Dec. 10, 6-8 P.M.

Instructor(s): John W Schiefelbein Jr (schiefel@umich.edu)

Prerequisites & Distribution: Prior or concurrent enrollment in Chemistry 130. Biology 162 is not open to students who have completed Biol. 152, 154 or 195. Credit is granted for a combined total of 12 credits elected in introductory biology. (5). (NS). (BS). Laboratory fee ($68) required.

Credits: (5).

Lab Fee: Laboratory fee ($68) required.

Course Homepage: No Homepage Submitted.

A one-term introductory course intended for concentrators in biology, other science programs, or preprofessional studies. Other suitably prepared students wishing detailed coverage of biology are also welcome. The aims of Biology 162 are:

  1. to provide factual and conceptual knowledge;
  2. to give an integrated overview of the central tenets of modern biology;
  3. to afford experience in obtaining and interpreting biological hypotheses; and
  4. to develop thinking and writing skills.

Topics in Biology 162 are divided among four areas:

  1. cellular and molecular biology;
  2. genetics;
  3. evolution; and
  4. ecology.

Students MUST:

  1. attend 3 lectures, 1 one-and-a-half hour discussion, and 1 three hour lab section each week;
  2. ATTEND THEIR ASSIGNED DISCUSSION AND LAB MEETINGS EACH WEEK STARTING WITH THEIR LAB AND DISCUSSIONS IN THE FIRST FULL WEEK OR THEIR SPACE MAY BE GIVEN TO SOMEONE ON THE WAITING LIST; and
  3. RESERVE the times and dates for the midterm and final exams (as specified in the Time Schedule) before enrolling.

Students usually purchase a textbook, lab manual, and course pack consisting of a syllabus and lecture notes. No other study guides or supplementary materials need be bought.

For Honors credit, register for one of the Honors discussion/lab sections.

For further information contact the Introductory Biology office, 1039 Chemistry Building (734) 764-1430.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: 2, Go to 1039 Chemistry.

BIOLOGY 200. Undergraduate Tutorial.

Prerequisites & Distribution: Permission of faculty member in biology. (2). (Excl). (BS). (INDEPENDENT). May be repeated for a total of six credits.

Credits: (2).

Course Homepage: No Homepage Submitted.

This course is intended for sophomores learning research and laboratory techniques, working under close supervision of a faculty member. It may also be used for directed readings at an appropriate level. It includes reading on a significant topic and regular consultation with the faculty member chosen to supervise the work. The required paper could be on the scientific literature in a broad field, on biological issues on which the student may want to do continuing work, or on the detailed results of research in a biological specialty. Conferences, seminars, readings, and assigned writings are used to develop critical perspectives on modern biological problems and to provide breadth and sense of historical continuity in biological thought.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: No Data Given.

BIOLOGY 201. Introduction to Research in the Life Sciences.

Section 001.

Instructor(s): Robert D Fogel (rfogel@umich.edu)

Prerequisites & Distribution: Grade of B+ or better in Biology 162. (1). (Excl).

Credits: (1).

Course Homepage: www.herb.lsa.umich.edu/teaching/bio201/bio201syllabus.htm

This course is designed to help students identify potential mentors for independent lab or field research. This course is particularly appropriate for students in Biology 162 or 305, 310, or 311 who hope to join the junior/senior Honors Program of the Biology Department. Membership in the LS&A freshman-sophomore Honors Program is not required.

This course will introduce students to the diversity of research opportunities and approaches to research in the biological sciences that are available on the Michigan campus, by having a variety of scientists who sponsor undergraduate research visit the class. Some of the scientists will be from the Department of Biology, while the rest will be from the Medical School and other schools at the University of Michigan. Students in the class will be evaluated based on two short papers, an oral presentation to the class, and on their participation in class discussion. Weekly reading assignments will form the basis of class discussion.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: 1

BIOLOGY 207. Introductory Microbiology.

Section 001.

Instructor(s): Paul V Dunlap

Prerequisites & Distribution: Biol. 162. (4). (NS). (BS). Satisfies a Biology laboratory requirement. Laboratory fee ($70) required.

Credits: (4).

Lab Fee: Laboratory fee ($70) required.

Course Homepage: No Homepage Submitted.

The course consists of three one-hour lectures and one three-hour laboratory session each week. The lectures describe the basic biology of microbial life, with emphasis on the domains Bacteria (eubacteria) and Archaea (archaebacteria), and including the domain Eucarya (protists and fungi). The fundamentals of microbial cell structure, metabolism and growth will be presented, together with the metabolic, ecological and phylogenetic diversity of microbes, their biotechnological applications and medical importance. The laboratory sessions will introduce microbiology laboratory practice, including microscopy, aseptic and pure-culture techniques, experimental manipulation and microbial enrichment, isolation, and characterization. Grades are based on three lecture exams and, in the laboratory sessions, on assessments of practical skills and weekly lab reports. The course is required for the microbiology concentration program, and it is appropriate for the biology concentration.

Textbook: Brock Biology of Microorganisms by Madigan, Martinko, Parker. Prentice Hall. Ninth Edition. 2000.

Check Times, Location, and Availability Cost: 3 Waitlist Code: 1

BIOLOGY 208. Embryology.

Section 001.

Instructor(s): Kathryn W Tosney (ktosney@umich.edu)

Prerequisites & Distribution: Biology 162. (3). (NS). (BS).

Credits: (3).

Course Homepage: http://biology.lsa.umich.edu/~www/bio208/index.html

In this Embryology course, we will study the entire organism as a function of time. We will seek to understand how a single cell, the fertilized egg, develops through time to form a multicellular organism. We will study the early stages of development, when cells divide and form the basic structures in the right places, establishing the basic body plan for each individual and initiating the development of different cell types.

We will study the embryo as it progresses through stages of cleavage, blastula formation, gastrulation, and organogenesis. We will maintain a focus on human development, but we will use animal models to understand developmental concepts such as differentiation, determination, epigenesis, and axis formation. Another goal is to develop conceptual and analytical skills, particularly the abilities to select and analyze information critically, to pose problems proficiently, to solve problems perceptively, to communicate persuasively, and to work as an effective part of a team. The course will combine lectures with facilitated peer-learning sessions and computer-intensive exercises.

