Fall '99 Course Guide

Courses in Biology (Division 328)

Fall Term, 1999 (September 8 December 22, 1999)

Take me to the Fall Term '99 Time Schedule for Biology.


Biol. 100. Biology for Nonscientists.

Section 001 Primarily A Distribution Course. Not Intended for Students Who Plan to Concentrate in Biology Or Other Science Programs

Instructor(s): Karen Ocorr (kocorr@umich.edu), Marcy Osgood (mosgood@umich.edu)

Prerequisites & Distribution: Not open to those with Advanced Placement or "Departmental" credit in biology, nor to those concentrating in the biological sciences. Credit is granted for a combined total of 12 credits elected in introductory biology. (4). (NS). (BS).

Credits: (4).

Course Homepage: No Homepage Submitted.

Biology 100 is a one-term course designed to introduce students to current biological concepts. The course consists of three hours of lecture per week plus a coordinated discussion session which occupies two hours per week. Biology 100 provides an introduction to some general principles of biology and concentrates on the areas of cell biology, genetics, evolution, and environmental biology. A major objective of this course is to point out to students the nature of the scientific process and illustrate the uses and non-uses of science in contemporary life. Wherever possible, the ethical and social implications of contemporary scientific effort will be discussed. This course is designed for students with a minimal background in the biological sciences, but we do assume some exposure to biology at the high school level. Discussion sections enroll 20 students and are taught by graduate student instructors. In the discussion section, students have the opportunity to review material presented in lecture and participate in discussions of issues raised in the lecture segment.

Check Times, Location, and Availability Cost: 3 Waitlist Code: 1; you MUST attend the first discussion section to claim your place in the course

Biol. 101. Biology and Human Affairs.

Section 001.

Instructor(s): John Vandermeer (jvander@umich.edu) , Mark Wilson (wilsonml@umich.edu)

Prerequisites & Distribution: Credit is granted for a combined total of 12 credits elected in introductory biology. (4). (NS). (BS).

Credits: (4).

Course Homepage: No Homepage Submitted.

This course is an introduction to those aspects of biology that have direct applicability to the lives of people in today's world. It covers current controversies within biology, especially as they relate to human life and human affairs. Topics discussed include race, health, and the environment. Background information is given for each topic, but the emphasis is placed on the controversies and the role of science in human affairs. In addition to the two lectures per week, there is a two-hour discussion period in which the topics are further explored and films are frequently shown.

Check Times, Location, and Availability Cost: 3 Waitlist Code: 1

Biol. 110/AOSS 171/UC 110/NR&E 110. Introduction to Global Change I.

Section 001.

Instructor(s): Timothy Killeen (tkilleen@umich.edu)

Prerequisites & Distribution: Credit is granted for a combined total of 12 credits elected in introductory biology. (4). (NS). (BS).

Credits: (4).

Course Homepage: http://www.globalchange.umich.edu/

Have you ever considered the future consequences of current stresses being put on Earth's environment by humankind's consumption and pollution patterns? Are you interested in discussing critical issues relating to the role of international business, resource economics, human development, and the individual person's responsibility in global change? Funded by grants from NASA and The National Science Foundation, Introduction to Global Change I is an interdisciplinary team-taught introduction to the evolution of the physical Earth and the evolution of life and the human species on our planet. You'll gain state-of-the-art knowledge from some of America's foremost scholars in space physics, biology, geology and Earth ecology. The Web-based course curriculum provides unparalleled opportunities to conduct on-line Internet research. You will even create your own home-page. The interactive laboratory exercises provide you the opportunity to use computers to examine how natural systems function as well as develop projections of the future consequences of the stresses being put on the environment. You will use multi-media tools for graphing and computer researching. And, perhaps most important of all, you will have ample time for discussion of the critical issues in human development and how they relate to the international business community, society as a whole and the individual in global change. All topics are developed in a manner that students will find both accessible and enjoyable. The course grade is based on two midterm exams, a final exam, completion of laboratory modules, and a course poster project based on some aspect of global change. There are no prerequisites for the course and no science background is assumed. The course is appropriate for all undergraduate students, irrespective of intended concentration.

You will learn about...

The Universe:

  • Big Bang Theory
  • Birth and Death of Stars
  • Radiation Laws
  • Origin of the Elements

Our Planetary System:

  • Primitive Atmospheres
  • The Age of the Earth
  • Continental Drift
  • Chemical & Biological Evolution
  • The Building Blocks for Life

Earth's Atmospheric & Oceanic Evolution:

  • Life Processes and Earth Systems
  • The Great Ice Ages
  • Atmospheric Circulation
  • Climate and Paleoclimate
  • Greenhouse Gases and Global Warming
  • Sea Level Changes
  • El Niño

The Tree of Life:

  • Emergence of Complex Life
  • Extinction and Radiation
  • The Five Kingdoms
  • Natural Selection
  • Respiration and Photosynthesis
  • Ecosystems

Projected Ecological Consequences:

  • Elevated Carbon Dioxide Levels
  • Environmental Pollutants
  • Ozone Depletion
  • Likelihood of Global Climatic Change

You will discuss...

  • The Role of the Individual as a Citizen of the Planet
  • Case Studies of Regional and Global Change Issues
  • The Historical Context for Current and Projected Global Change

You will create...