Textbook: Developmental Biology by Scott F. Gilbert. 6th edition. Sinauer.

Check Times, Location, and Availability Cost: 2 Waitlist Code: 1

BIOLOGY 222. From Message to Mind: An Introduction to Neurobiology.

Section 001.

Instructor(s): Stephen S Easter Jr (sseaster@umich.edu)

Prerequisites & Distribution: Biol. 162. (3). (Excl). (BS).

Credits: (3).

Course Homepage: No Homepage Submitted.

An introduction to molecular, cellular, and systems-level neurobiology. Topics include: (1) bioelectricity; (2) intercellular communication; (3) sensory transduction and processing; (4) motor function; and (5) development of the brain and sensory systems. Students will be evaluated by exams, short papers, and problem sets. There are three lecture hours.

Check Times, Location, and Availability Cost: 2 Waitlist Code: 1

BIOLOGY 225(325). Principles of Animal Physiology: Lecture.

Section 001.

Instructor(s): Stephen S Easter Jr (sseaster@umich.edu) , Cunming Duan (cduan@umich.edu)

Prerequisites & Distribution: Biol. 162 and a year of chemistry. (3). (Excl). (BS).

Credits: (3).

Course Homepage: http://www.biology.lsa.umich.edu/courses/bio225/bio225.htm

This course is an introduction to the physiological view of animals. The course uses evidence from different groups of organisms to identify the general principles of functional mechanisms. It also considers variations in these mechanisms as related to the requirements of the animals but does not attempt a phylogenetic survey. The course is intended for concentrators and pre-medical students in their sophomore and junior years. The subject matter includes metabolism and temperature regulation, nervous and endocrine system controls and integration, respiration and circulation, water and ion balance, excretion, digestion, reproduction, and immune system function. There are three one-hour lectures a week, three one-hour examinations, and a final exam. The web site for this course is located at http://www.biology.lsa.umich.edu/courses/bio225/bio225.htm

TEXT: Biology, (5th ed.) by Campbell, Reece and Mitchell.

Check Times, Location, and Availability Cost: 2 Waitlist Code: 1

BIOLOGY 226(326). Animal Physiology Laboratory.

Section 001.

Instructor(s): Sushama Pavgi (spavgi@umich.edu)

Prerequisites & Distribution: Concurrent enrollment in Biol. 225 (or prior enrollment in 325, with permission). Students who intend at a later date to take Biol. 225 will not be admitted to Biol. 226 without special permission. (2). (Excl). (BS). Satisfies a Biology laboratory requirement. Laboratory fee ($70) required.

Credits: (2).

Lab Fee: Laboratory fee ($70) required.

Course Homepage: http://www.biology.lsa.umich.edu/~www/bio226/

This laboratory course provides hands-on experience with physiological systems at the level of organisms and organ systems. Prior or concurrent enrollment in BIO 225 is required to take this course. The laboratory meets for one four-hour session a week. Students perform experiments in small groups, collate class data, and perform analyses. Students should be aware that this course uses live animals. Each student is expected to lead one or more summary presentations at the beginning of the laboratory session following the conclusion of a previous laboratory exercise. The presentations will be 10-15 minutes in length and cover the analyses and summary of the data as well as provide conclusions and implications. Following the presentation, all students will be expected to contribute to the discussion. A term paper, an oral presentation and other short assignments are required during the term.

Laboratory Exercises in Animal Physiology, Biology 226, Winter 2001, edited by Dr. Sushama Pavgi is required for the course. It is available at Dollar Bill Copying, located at 611 Church Street (off South University Avenue).

Check Times, Location, and Availability Cost: 2 Waitlist Code: 1

BIOLOGY 230. Introduction to Plant Biology.

Section 001.

Instructor(s): Larry D Nooden (ldnum@umich.edu)

Prerequisites & Distribution: Biol. 162. (4). (NS). (BS). Laboratory fee ($65) required.

Credits: (4).

Lab Fee: Laboratory fee ($65) required.

Course Homepage: www.biology.lsa.umich.edu/~ldnum/bio230/230home.html

This course will provide a broad, integrated overview of plant biology including economic and environmental aspects. The general areas covered are:

  • Plant diversity the basic biology and evolution of the bacteria, fungi, algae, plantimals, bryophytes, and vascular plants. In addition, special aspects such as their environmental impacts, toxicology, cell biology, and molecular evolution will be covered.
  • Structure, function, and development from the cell-molecular level to the whole organism. Photosynthesis, internal transport, hormones, environmental controls, molecular biology, genetic engineering, and biotechnology will be included.
  • Ecology, adaptations to their environment, plant-animal interactions, ethnobotany, plant medicinals, biomes, biogeography, and evolution.

Students will also work with the Internet and electronic databases to answer questions in the course subject area. In addition to two hrs/week of lecture, there will be a discussion (one hr/week) and a lab (three hrs/week) with two field trips. Evaluations will be based on 2 one-hour exams, a final exam, four lab quizzes, and two short papers. Students will have to purchase a textbook, lab manual, and a course pack consisting of a syllabus and some illustrations. This course is not open to those who have completed Biology 154.

Check Times, Location, and Availability Cost: 3 Waitlist Code: 3

BIOLOGY 252. Chordate Anatomy and Phylogeny.

Section 001.

Instructor(s): William L Fink (wfink@umich.edu)

Prerequisites & Distribution: Biol. 162. (4). (Excl). (BS). Satisfies a Biology laboratory requirement. Laboratory fee ($60) required.

Credits: (4).

Lab Fee: Laboratory fee ($60) required.

Course Homepage: No Homepage Submitted.

This course teaches the comparative method, using the "three-fold parallelism" of anatomy, ontogeny, and paleontology. All examples are based on chordate animals, with emphasis on their anatomy and development. The introductory third of the course includes the theoretical basis of the comparative method, principles of evolutionary theory and speciation, and phylogenetics. The remainder of the course involves application of the method, with a survey of chordate structure, including the integument, skeleton, muscles, and the circulatory, urogenital, digestive, respiratory, and nervous systems. The laboratory provides practical experience in the comparative method, including dissections. There are three one-hour lectures per week and one three-hour laboratory. There are two hourly examinations and a final examination for the lecture, and a laboratory practical exam. A detailed syllabus and laboratory manual, rather than an assigned textbook, are used.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: No Data Given.

BIOLOGY 281. General Ecology.

Section 001.

Instructor(s): Beverly J Rathcke (brathcke@umich.edu) , Earl E Werner (eewerner@umich.edu)

Prerequisites & Distribution: Biol. 162 and a laboratory course in chemistry. No credit granted to those who have completed or are enrolled in Biol. 381. (3). (NS). (BS).

Credits: (3).

Course Homepage: www.biology.lsa.umich.edu/courses/bio281/bio281.html

The course introduces the basic concepts and principles of ecology as applied to the study of individuals, populations, and communities of both plants and animals. Course topics include the roles of physical and biotic factors influencing the distribution and abundance of organisms, the dynamics of population growth, species interactions including competition, predation, mutualism, the structure of ecological communities, ecological succession, and applications of ecology to problems of environment and resource management. Biology 281 is a suitable prerequisite for intermediate and advanced courses in ecology. There will be lectures, discussions, and computer simulations. Three exams will constitute the main basis of evaluation.

Textbook: Townsend, CR, J.L. Harper and M. Begon. Essentials of Ecology. Blackwell Science. (2000)

Check Times, Location, and Availability Cost: 1 Waitlist Code: No Data Given.

BIOLOGY 282. General Ecology Laboratory.

Section 011.

Instructor(s): Beverly J Rathcke (brathcke@umich.edu)

Prerequisites & Distribution: Biol. 162, a laboratory course in chemistry, and concurrent or prior enrollment in Biol. 281. (3). (Excl). (BS). Laboratory fee ($70) required.

Credits: (3).

Lab Fee: Laboratory fee ($70) required.

Course Homepage: www.biology.lsa.umich.edu/courses/bio281/bio281.html with a link to Bio 282

This laboratory course introduces the basic concepts and methods used in ecological research. The laboratories consist of both field and laboratory research projects, field trips, computer analyses, and an independent research project that is designed by each student. Students will write up laboratory reports and a paper on their independent research, give an oral presentation on their independent research, and participate in laboratory discussions.

Check Times, Location, and Availability Cost: 1 Waitlist Code: 1

BIOLOGY 288. Animal Diversity.

Section 001.

Instructor(s): Gerald Ray Smith (grsmith@umich.edu), Diarmaid O'Foighil

Prerequisites & Distribution: Biol. 162. (4). (NS). (BS). Laboratory fee ($70) required.

Credits: (4).

Lab Fee: Laboratory fee ($70) required.

Course Homepage: No Homepage Submitted.

Biology 288 will provide biology concentrators with a comprehension of the remarkable diversity of animal body plans present in nature. It will devote equal time to invertebrates and vertebrates and will consider the spectrum of multicellular animal life in the context of major issues in evolution and ecology. Diversity in morphology, development, life history, behavior and ecology will be addressed, with an emphasis on evolutionary innovations which underlay significant animal radiations. Laboratory exercises will demonstrate some of the above processes as well as anatomy, functional morphology, and hypotheses of adaptation. The laboratory exercises and lectures will be taxon based; processes will be touched upon repeatedly in a comparative manner.

This course is intended to serve the needs of Biology concentrators. There will be three one-hour lectures per week and three-hour lab session. Tests based on lecture material will be multiple choice and short answer questions. There will also be a term paper project and a lab practical exam.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: 1

BIOLOGY 300. Undergraduate Research.

Prerequisites & Distribution: Eight credits of biology and 3.0 grade point average in science; permission of faculty member in biology. (1-3). (Excl). (BS). (INDEPENDENT). May be repeated for a total of 9 credits.

Credits: (1-3).

Course Homepage: No Homepage Submitted.

Biology 300 intended primarily for juniors, including Honors students, who wish to pursue independent research or study at an intermediate level in an area of biological science. Students may ask an appropriate faculty member in the Department of Biology to direct the research project and supervise related readings. The project may take the form of an investigation of new problems in the field or laboratory, a detailed investigation of primary sources (a literature survey), development of new procedures or programs, design of a classroom experiment, etc. A final paper is required and must be approved by the research advisor.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: No Data Given.

BIOLOGY 302. Teaching Experience for Undergraduates.

Prerequisites & Distribution: Permission of instructor. (1-3). (Excl). May not be included in any of the Biological Sciences concentration programs. (EXPERIENTIAL).

Credits: (1-3).

Course Homepage: No Homepage Submitted.

Undergraduates participating in this course are responsible for:

  1. aiding regularly assigned Graduate Student Instructors;
  2. providing tutorial help for undergraduates enrolled in the course;
  3. meeting regularly with discussion and laboratory sessions; and
  4. participating with Graduate Student Instructors in instructional activities.
Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: No Data Given.

BIOLOGY 305. Genetics.

Section 001.

Instructor(s): Ronald E Ellis (ronellis@umich.edu)

Prerequisites & Distribution: Biol. 162, and prior or concurrent enrollment in Chem. 210. (4). (Excl). (BS).

Credits: (4).

Course Homepage: No Homepage Submitted.

Open to students concentrating in the natural sciences or intending to apply for graduate or professional study in basic or applied biology. This introduction to genetics includes the following sections: DNA and chromosomes; gene transmission in Eukaryotes; linkage and recombination; genes and enzymes, the genetic code, and mutation; recombinant DNA, RFLP mapping, the Human Genome Project; gene regulation, transposons; population genetics; and quantitative genetics.

There are three hours of lecture each week and one discussion section directed by GSIs. The discussion sections expand on and review lecture material, and discuss problem assignments. Grading is based on three term exams and a final covering lectures, discussions, and reading assignments. Exams include new problems that test applications of basic concepts and genetic techniques. A practice problem set is available and is covered in discussion sections or the Genetics Study Center. The three term exams are given Monday nights.