  • Models of Interacting Systems that Give Insight into the Collision Between Natural and Societal Processes

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: No Data Given.

Biol. 120. First Year Seminar in Biology.

Section 001 Emerging and Re-Emerging Infectious Diseases

Instructor(s): Alice Reinarz (areinarz@umich.edu)

Prerequisites & Distribution: Only first-year students, including those with sophomore standing, may pre-register for First-Year Seminars. All others need permission of instructor. (3). (NS). (BS).

First-Year Seminar

Credits: (3).

Course Homepage: No Homepage Submitted.

During the age of discovery of antibiotics, medical scientists often expressed confidence in winning the "War on Disease." Microbes have prevailed, however, and recent news is filled with accounts of recurring and previously unknown threats. This seminar will examine clinical victories and failures to contain infectious diseases. Models will include polio, influenza, HIV infections, multi-drug resistant tuberculosis, and Ebola. This course is limited to 20 first-year students. The class will be primarily discussion format and will include oral presentations by students. The grade will be based on class discussion, group presentation, and written assignments.

Check Times, Location, and Availability Cost: 1 Waitlist Code: No Data Given.

Biol. 140. Genetics and Society.

Section 001.

Instructor(s): Julian Adams (julian@umich.edu)

Prerequisites & Distribution: Credit is granted for a combined total of 12 credits elected in introductory biology. (4). (NS). (BS).

Credits: (4).

Course Homepage: No Homepage Submitted.

This introduction to the impact of modern genetics on society is designed for students not concentrating in the sciences. Students will gain a background in genetics that should enable them to: (1) understand and evaluate reports on the latest advances in genetics that appear in the media; (2) be able to discuss the social history of genetics; (3) have a better appreciation of the "scientific method;" and (4) discuss aspects of genetics that have a bearing on our daily lives. There will be three lectures and a discussion group per week, with topics such as human diversity; genetics and medicine, including cancer, AIDS, and complex diseases; gene therapy; DNA and forensic analysis; technological and economic applications of genetics; and biological determinism. Course evaluation is mainly based on a flexible combination of short-answer exams and a term paper.

Check Times, Location, and Availability Cost: 1 Waitlist Code: 1

Biol. 162. Introductory Biology.

Section 001 This Course is Intended for Students Planning to Concentrate in Biological or Other Science Programs, Including Premedical Programs. Every Student Must Reserve Mondays, 6-8 P.M. for Exams. Honors Students Elect Lecture Section 002 and Either Section 009 Or 013. Sections 031 and 035 are Reserved for Students in the Comprehensive Studies Program. Enrollment is Only By Permission of A CSP Advisor. Inquire in G155 Angell Hall for Further Information

Instructor(s): John Schiefelbein (schiefel@umich.edu)

Prerequisites & Distribution: Prior or concurrent enrollment in Chemistry 130. Biology 162 is not open to students who have completed Biol. 152, 154 Or 195. Credit is granted for a combined total of 12 credits elected in introductory biology. (5). (NS). (BS). Laboratory fee ($68) required.

Credits: (5).

Lab Fee: Laboratory fee ($68) required.

Course Homepage: No Homepage Submitted.

A one-term introductory course intended for concentrators in biology, other science programs, or preprofessional studies. Other suitably prepared students wishing detailed coverage of biology are also welcome. The aims of Biology 162 are: (1) to provide factual and conceptual knowledge; (2) to give an integrated overview of the central tenets of modern biology; (3) to afford experience in obtaining and interpreting biological hypotheses; and (4) to develop thinking and writing skills. Topics in Biology 162 are divided among four areas: (a) cellular and molecular biology; (b) genetics; (c) evolution; and (d) ecology. Students MUST: (1) attend 3 lectures, 1 one-and-a-half hour discussion, and 1 three hour lab section each week; (2) ATTEND THEIR ASSIGNED DISCUSSION AND LAB MEETINGS EACH WEEK STARTING WITH THURSDAY DISCUSSIONS IN THE FIRST WEEK OR THEIR SPACE MAY BE GIVEN TO SOMEONE ON THE WAITING LIST; and (3) RESERVE the times and dates for the midterm and final exams (as specified in the Time Schedule) before enrolling. Students usually purchase a textbook, lab manual, and course pack consisting of a syllabus and lecture notes. No other study guides or supplementary materials need be bought. For Honors credit, register for one of the Honors discussion/lab sections. For further information contact the Introductory Biology office, 1039 Chemistry Building (764-1430).

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: 5 If A Section you want is filled, place your name on the Waitlist maintained in 1039 Chemistry, 764-1430.

Biol. 200. Undergraduate Tutorial.

Instructor(s):

Prerequisites & Distribution: Permission of faculty member in biology. (2). (Excl). (BS). (INDEPENDENT). May be repeated for a total of six credits.

Credits: (2).

Course Homepage: No Homepage Submitted.

This course is intended for sophomores learning research and laboratory techniques, working under close supervision of a faculty member. It may also be used for directed readings at an appropriate level. It includes reading on a significant topic and regular consultation with the faculty member chosen to supervise the work. The required paper could be on the scientific literature in a broad field, on biological issues on which the student may want to do continuing work, or on the detailed results of research in a biological specialty. Conferences, seminars, readings, and assigned writings are used to develop critical perspectives on modern biological problems and to provide breadth and sense of historical continuity in biological thought.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: No Data Given.