Texts:

  • Principles of Genetics (2nd edition) by Snustad and Simmons. This text is intended to supplement the lectures. We will refer to some figures from the text in lectures, but much of the lecture material will be novel.

  • Coursepack Problems 1-270, Available at Dollar Bill Copying.
Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: No Data Given.

BIOLOGY 306. Introductory Genetics Laboratory.

Section 001.

Instructor(s): Santhadevi Jeyabalan (sjeyabal@umich.edu)

Prerequisites & Distribution: Prior or concurrent enrollment in Biol. 305. (3). (Excl). (BS). Satisfies a Biology laboratory requirement. Laboratory fee ($70) required.

Credits: (3).

Lab Fee: Laboratory fee ($70) required.

Course Homepage: No Homepage Submitted.

This course provides students with laboratory experience on basic genetic principles. Students will analyze patterns of inheritance, gene interaction, linkage relationship, and genetic mapping of unknown mutants of Drosophila through a series of genetic crosses. By using molecular techniques such as Polymerase Chain Reaction (PCR) and gel electrophoresis, mutations in Caenorhabditis elegans will be mapped to chromosomal locations. The experiments in microbial genetics include mapping by conjugation in E. coli, recombination analysis by transduction using bacteria and phage, and complementation tests on "his" mutants of yeast. Experiments in Human Population Genetics include calculating allelic frequencies of PTC tasting in the class.

Students will also be doing DNA fingerprinting of a VNTR locus using their own squamous epithelial cells. One hour lecture on Mondays 1-2 PM and one three-hour lab are scheduled each week; additional 3-4 hours of lab time per week is expected at irregular times. Students are expected to write one formal lab report and to keep a complete and accurate record of all results and analyses in a bound lab notebook. There are two tests given during the term. Students will need to purchase a lab manual from Grade A Notes.

Check Times, Location, and Availability Cost: 1 Waitlist Code: 1

BIOLOGY 310. Introductory Biochemistry.

Section 001.

Instructor(s): Karen A Ocorr (kocorr@umich.edu)

Prerequisites & Distribution: Biol. 162; and organic chemistry. No credit granted to those who have completed or are enrolled in Biol. 311, Biol. Chem. 415, or Chemistry 451. (4). (Excl). (BS).

Credits: (4).

Course Homepage: http://biology.lsa.umich.edu/~www/bio310

Introductory Biochemistry is designed to be a general introduction to the chemistry of biological systems. The biweekly lectures for this course are designed to help student put biochemical reactions into a cellular context. Students are exposed to the strategies used by cells and multicellular organisms to coordinate the activity of various metabolic pathways. Topics covered include: protein structure and function; enzyme kinetics; molecular biology techniques, intermediary metabolism; photosynthesis; transcription; translation; and the hormonal regulation of metabolism.

In addition to the lectures, there is a weekly discussion session which has a project-based format. Students are provided with an opportunity to become more actively involved in their own learning experience and to further explore the relationship between biochemistry and the world around them through weekly mini-presentations. The weekly projects are designed to help students master the material using the Internet, scientific literature, etc. Discussion sessions are informal, allowing students ample opportunity to discuss the lecture topics and ask questions. There is an extensive web site for this course providing students with numerous additional resources to help them master the material (http://biology.lsa.umich.edu/~www/bio310/). Grades in this course are based on performance in the discussion session, two in-class exams, and a final exam.

Textbook: Lehringer's Principles of Biochemistry by Nelson and Cox. Absolute, Ultimate Guide to Principles of Biochemistry by Osgood and Ocorr.

Check Times, Location, and Availability Cost: 3 Waitlist Code: 1

BIOLOGY 311. Introductory Biochemistry.

Section 001 Self-Paced, Personalized System Of Instruction. Midterm Exam Wed., Oct. 17, 6:00 9:00 PM. Final Exam Fri., Dec. 14, 6:00 9:00 PM.

Instructor(s): Marcy P Osgood (mosgood@umich.edu)

Prerequisites & Distribution: Biol. 162; and organic chemistry. No credit granted to those who have completed or are enrolled in Biol. 310, Biol. Chem. 415, or Chem 451. (4). (Excl). (BS).

Credits: (4).

Course Homepage: http://biology.lsa.umich.edu/courses/bio311/

This course is taught by a self-paced, personalized system of instruction. Students interact, according to their own schedules, with undergraduate TA's. The student takes both a written and an oral quiz for each of 12 units which is graded and evaluated by the TA. If mastery is attained, the student may proceed to the next unit. Grades are assigned according to the number of units successfully completed and performance on the midterm and final examinations. This system is designed to take into consideration different rates of individual learning as well as to eliminate competition among students. TA's are available approximately 75-80 hours/week.

Textbook: Lehninger's Principles of Biochemistry. 3rd Edition.

Check Times, Location, and Availability Cost: 3 Waitlist Code: 1

BIOLOGY 324(224). Biology of Cancer.

Section 001.

Instructor(s): Lewis J Kleinsmith

Prerequisites & Distribution: Biol. 162. No credit granted to those who have completed or are enrolled in Biol. 124. (3). (NS). (BS).

Credits: (3).

Course Homepage: No Homepage Submitted.

The Biology of Cancer is a lecture/discussion course designed to provide students with a basic understanding of the biological events associated with the development of cancer. This course is organized around three fundamental questions: What is cancer; what are the causes of cancer; and can cancer be cured or prevented? Lectures will include descriptions of classical and recent experiments which address these questions, and will also provide students with the vocabulary and background needed to critically read and evaluate technical literature dealing with the subject of cancer. Periodic reading assignments from the textbook and course pack will be used to supplement lecture and discussion topics. Student performance will be evaluated by a combination of three exams and a term paper based upon library research. In order to provide the time required for this library research, the lecture-discussion meetings will be dismissed for approximately one week late in the term. The class will meet twice a week for an hour and a half lecture, and a weekly hour and a half discussion session will also be held. Textbook: How to Lie with Statistics by Darrell Huff.

Check Times, Location, and Availability Cost: 1 Waitlist Code: 1

BIOLOGY 355 / NR&E 337. Woody Plants I: Biology and Identification.

Section 001 Meets with NR&E 437.

Instructor(s): Burton V Barnes, Melanie Gunn

Prerequisites & Distribution: Biol. 162. (4). (Excl). (BS). Satisfies a Biology laboratory requirement. Laboratory fee ($45) required.

Credits: (4).

Lab Fee: Laboratory fee ($45) required.

Course Homepage: http://www.umich.edu/~nre437

The identification of trees, shrubs, and vines is the basis for the study of their biology and ecology. Woody plants are studied in their natural ecosystems including upland (oak-hickory, beech-sugar maple, lake plain), wetland (swamp, bog), and floodplain forests. Non-native species and ornamental plants are taught in the Saginaw Forest, Stinchfield Woods, Nichols Arboretum, and main campus. An introduction to the biology and ecology of woody plants is given in lectures.

Topics include vegetative and reproductive morphology; woody plant biology, ecology, and diversity; variation and genetics; systematics of woody plants; ornamental plants; and winter conditions. Also discussed are important trees of southern and western U.S., China, and the tropics. Field trips are scheduled from 1:00 to 6:00 once a week. Grading is based on 60% on plant identification (field quizzes and exams and indoor identification exams); 40% on lecture material (two hour-exams). Textbook: Michigan Trees (Barnes & Wagner, 1991, Univ. of Michigan Press).

Check Times, Location, and Availability Cost: 1 Waitlist Code: 3, Go to 1024 Dana Building

BIOLOGY 380. Oceanography: Marine Ecology.

Section 001.

Instructor(s): John T Lehman (jtlehman@umich.edu)

Prerequisites & Distribution: Biol. 162, and at least one term of college chemistry or physics. (3). (Excl). (BS).

Credits: (3).

Course Homepage: No Homepage Submitted.

Marine ecology is a study of the organisms and processes of the ocean, including both water and sediment communities. This course teaches physical and chemical aspects, but emphasizes biological aspects of oceanography, and applies ecological and evolutionary principles to the study of marine life. Lectures introduce the major groups of marine organisms and cover the interrelationships of marine organisms and their environments. Organisms and communities from the following habitats are discussed: estuaries; the rocky intertidal; coral reefs; the coastal zone; the deep sea; and the open ocean. The course treats organisms as different as bacteria and whales. This course is required for the Marine Biology option of the undergraduate Oceanography concentration. Grading is based on two one-hour exams plus a comprehensive final.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: No Data Given.

BIOLOGY 390. Evolution.

Section 001.

Instructor(s): Brian A Hazlett (bhazlett@umich.edu)

Prerequisites & Distribution: Biol. 162; prior or concurrent enrollment in Biol. 305. (4 in Ann Arbor; 5 at Biol. Station). (Excl). (BS).

Credits: (4 in Ann Arbor; 5 at Biol. Station).

Course Homepage: http://www.biology.lsa.umich.edu/courses/bio390/390index.html

This lecture course covers the fundamentals of evolutionary biology with a focus on living organisms. It includes a historical survey of the development of evolutionary theory from ancient philosophers to the present, and critical examination of phylogenetic systematics, natural selection, population genetics, molecular evolution, microevolution, and macroevolution. Weekly discussions will focus on primary literature. Two midterm tests and one cumulative final exam will test students' knowledge of lecture material. Writing assignment(s) based on readings from the primary scientific literature will be required. Textbook: Evolutionary Biology, 3rd Edition, D. J. Futnyma.

Check Times, Location, and Availability Cost: 2 Waitlist Code: 1

BIOLOGY 400. Advanced Research.

Prerequisites & Distribution: 12 credits of biology, 3.0 average in science, and permission of faculty member in biology. (1-3). (Excl). (BS). (INDEPENDENT). May be repeated for a total of 9 credits.

Credits: (1-3).

Course Homepage: No Homepage Submitted.

Intended for those engaged in original research at an advanced level. This course number is most frequently elected by senior Honors students who have completed Biology 300 and who are completing their research and writing their thesis. A final paper is required. (Refer to the description of Biology 300 for more information.)

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: No Data Given.

BIOLOGY 412. Teaching Biochemistry by the Keller Plan.

Section 001.

Instructor(s): Marcy P Osgood (mosgood@umich.edu)

Prerequisites & Distribution: Biol. 311 and permission of instructor. (3). (Excl). This is a graded course. May not be included in any of the Biological Sciences concentration programs. (EXPERIENTIAL).

Credits: (3).

Course Homepage: http://www.biology.lsa.umich.edu/~www/bio311/proctor.shtml

Undergraduates who previously have taken an introductory biochemistry course act as TAs for Introductory Biochemistry (Biology 311). TAs meet with the instructor for a two-hour class each week for lectures, presentations, and discussions of teaching and biochemistry. TAs also prepare a report on a recent advance in biochemistry which they present to their peers and the instructor. The major roles of the TAs are to examine the students on their mastery of unit material and to help the students with explanations supplementary to the textbook. At the completion of an instructor-generated written quiz, the student and TA grade the quiz together. TAs learn considerable biochemistry by repeated teachings of unit materials and, in addition, profit from their experience as teachers and evaluators.

Text: Lehninger's Principles of Biochemistry 3rd Edition, Nelson and Cox.

Check Times, Location, and Availability Cost: 1 Waitlist Code: No Data Given.

BIOLOGY 422 / CMB 422. Cellular and Molecular Neurobiology.

Section 001.

Instructor(s): John Y Kuwada (kuwada@umich.edu) , Bruce Oakley (boakley@umich.edu)

Prerequisites & Distribution: Biol. 162, one year of physics, prior or concurrent enrollment in biochemistry. (3). (Excl). (BS).

Credits: (3).

Course Homepage: http://www.biology.lsa.umich.edu/courses/bio422/422home.html

This course deals primarily with the properties of individual nerve cells, and small groups of nerve cells. This provides the basis for understanding information processing by the nervous system, learning and memory, development of neurons, and neurological and psychiatric disorders. Considerable emphasis will be placed on understanding the molecules that endow the nervous system with these properties.