Biol. 201. Introduction to Research in the Life Sciences.

Section 001.

Instructor(s):

Prerequisites & Distribution: Grade of B+ or better in Biology 162 (or 152 or 154). (1). (Excl).

Credits: (1).

Course Homepage: No Homepage Submitted.

This course is designed to help students identify potential mentors for independent lab or field research. This course is particularly appropriate for students in Biology 162 or 305, 310, or 311 who hope to join the junior/senior Honors Program of the Biology Department. Membership in the LS&A freshman-sophomore Honors Program is not required. This course will introduce students to the diversity of research opportunities and approaches to research in the biological sciences that are available on the Michigan campus, by having a variety of scientists who sponsor undergraduate research visit the class. About 2/3 of the visiting scientists will be from the Department of Biology, while the rest will be from the Medical School and other schools at the University of Michigan. Students in the class will be evaluated based on two short papers, an oral presentation to the class, and on their participation in class discussion. Weekly reading assignments will form the basis of class discussion.

Check Times, Location, and Availability Cost: 1 Waitlist Code: 1

Biol. 207. Introductory Microbiology.

Anatomy, Physiology, and Development

Section 001.

Instructor(s): Eric Mann (ericmann@umich.edu)

Prerequisites & Distribution: Biol. 162 (or 152). (4). (NS). (BS). Satisfies a Biology laboratory requirement. Laboratory fee ($70) required.

Credits: (4).

Lab Fee: Laboratory fee ($70) required.

Course Homepage: No Homepage Submitted.

The course consists of three one-hour lectures and one three-hour laboratory session each week. The lectures will trace the history of microbiology, microbial growth and metabolism, microbial diversity, and the importance of microbes in the environment, industry, and medicine. The laboratory sessions introduce microscopy, aseptic technique, staining, and the isolation, culture, and identification of microbes from the local environment. Grades are based on two lecture exams, a grant proposal, and the identification of unknown bacteria. The course is required for the microbiology concentration program, and is appropriate for the biology concentration.

Check Times, Location, and Availability Cost: 3 Waitlist Code: 1

Biol. 208. Embryology.

Anatomy, Physiology, and Development

Section 001.

Instructor(s): Kathryn Tosney (ktosney@umich.edu)

Prerequisites & Distribution: Biology 162. (3). (NS). (BS).

Credits: (3).

Course Homepage: No Homepage Submitted.

In this Embryology course, we will study the entire organism as a function of time. We will seek to understand how a single cell, the fertilized egg, develops through time to form a multicellular organism. We will study the early stages of development, when cells divide and form the basic structures in the right places, establishing the basic body plan for each individual and initiating the development of different cell types. We will study the embryo as it progresses through stages of cleavage, blastula formation, gastrulation, and organogenesis. We will maintain a focus on human development, but we will use animal models to understand developmental concepts such as differentiation, determination, epigenesis, and axis formation. Another goal is to develop conceptual and analytical skills, particularly the abilities to select and analyze information critically, to pose problems proficiently, to solve problems perceptively, to communicate persuasively, and to work as an effective part of a team. The course will combine lectures with facilitated peer-learning sessions and computer-intensive exercises.

Check Times, Location, and Availability Cost: 2 Waitlist Code: 1

Biol. 222. From Message to Mind: An Introduction to Neurobiology.

Anatomy, Physiology, and Development

Section 001.

Instructor(s): Stephen Easter (sseaster@umich.edu)

Prerequisites & Distribution: Biol. 162 (or 152-154) or 195. (3). (Excl). (BS).

Credits: (3).

Course Homepage: No Homepage Submitted.

An introduction to molecular, cellular, and systems-level neurobiology. Topics include: (1) bioelectricity; (2) intercellular communication; (3) sensory transduction and processing; (4) motor function; and (5) the neural basis of simple behaviors. Students will be evaluated by exams, papers, and participation in discussion.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: 1

Biol. 225(325). Principles of Animal Physiology: Lecture.

Anatomy, Physiology, and Development

Section 001.

Instructor(s): Robert Denver (rdenver@umich.edu) , Cunming Duan (cduan@umich.edu)

Prerequisites & Distribution: Biol. 162 and a year of chemistry. No credit granted to those who have completed or are enrolled in Biol. 420. (3). (Excl). (BS).

Credits: (3).

Course Homepage: No Homepage Submitted.

This course is an introduction to the physiological view of animals and emphasizes zoological rather than human aspects. The course uses evidence from different groups of organisms to identify the general principles of functional mechanisms. It also considers variations in these mechanisms as related to the requirements of the animals but does not attempt a phylogenetic survey. The course is intended for concentrators and pre-medical students in their sophomore, junior, or senior years. The subject matter includes metabolism and temperature regulation, nervous and endocrine system controls and integration, respiration and circulation, water and ion balance, excretion, digestion, reproduction, and immune system function. There are three 1-hour lectures a week, three 1-hour examinations, and a final exam.

Check Times, Location, and Availability Cost: 3 Waitlist Code: 1

Biol. 226(326). Animal Physiology Laboratory.