Check Times, Location, and Availability Cost: 3 Waitlist Code: 1

BIOLOGY 423. Introduction to Research in Cellular and Molecular Neurobiology.

Section 001.

Instructor(s): Richard I Hume (rhume@umich.edu)

Prerequisites & Distribution: Concurrent enrollment in Biol. 422; or completion of Biol. 222 or 422, and permission of instructor. (3). (Excl). (BS). Satisfies a Biology laboratory requirement. Laboratory fee ($70) required.

Credits: (3).

Lab Fee: Laboratory fee ($70) required.

Course Homepage: http://biology.lsa.umich.edu/~www/bio423/bio423syl.htm

This lab course provides an introduction to experimental approaches in neurobiology. Emphasis is on molecular, anatomical, and physiological approaches for studying neuronal function. Among the molecular topics to be covered are analysis of cDNA clones, PCR amplification of DNA, and expression of genes in foreign tissues. Among the anatomical topics to be covered are gross and microscopic anatomy of nervous systems, axonal pathway tracing, and immunocytochemical localization of specific neuronal proteins. Among the physiological topics to be covered are intracellular, extracellular and patch clamp recording, as well as the use of computers in the acquisition and analysis of data. This course is intended for students who plan to engage in research in neurobiology.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: 3

BIOLOGY 427. Molecular Biology.

Section 001 Every Student Must Reserve Mondays, Oct. 8, Nov. 12, And Dec. 10, From 6:00-8:00 P.M. For Exams.

Instructor(s): Robert B Helling (helling@umich.edu) , Jianming Li (jian@umich.edu)

Prerequisites & Distribution: Biol. 305; and Biol. 310 or 311, or Biol. Chem. 415. (4). (Excl). (BS).

Credits: (4).

Course Homepage: No Homepage Submitted.

Comprehensive coverage of the general principles governing the structures, synthesis, and functions of DNA, RNA, and proteins in the context of the cell. Emphasizes understanding methods and interpretation of data. Topics include genome organization, DNA replication and transposition, chromosome segregation, transcription and translation, the processing of macromolecules, signal transfer, and regulation at various levels. Two lectures per week are supplemented by a 1.5 hour discussion section.

Check Times, Location, and Availability Cost: 3 Waitlist Code: 1

BIOLOGY 428. Cell Biology.

Section 001 Every Student Must Reserve Mondays, Oct. 8 And Nov. 19, 6:00-8:00 P.M., For Exams.

Instructor(s): Marcus C Ammerlaan (mcammer@umich.edu), Jesse C Hay

Prerequisites & Distribution: Biol. 305; and Biol. 310 or 311, or Biol. Chem. 415. Students with credit for Biol. 320 must obtain permission of instructor. (4). (Excl). (BS).

Credits: (4).

Course Homepage: www.biology.lsa.umich.edu/~www/bio428/index.html

Biology 428 is designed to provide students with a comprehensive overview of the biology of eukaryotes and prokaryotes at the cellular and molecular level. This course is intended for upper-level undergraduates and graduate students. The information is presented at a level that requires students to integrate information from their other biology, chemistry, and biochemistry courses. Topics include: cell structure and function; cell membranes; intracellular organelles and cytoskeleton; inter- and intra-cellular signaling; cell development and cell cycle. Students will be expected to integrate the scientific data presented in class as well as to read and interpret basic research drawn from the current scientific literature. Grades will be based on four exams and the discussion section.

Textbook: Ladish et al. Molecular Cell Biology 4th Edition Freeman Press.

Check Times, Location, and Availability Cost: 1 Waitlist Code: 1

BIOLOGY 436. Introductory Immunology.

Section 001.

Instructor(s): Eric D Mann (ericmann@umich.edu)

Prerequisites & Distribution: Biol. 305 and biochemistry (Biol. 310, 311, or Biol. Chem. 415). (3). (Excl). (BS).

Credits: (3).

Course Homepage: No Homepage Submitted.

This course is intended to introduce pre-professional and biology concentrators to the theoretical and experimental principles of immunology. Topics covered include: a detailed study of the molecules, cells, and organs that constitute the immune system; the innate and adaptive immune responses; and the role of the immune system in host defense, allergy, and organ transplantation. Topics will be illustrated with clinical case studies. Grades are based on three exams. The course is appropriate for concentrations in biology, microbiology, and cell and molecular biology.

Textbook: Janeway et. al. Immunobiology 5th Edition.

Check Times, Location, and Availability Cost: 3 Waitlist Code: No Data Given.

BIOLOGY 440 / NR&E 422. Biology of Fishes.

Section 001.

Instructor(s): William L Fink (wfink@umich.edu), Matthew J Diana

Prerequisites & Distribution: Biol. 162 and one additional biology course. (3). (Excl). (BS).

Credits: (3).

Course Homepage: http://www.umich.edu/~bio440/

Lectures cover many aspects of the biology of lower vertebrates known as fishes, including evolution, physiology, functional morphology, phylogeny, biogeography, ecology, behavior, and reproduction. Much of the course involves participation in the class web site, which should be consulted for a syllabus, descriptions of expectations, and specifics of topics to be discussed. Evaluation of students is based on a take-home midterm exam, a cumulative closed-book final exam, a "capsule" describing the biology of a particular fish species (chosen by the student) for inclusion on the web site, and class participation. All exams consist of essay questions that will require a synthesis of class material, and logic examination of novel problems. An optional laboratory course (Bio 441/NR&E 423) examines field methods, classification, and identification of Michigan fishes.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: No Data Given.

BIOLOGY 441 / NR&E 423. The Biology of Fishes Laboratory.

Section 001.

Instructor(s): Gerald Ray Smith (grsmith@umich.edu)

Prerequisites & Distribution: Biol. 162 and one additional biology course. (1). (Excl). (BS).

Credits: (1).

Course Homepage: www.umich.edu/~bio440/

Optional laboratory course accompanying Biology 440, providing an introduction to the field methods used in fish biology and fisheries, and examining the diversity of the Michigan ichthyofauna and major groups of world fishes.

Check Times, Location, and Availability Cost: 1 Waitlist Code: 1

BIOLOGY 451 / NR&E 451. Biology of Mammals.

Section 001.

Instructor(s): Philip Myers (pmyers@umich.edu)

Prerequisites & Distribution: Biol. 162. (4). (Excl). (BS). Satisfies a Biology laboratory requirement. Laboratory fee ($75) required.

Credits: (4).

Lab Fee: Laboratory fee ($75) required.

Course Homepage: No Homepage Submitted.

Biology 451 introduces students to the diversity of mammals. Through laboratory exercises (one four-hour laboratory period/week) and lectures, participants will have an opportunity to see and learn about species representing all of the major groups of mammals. We will review their evolutionary history; examine adaptations such as those for running, digging, swimming, and flying; and discuss current research in ecology, behavior, zoogeography, and systematics. A text supplements the lectures. Grades will be based on lecture and laboratory exams, participation in discussions, and several brief papers.

Textbook: Vaughan, Ryan, Dzaplewski. 2000 Mammalogy, 4th Edition.

Check Times, Location, and Availability Cost: 1 Waitlist Code: 1

BIOLOGY 459. Systematic Botany.

Section 001.

Prerequisites & Distribution: Biol. 162, or Biol. 255. (4). (Excl). (BS). Satisfies a Biology laboratory requirement. Laboratory fee ($30) required.

Credits: (4).

Lab Fee: Laboratory fee ($30) required.

Course Homepage: No Homepage Submitted.

Plant biodiversity taught with lectures, color projection slides, specimens, living plants, and laboratories. Emphasis at level of orders, families, and genera, temperate and tropical, to familiarize students with plants from all parts of the world. Focuses mainly on flowering plants but also gymnosperms and pteridophytes. Subjects like habitats, endangered species, geography, biosystematics, cladistics, and floral biology are given special lectures. Plant systematics is essential to botanists but the course is needed also by conservationists, ecologists, zoologists, foresters, and ethnobotanists. Some students take the course simply because they enjoy plants. Two midterms, a final, and lab quizzes.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: No Data Given.

BIOLOGY 463. Neotropical Plant Families.

Section 001 A One Week Field Trip To A Tropical Botanical Garden In Florida Will Be Taken.

Instructor(s): Robyn J Burnham (rburnham@umich.edu)

Prerequisites & Distribution: Biol. 215 or Biol. 459. (3). (Excl). (BS).

Credits: (3).

Course Homepage: No Homepage Submitted.

This course will introduce students to generic-level organization of 25 neo-tropical plant families. Families covered will include those that are (1) ecologically widespread and abundant in the neo-tropics (e.g., Fabaceae, Sapindaceae, Bignoniaceae) or (2) of particular taxonomic or economic significance (Lecythidaceae, Annonaceae). Each meeting will include a lecture and slides on the comparative morphology, anatomy, and significance of each family covered, and a laboratory session during which students will be able to examine specimens of each family and to take self-examinations on their ability to apply the characteristics. The course will include, when possible, a week-long field trip to Fairchild Tropical Garden in Miami, Florida, where students will be able to put to good use the training they have gained throughout the course. Guest lecturers will be invited to participate on topics of special interest. The course is intended for advanced undergraduate students and graduate students, both botanists and zoologists (including ecologically oriented students in both disciplines) who have a strong interest in tropical biology. It is expected that students from SNRE as well as LS&A will enroll in the course. There will be two one-hour lectures per week and two one and one-half hour laboratory sessions per week.

Every week a self-exam will be available on which students practice their identification skills. Every two weeks, an exam will be administered that will take less than 30 minutes and will serve as a baseline evaluation of the progress that students are making. A term paper will be required of all participants in which they focus on a large genus or small family of neotropical plants for the purposes of clarifying the phylogenetic relationships, economic or ethnobotanical uses, ecological importance, or biogeography of that small group. Oral presentations of the term papers will take place during the final week of the course.

Textbook: Gentry, A.H. 1996. A Field Guide to Woody Plants of Northwest South America. U. of Chicago Press.

Check Times, Location, and Availability Cost: 2 Waitlist Code: 1

BIOLOGY 477. Laboratory in Field Ecology.

Section 001.

Instructor(s): John H Vandermeer (jvander@umich.edu) , Ivette Perfecto (perfecto@umich.edu)

Prerequisites & Distribution: A course in ecology. (5). (Excl). (BS). Laboratory fee ($30) required.

Credits: (5).

Lab Fee: Laboratory fee ($30) required.

Course Homepage: No Homepage Submitted.

Organizational Meeting, 5 P.M. In 2044 Nat. Sci. On Wednesday, September 5. This Course Will Meet September 14 October 28, Fri. Evenings Beginning At 7 Pm And Concluding Sun. Evenings At 7 Pm.

Ecology students require intensive practice in making field observations and systematically exploring the implications of those observations. One vehicle for doing so is the "field problem" based course, in which a faculty member chooses a general topic and works with a small group of students exploring that topic for an entire day. The field problem-based course is distinct from the laboratory course in that field problems seek to explore an unknown area. The course does not include "set labs" or repeats of well-known patterns. The professor and students seek to explore a specific research question that has not been examined before. The exercise of working through the details of a new problem along with the professor gives the student practice in the creative part of the scientific endeavor. Working with a variety of faculty members the student experiences several "styles" of doing science. The general structure of the course, centered around the field problem, encourages a great deal of discussion among students and between students and faculty. A major goal of the course is to facilitate that discussion. In addition, there is a relatively large lecture load, with an average of four lectures per week.

The Patterson Lake Nature Center is in southeastern Livingston County, approximately 25 miles northwest of Ann Arbor. The Center adjoins the E.S. George Reserve, a University of Michigan research facility. Together the two offer nearly 2,000 acres of protected wildlands, containing a great variety of terrestrial and aquatic habitats all available for research and teaching.

Check Times, Location, and Availability Cost: 1 Waitlist Code: 3

BIOLOGY 480. Computer-Aided Inferences in Evolution and Ecology.