Anatomy, Physiology, and Development

Instructor(s):

Prerequisites & Distribution: Concurrent enrollment in Biol. 225 (or prior enrollment in 325, with permission). Students who have taken or intend at a later date to take Biol. 225 will not be admitted to Biol. 226 without special permission. (2). (Excl). (BS). Satisfies a Biology laboratory requirement. Laboratory fee ($70) required.

Credits: (2).

Lab Fee: Laboratory fee ($70) required.

Course Homepage: No Homepage Submitted.

These laboratory exercises deal (usually concurrently) with topics covered in the lecture. The laboratory meets for one four-hour session a week. Students working in small groups present material for each exercise, collate class data, and perform analyses. A term paper and oral presentation are required. Students should have had Biology 225 (325) or be taking it concurrently.

Check Times, Location, and Availability Cost: 2 Waitlist Code: 1

Biol. 230. Introduction to Plant Biology.

Section 001.

Instructor(s): Larry Noodén (ldnum@umich.edu)

Prerequisites & Distribution: Biol. 162 (or 152) or 195. (4). (NS). (BS). Laboratory fee ($65) required.

Credits: (4).

Lab Fee: Laboratory fee ($65) required.

Course Homepage: No Homepage Submitted.

This course will provide a broad, integrated overview of plant biology including economic and environmental aspects. The general areas covered are: (1) Plant diversity the basic biology and evolution of the bacteria, fungi, algae, plantimals, bryophytes, and vascular plants. In addition, special aspects such as their environmental impacts, toxicology, cell biology, and molecular evolution will be covered. (2) Structure, function, and development from the cell-molecular level to the whole organism. Photosynthesis, internal transport, hormones, environmental controls, molecular biology, genetic engineering, and biotechnology will be included. (3) Ecology, adaptations to their environment, plant-animal interactions, ethnobotany, plant medicinals, biomes, biogeography, and evolution. Students will also work with the Internet and electronic databases to answer questions in the course subject area. In addition to two hrs/week of lecture, there will be a discussion (one hr/week) and a lab (three hrs/week) with two field trips. Evaluations will be based on 2 one-hour exams, a final exam, four lab quizzes and two short papers. Students will have to purchase a textbook, lab manual, and a course pack consisting of a syllabus and some illustrations. This course is not open to those who have completed Biology 154.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: No Data Given.

Biol. 252. Chordate Anatomy and Phylogeny.

Anatomy, Physiology, and Development

Section 001.

Instructor(s): William Fink (wfinnk@umich.edu)

Prerequisites & Distribution: Biol. 162 (or 152-154) or 195. (4). (Excl). (BS). Satisfies a Biology laboratory requirement. Laboratory fee ($60) required.

Credits: (4).

Lab Fee: Laboratory fee ($60) required.

Course Homepage: No Homepage Submitted.

This course teaches the comparative method, using the "three-fold parallelism" of anatomy, ontogeny, and paleontology. All examples are based on chordate animals, with emphasis on their anatomy and development. The introductory third of the course includes the theoretical basis of the comparative method, principles of evolutionary theory and speciation, and phylogenetics. The remainder of the course involves application of the method, with a survey of chordate structure, including the integument, skeleton, muscles, and the circulatory, urogenital, digestive, respiratory, and nervous systems. The laboratory provides practical experience in the comparative method, including dissections. There are three one-hour lectures per week and one three-hour laboratory. There are two hourly examinations and a final examination for the lecture, and a one-hour laboratory practical exam. A detailed syllabus and laboratory manual, rather than an assigned textbook, are used.

Check Times, Location, and Availability Cost: 1 Waitlist Code: 1

Biol. 281. General Ecology.

Ecology and Population Biology

Section 001.

Instructor(s): Beverly Rathcke (brathcke@umich.edu), Earl Werner (eewerner@umich.edu)

Prerequisites & Distribution: Biol. 162 (or 152 and 154) and a laboratory course in chemistry. No credit granted to those who have completed or are enrolled in Biol. 381. (3). (NS). (BS).

Credits: (3).

Course Homepage: No Homepage Submitted.

The course introduces the basic concepts and principles of ecology as applied to the study of individuals, populations, and communities of both plants and animals. Course topics include the roles of physical and biotic factors influencing the distribution and abundance of organisms, the dynamics of population growth, species interactions including competition, predation, mutualism, the structure of ecological communities, ecological succession, and applications of ecology to problems of environment and resource management. Biology 281 is a suitable prerequisite for intermediate and advanced courses in ecology. There will be lectures, discussions, and computer simulations. Three exams will constitute the main basis of evaluation.

Check Times, Location, and Availability Cost: 2 Waitlist Code: 1

Biol. 282. General Ecology Laboratory.

Ecology and Population Biology

Section Free University Bus to Botanical Gardens Leaves from Rackham Bldg. At 8:00 AM. and 1:00 PM. and Returns At Noon and 5:00 PM. No Credit for this Course is Granted to Those Who Have Completed Biol.381

Instructor(s): Beverly Rathcke (brathcke@umich.edu)

Prerequisites & Distribution: Biol. 162 (or 152 and 154), a laboratory course in chemistry, and concurrent or prior enrollment in Biol. 281. (3). (Excl). (BS). Laboratory fee ($70) required.

Credits: (3).

Lab Fee: Laboratory fee ($70) required.

Course Homepage: No Homepage Submitted.

This laboratory course introduces the basic concepts and methods used in ecological research. The laboratories consist of both field and laboratory research projects, field trips, computer simulations, and an independent research project that is designed by each student. Students will write up laboratory reports and a paper on their independent research, give an oral presentation on their independent research, and participate in laboratory discussions.

Check Times, Location, and Availability Cost: 1 Waitlist Code: 1

Biol. 300. Undergraduate Research.

Instructor(s):

Prerequisites & Distribution: Eight credits of biology and 3.0 grade point average in science; permission of faculty member in biology. (1-3). (Excl). (BS). (INDEPENDENT). May be repeated for a total of 9 credits.

Credits: (1-3).

Course Homepage: No Homepage Submitted.

Intended primarily for juniors, including Honors students, who wish to pursue independent research or study at an intermediate level in an area of biological science. The student may ask an appropriate faculty member in the Department of Biology to direct the research project and supervise related readings. The project may take the form of an investigation of new problems in the field or laboratory, a detailed investigation of primary sources (a literature survey), development of new procedures or programs, design of a classroom experiment, etc. A final paper is required and must be approved by the research advisor.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: No Data Given.

Biol. 302. Teaching Experience for Undergraduates.

Instructor(s):

Prerequisites & Distribution: Permission of instructor. (1-3). (Excl). May not be included in any of the Biological Sciences concentration programs. (EXPERIENTIAL).

Credits: (1-3).

Course Homepage: No Homepage Submitted.

Undergraduates participating in this course are responsible for (1) aiding regularly assigned Graduate Student Instructors; (2) providing tutorial help for undergraduates enrolled in the course; (3) meeting regularly with discussion and laboratory sessions; and (4) participating with Graduate Student Instructors in instructional activities.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: No Data Given.

Biol. 305. Genetics.

Section 001 Exams Will be Held Mondays, Sept 27, Oct 18, and Nov 15, 6-8pm.

Instructor(s): Wesley Brown (wbrown@umich.edu)

Prerequisites & Distribution: Biol. 162 (or 152) or 195. Prior or concurrent enrollment in Biol. 310, 311, or Biol. Chem. 415, or Chem. 451. (4). (Excl). (BS).

Credits: (4).

Course Homepage: No Homepage Submitted.

This course is intended for students who are concentrating in the natural sciences, or who will apply for graduate or professional study in the biological sciences. The material is divided into two sections: classical studies of how genes are transmitted; and molecular studies of gene structure and regulation. There are three hours of lecture each week, and one discussion section directed by a graduate student instructor. The discussion sections are used to review and expand on lecture material, and to discuss problem assignments. Grading is based on examinations covering both lecture material and problem assignments.

Check Times, Location, and Availability Cost: 2 Waitlist Code: 1

Biol. 306. Introductory Genetics Laboratory.

Molecular and Cellular Biology

Section 001.

Instructor(s): Santhadevi Jeyabalan (sjeyabal@umich.edu)

Prerequisites & Distribution: Prior or concurrent enrollment in Biol. 305. (3). (Excl). (BS). Satisfies a Biology laboratory requirement. Laboratory fee ($70) required.

Credits: (3).

Lab Fee: Laboratory fee ($70) required.

Course Homepage: No Homepage Submitted.

This course provides students with laboratory experience on basic genetic principles. Students will analyze patterns of inheritance, gene interaction, linkage relationship, and genetic mapping of unknown mutants of Drosophila through a series of genetic crosses. By using molecular techniques such as Polymerase Chain Reaction (PCR) and gel electrophoresis, mutations in Caenorhabditis elegans will be mapped to chromosomal locations. The experiments in microbial genetics include mapping by conjugation in E. coli, recombination analysis by transduction using bacteria and phage, and complementation tests on "his" mutants of yeast. Experiments in Human Population Genetics include calculating allelic frequencies of PTC tasting in the class. Students will also be doing DNA fingerprinting of a VNTR locus using their own squamous epithelial cells. One hour lecture on Mondays 1-2 PM and one three-hour lab are scheduled each week; additional 3-4 hours of lab time per week is expected at irregular times. Students are expected to write one formal lab report and to keep a complete and accurate record of all results and analyses in a bound lab notebook. There are two tests given during the term.

Check Times, Location, and Availability Cost: 1 Waitlist Code: 1

Biol. 310. Introductory Biochemistry.

Section 001.

Instructor(s): Karen Ocorr (kocorr@umich.edu)

Prerequisites & Distribution: Biol. 162 (or 152) or 195; and organic chemistry. No credit granted to those who have completed or are enrolled in Biol. 311, Biol. Chem. 415, or Chem 451. (4). (Excl). (BS).

Credits: (4).