Section 001.

Instructor(s): George F Estabrook (gfred@umich.edu)

Prerequisites & Distribution: Senior natural science concentrator or graduate student. (4). (Excl). (BS).

Credits: (4).

Course Homepage: No Homepage Submitted.

BIO 480 teaches METHODS for formulating hypotheses and for generating predictions from them so that they may be tested with data. These methods will enable you, as a natural scientist, to participate responsibly in the design of your experiments, and in the making of inferences from the data they provide, free of the burden of unwanted mathematical assumptions. In BIO 480, you will learn about basic probability concepts, and how to use them to formulate testable hypotheses to explain natural phenomena. You will learn how to use the PASCAL language to describe your hypotheses so that predictions can be calculated using a personal computer. These predictions take the form of probability distributions. Computationally intense methods such as these avoid the need for inappropriate assumptions and mysterious mathematical techniques, and enable you to understand every step of your own argument.

The course presents 3 hours of explanatory lectures and 2 hours of computer workshops and discussions per week. During the first part of the course, students prepare small weekly projects to present and discuss with each other and the professor. During the second part of the course, each student formulates an hypothesis based on his or her own research project, and simulates predictions.

Check Times, Location, and Availability Cost: 1 Waitlist Code: No Data Given.

BIOLOGY 481. Population Dynamics and Ecology.

Section 001.

Instructor(s): Mercedes Pascual

Prerequisites & Distribution: A course in ecology. Calculus is strongly recommended. (4). (Excl). (BS).

Credits: (4).

Course Homepage: No Homepage Submitted.

An examination of the principles of population ecology. Theoretical and empirical research on population dynamics and regulation of managed and natural populations are emphasized, as well as the development of the mathematical and computer skills for modeling dynamics of single and interacting populations. Specific topics include concepts of linear and nonlinear dynamics, demography, life history evolution, density-dependence and population regulation, and basic models of competition, mutualism, predator-prey, host-disease, and other population interactions. A background in ecology or permission of the instructor is required. There will be two 1.5 hour lectures and one two hour discussion section a week. Discussion sections will cover original readings from the literature and techniques for modeling populations. Course requirements include computer modeling projects and writeups, a midterm, and a final.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: No Data Given.

BIOLOGY 498. The Ecology of Agroecosystems.

Section 001.

Instructor(s): John H Vandermeer (jvander@umich.edu)

Prerequisites & Distribution: A course in ecology. (3). (Excl). (BS).

Credits: (3).

Course Homepage: No Homepage Submitted.

An analysis of ecological principles as they apply to agricultural ecosystems, emphasizing theoretical aspects but also covering empirical results of critical experiments. While the emphasis is on principles, practical applicability is also explored where appropriate. Physical, biological, and social forces will be integrated as necessary. Designed as preparation for active research in agroecosytem ecology.

Check Times, Location, and Availability Cost: 1 Waitlist Code: No Data Given.

BIOLOGY 514. Topics in Molecular Evolution.

Section 001 Comparative DNA/Amino Acid Sequence Analysis.

Instructor(s): Priscilla Tucker (ptuck@umich.edu)

Prerequisites & Distribution: Biol. 305 and one upper-level course in either molecular or evolutionary biology, and permission of instructor. (3). (Excl). (BS).

Credits: (3).

Course Homepage: No Homepage Submitted.

The subject of this course is methods of comparative DNA/amino acid sequence analysis using an evolutionary approach. Topics of sequence alignment and phylogeny reconstruction using DNA and protein sequences are covered.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: No Data Given.

BIOLOGY 521. Bacterial Physiology II: Carbon Metabolism.

Section 001 This Course Will Meet Oct. 9 Nov. 6.

Instructor(s): Robert A Bender (rbender@umich.edu)

Prerequisites & Distribution: Biol. 305, and Biol. 310 or 311 or Biol. Chem. 415. (1). (Excl). (BS).

Mini/Short course

Credits: (1).

Course Homepage: No Homepage Submitted.

This course will focus on central metabolism especially the catabolism of glucose, lactose, and amino acids. Among the topics considered will be: (1) "The memory paradox" where bacterial cells remember how they were grown 40 generations ago in the absence of external reminder; (2) the integration of pathways and how changes in one effect the flow of another; and (3) global regulators (known and unknown) that integrate complex signals and transmit them into gene expression responses. Biochemistry shows that pathways exist, physiology asks the questions of how they function and why they are important. The key theme of the course will be regulation rather than memorizing pathways.

Bacterial Physiology II is entirely independent of the related Bacterial Physiology I and III courses and can be taken without either of the others.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: No Data Given.

BIOLOGY 522. Bacterial Physiology III: Nitrogen Metabolism.

Section 001 This Course Will Meet Nov. 8 Dec. 11.

Instructor(s): Robert A Bender (rbender@umich.edu)

Prerequisites & Distribution: Biol. 305, and Biol 310, 311, or Biol. Chem 415. (1). (Excl). (BS).

Mini/Short course

Credits: (1).

Course Homepage: No Homepage Submitted.

This course will focus on the interconversion of various kinds of nitrogen sources. Topics will include the reduction of nitrate and atmospheric nitrogen to ammonia and the catabolism of urea and amino acids. Emphasis will be on the regulation of these pathways and the regulatory features that allow cells to use only the "appropriate" nitrogen sources to supply their needs. For example, how does a cell know to use the urea before porline as a nitrogen source (and ammonia before urea)? The key theme of the course will be regulation and the logical methods used to figure out how regulation functions.

Bacterial Physiology III is entirely independent of the related Bacterial Physiology I and II courses and can be taken without either of the others. The course is intended for graduate students and upper class undergraduates with an interest in microbiology or biochemical regulation.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: No Data Given.

BIOLOGY 525 / Chem. 525. Chemical Biology I.

Section 100.

Prerequisites & Distribution: Chemistry 451, 452, 461, and 463. (3). (Excl). (BS).

Credits: (3).

Course Homepage: No Homepage Submitted.

See Chemistry 525.001.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: No Data Given.

Graduate Course Listings for BIOLOGY.


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