Course Homepage: http://biology.lsa.umich.edu/~www/bio310/

Introductory Biochemistry is designed to be a general introduction to the chemistry of biological systems. The biweekly lectures for this course cover basic information on biomolecules and the organization of chemical reactions in cells. Students are also exposed to the strategies used by cells and multicellular organisms to coordinate the activity of various metabolic pathways. Topics covered include: protein structure and function; enzyme kinetics; intermediary metabolism; photosynthesis; transcription; translation; and the hormonal regulation of metabolism. In addition to the lectures, there is a weekly discussion session which has a project-based format. Students are provided with an opportunity to become more actively involved in their own learning experience. Students will have the chance to further explore the relationship between Biochemistry and the world around them through weekly mini-presentations. A variety of weekly projects are designed to help students master the material using the Internet, scientific literature, etc. Discussion sessions are informal, allowing students ample opportunity to discuss the lecture topics and ask questions. There is an extensive web site for this course providing students with numerous additional resources to help them master the material (http://biology.lsa.umich.edu/~www/bio310/). Grades in this course are based on performance in the discussion session (20%), two in-class exams (50%), and a final exam (30%).

Check Times, Location, and Availability Cost: 2 Waitlist Code: 1

Biol. 311. Introductory Biochemistry.

Section 001 Orientation Meeting Wed., Sept. 8, 6:00- 7:00 pm NatSci Aud. Self-Paced, Personalized System of Instruction. Optional Lectures on Thursdays from 12-1 pm., in 4140 Nat. Sci. Midterm Exam Wed., Oct. 20, 6:00 9:00 pm. Final Exam Wed., Dec. 15, 6:00 9:00 pm

Instructor(s): Marcy Osgood (mosgood@umich.edu)

Prerequisites & Distribution: Biol. 162 (or 152) or 195; and organic chemistry. No credit granted to those who have completed or are enrolled in Biol. 310, Biol. Chem. 415, or Chem 451. (4). (Excl). (BS).

Credits: (4).

Course Homepage: http://www.biology.lsa.umich.edu/courses/bio311/

This course is taught by a self-paced, personalized system of instruction. Students interact, according to their own schedules, with undergraduate TA's. The student takes both a written and an oral quiz for each of 12 units which is graded and evaluated by the TA. If mastery is attained, the student may proceed to the next unit. Grades are assigned according to the number of units successfully completed and performance on the midterm and final examinations. This system is designed to take into consideration different rates of individual learning as well as to eliminate competition among students. TA's are available approximately 75-80 hours/week.

Check Times, Location, and Availability Cost: 3 Waitlist Code: 1

Biol. 324(224). Biology of Cancer.

Molecular and Cellular Biology

Section 001.

Instructor(s): Lewis Kleinsmith (lewisk@umich.edu)

Prerequisites & Distribution: Biol. 162. No credit granted to those who have completed or are enrolled in Biol. 124. (3). (NS). (BS).

Credits: (3).

Course Homepage: No Homepage Submitted.

The Biology of Cancer is a lecture/discussion course designed to provide students with a basic understanding of the biological events associated with the development of cancer. This course is organized around three fundamental questions: What is cancer; what are the causes of cancer; and can cancer be cured or prevented? Lectures will include descriptions of classical and recent experiments which address these questions, and will also provide students with the vocabulary and background needed to critically read and evaluate technical literature dealing with the subject of cancer. Student performance will be evaluated by a combination of exams and a term paper based upon library research. In order to provide the time required for this library research, the lecture-discussion meetings will be dismissed for approximately one week late in the term. There will be no assigned textbook, but some reading will be assigned from the course pack. The class will meet twice a week for an hour and a half; in general, meetings will consist of a one hour lecture followed by questions and discussion. A weekly hour and a half discussion session will also be held.

Check Times, Location, and Availability Cost: 1 Waitlist Code: No Data Given.

Biol. 355/NR&E 337. Woody Plants I: Biology and Identification.

Biological Evolution and Diversity

Section 001 Meets with NR&E 437.

Instructor(s): Warren Wagner (whwag@umich.edu)

Prerequisites & Distribution: Biol. 162 (or 152) or 195. (4). (Excl). (BS). Satisfies a Biology laboratory requirement. Laboratory fee ($45) required.

Credits: (4).

Lab Fee: Laboratory fee ($45) required.

Course Homepage: No Homepage Submitted.

The identification of trees, shrubs, and vines is the basis for the study of their biology and ecology. Woody plants are studied in their natural ecosystems including upland (oak-hickory, beech-sugar maple, lake plain), wetland (swamp, bog), and floodplain forests. Non-native species and ornamental plants are taught in the Saginaw Forest, Stinchfield Woods, Nichols Arboretum, and main campus. An introduction to the biology and ecology of woody plants is given in lectures. Topics include vegetative and reproductive morphology; woody plant biology, ecology, and diversity; variation and genetics; systematics of woody plants; ornamental plants; and winter conditions. Also discussed are important trees of southern and western U.S., China, and the tropics. Field trips are scheduled from 1:00 to 6:00 once a week. Michigan Trees (Barnes and Wagner) is the required textbook. Grading is based on 60% on plant identification (field quizzes and exams and indoor identification exams); 40% on lecture material (two hour-exams).

Check Times, Location, and Availability Cost: 1 Waitlist Code: 2, at SNRE Office of Academic Programs, 1024 Dana

Biol. 380. Oceanography: Marine Ecology.

Biological Evolution and Diversity

Section 001.

Instructor(s): John Lehman (jtlehman@umich.edu)

Prerequisites & Distribution: Biol. 162 (or 152-154) or 195, and at least one term of college chemistry or physics. (3). (Excl). (BS).

Credits: (3).

Course Homepage: No Homepage Submitted.

Marine ecology is a study of the organisms and processes of the ocean, including both water and sediment communities. This course teaches physical and chemical aspects, but emphasizes biological aspects of oceanography, and applies ecological and evolutionary principles to the study of marine life. Lectures introduce the major groups of marine organisms and cover the interrelationships of marine organisms and their environments. Organisms and communities from the following habitats are discussed: estuaries; the rocky intertidal; coral reefs; the coastal zone; the deep sea; and the open ocean. The course treats organisms as different as bacteria and whales. This course is required for the Marine Biology option of the undergraduate Oceanography concentration. Grading is based on two one-hour exams plus a comprehensive final.

Check Times, Location, and Availability Cost: 2 Waitlist Code: 3

Biol. 390. Evolution.

Biological Evolution and Diversity

Section 001.

Instructor(s): Brian Hazlett (bhazlett@umich.edu)

Prerequisites & Distribution: Biol. 162 (or 152-154). (4). (Excl). (BS).

Credits: (4; 5 in the half-term in Ann Arbor; 5 at Biol. Station).

Course Homepage: No Homepage Submitted.

This lecture course covers the fundamentals of evolutionary biology with a focus on living organisms. It includes a historical survey of the development of evolutionary theory from ancient philosophers to the present, and critical examination of phylogenetic systematics, natural selection, population genetics, molecular evolution, microevolution, and macroevolution. Weekly discussions will focus on primary literature. Two midterm tests and one cumulative final exam will test students' knowledge of lecture material. Writing assignment(s) based on readings from the primary scientific literature will be required.

Check Times, Location, and Availability Cost: 2 Waitlist Code: 1

Biol. 400. Advanced Research.

Instructor(s):

Prerequisites & Distribution: 12 credits of biology, 3.0 average in science, and permission of faculty member in biology. (1-3). (Excl). (BS). (INDEPENDENT). May be repeated for a total of 9 credits.

Credits: (1-3).

Course Homepage: No Homepage Submitted.

Intended for those engaged in original research at an advanced level. This course number is most frequently elected by senior Honors students who have completed Biology 300 and who are completing their research and writing their thesis. A final paper is required. (Refer to the description of Biology 300 for more information.)

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: No Data Given.

Biol. 406. Molecular Genetics of Plant Development.

Molecular and Cellular Biology

Section 001.

Instructor(s): Steven Clark (clarks@umich.edu)

Prerequisites & Distribution: Biochemistry (Biol. 310, 311, or Biol. Chem. 415), and Genetics (Biol. 305). (3). (Excl). (BS).

Credits: (3).

Course Homepage: No Homepage Submitted.

This course is focused on the molecular basis of plant development. Emphasis is placed on the genetic and molecular mechanisms employed by plants to generate regular patterns of cells, tissues, and organs, and to modify those patterns in response to internal and external signals. Following a general introduction to plant molecular biology methods and approaches. The topics will include embryogenesis, meristem function, organ formation, gametogenesis, cell differentiation, plant hormone action, developmental responses to the environment, and signal transduction. These topics will be explored through lecture material and class discussions based on the primary literature. Students will be exposed to the design of experimental approaches and the critical evaluation of research papers. Emphasis is placed on the use of model plant species for the dissection of developmental processes at the molecular and genetic levels. Student evaluation is based on participation in the class discussions and presentations. One midterm and the final exam.

Check Times, Location, and Availability Cost: 1 Waitlist Code: 1

Biol. 412. Teaching Biochemistry by the Keller Plan.

Section Orientation Meeting Thursday, Sept. 9, 1:00pm

Instructor(s): Marcy Osgood (mosgood@umich.edu)

Prerequisites & Distribution: Biol. 311 and permission of instructor. (3). (Excl). This is a graded course. May not be included in any of the Biological Sciences concentration programs. (EXPERIENTIAL).

Credits: (3).

Course Homepage: No Homepage Submitted.

Undergraduates who previously have taken an introductory biochemistry course act as TAs for Introductory Biochemistry (Biology 311). TAs meet with the instructor for a two-hour class each week for lectures, presentations, and discussions of teaching and biochemistry. TAs also prepare a report on a recent advance in biochemistry which they present to their peers and the instructor. The major roles of the TAs are to examine the students on their mastery of unit material and to help the students with explanations supplementary to the textbook. At the completion of an instructor-generated written quiz, the student and TA grade the quiz together. TAs learn considerable biochemistry by repeated teachings of unit materials and, in addition, profit from their experience as teachers and evaluators.

Check Times, Location, and Availability Cost: 1 Waitlist Code: 3: permission of instructor

Biol. 418. Endocrinology.

Anatomy, Physiology, and Development

Section 001.

Instructor(s): Robert Denver (rdenver@umich.edu)

Prerequisites & Distribution: Biol. 162 (or 152-154) or 195; organic chemistry. (3). (Excl). (BS).

Credits: (3).

Course Homepage: No Homepage Submitted.

This course is a comparative study of animal endocrine functions with emphasis on the cellular origin and chemical nature of hormones, the cellular and molecular mechanisms of hormone action, general endocrine control mechanisms, the evolution of hormones and hormonal control and their physiological actions in animals. The course will concentrate on the endocrine systems of vertebrates; there will be limited treatment of human endocrinology. Instruction in Biology 418 assumes a basic familiarity with general and comparative physiology. Training in chemistry through organic is essential, and courses in biochemistry and cell and molecular biology are helpful.

Check Times, Location, and Availability Cost: 2 Waitlist Code: 1

Biol. 422/Anatomy 422. Cellular and Molecular Neurobiology.

Molecular and Cellular Biology

Section 001.

Instructor(s): Rolf Bodmer (rolf@umich.edu) , Bruce Oakley (boakley@umich.edu)

Prerequisites & Distribution: Biol. 162 (or 152-154) or 195, one year of physics, prior or concurrent enrollment in biochemistry. (3). (Excl). (BS).

Credits: (3).

Course Homepage: No Homepage Submitted.

This course deals primarily with the properties of individual nerve cells, and small groups of nerve cells. This provides the basis for understanding information processing by the nervous system, learning and memory, development of neurons, and neurological and psychiatric disorders. Considerable emphasis will be placed on understanding the molecules that endow the nervous system with these properties.

Check Times, Location, and Availability Cost: 1 Waitlist Code: 1

Biol. 423. Introduction to Research in Cellular and Molecular Neurobiology.

Molecular and Cellular Biology

Section This course requires permission of the instructor; contact rhume@umich.edu.

Instructor(s): Richard Hume (rhume@umich.edu)

Prerequisites & Distribution: Concurrent enrollment in Biol. 422; or completion of Biol. 222 or 422, and permission of instructor. (3). (Excl). (BS). Satisfies a Biology laboratory requirement. Laboratory fee ($70) required.

Credits: (3).

Lab Fee: Laboratory fee ($70) required.

Course Homepage: No Homepage Submitted.

This lab course provides an introduction to experimental approaches in neurobiology. Emphasis is on molecular, anatomical, and physiological approaches for studying neuronal function. Among the molecular topics to be covered are analysis of cDNA clones, PCR amplification of DNA and expression of genes in foreign tissues. Among the anatomical topics to be covered are gross and microscopic anatomy of nervous systems, axonal pathway tracing, and immunocytochemical localization of specific neuronal proteins. Among the physiological topics to be covered are intracellular, extracellular and patch clamp recording, as well as the use of computers in the acquisition and analysis of data. This course is intended for students who plan to engage in research in neurobiology.

Check Times, Location, and Availability Cost: 1 Waitlist Code: 3

Biol. 427. Molecular Biology.

Molecular and Cellular Biology

Section 001 Every Student Must Reserve Mondays, Oct. 4, Nov. 8, and Dec. 13, from 6-8pm for Exams

Instructor(s): Robert Helling (helling@umich.edu) , Janine Maddock (maddock@umich.edu)

Prerequisites & Distribution: Biol. 305; and Biol. 310 or 311, or Biol. Chem. 415. (4). (Excl). (BS).

Credits: (4).

Course Homepage: No Homepage Submitted.

Comprehensive coverage of the general principles governing the structures, synthesis, and functions of DNA, RNA, and proteins in the context of the cell. Emphasizes understanding methods and interpretation of data. Topics include genome organization, DNA replication and transposition, chromosome segregation, transcription and translation, the processing of macromolecules, signal transfer, and regulation at various levels. Three lectures per week are supplemented by a 1.5 hour discussion section.

Check Times, Location, and Availability Cost: 3 Waitlist Code: 1

Biol. 428. Cell Biology.

Molecular and Cellular Biology

Section 001 Every Student Must Reserve Mondays, Sept. 27, Oct. 25, and Nov 22, 6-8pm, for Exams

Instructor(s): Jesse Hay (jessejhay@umich.edu) , Laura Olsen (ljo@umich.edu)

Prerequisites & Distribution: Biol. 305; and Biol. 310 or 311, or Biol. Chem. 415. Students with credit for Biol. 320 must obtain permission of instructor. (4). (Excl). (BS).

Credits: (4).

Course Homepage: No Homepage Submitted.

Biology 428 is designed to provide students with a comprehensive overview of the biology of eukaryotes and prokaryotes at the cellular and molecular level. This course is intended for upper-level undergraduates and graduate students. The information is presented at a level that requires students to integrate information from their other biology, chemistry, and biochemistry courses. Topics include: cell structure and function; cell membranes; intracellular organelles and cytoskeleton; inter- and intra-cellular signaling; cell development; and cell cycle. Students will be expected to integrate the scientific data presented in class as well as to read and interpret basic research drawn from the current scientific literature. Grades will be based on four exams and the discussion section.

Check Times, Location, and Availability Cost: 3 Waitlist Code: 1

Biol. 436(336). Introductory Immunology.

Molecular and Cellular Biology

Section 001.

Instructor(s): Eric Mann (ericmann@umich.edu)

Prerequisites & Distribution: Biol. 305 and biochemistry (Biol. 310, 311, or Biol. Chem. 415). (3). (Excl). (BS).

Credits: (3).

Course Homepage: No Homepage Submitted.

This course is intended to introduce pre-professional and biology concentrators to the theoretical and experimental principles of immunology. Topics covered include: a detailed study of the molecules, cells, and organs that constitute the immune system; the innate and adaptive immune responses; and the role of the immune system in host defense, allergy, and organ transplantation. Topics will be illustrated with clinical case studies. Grades are based on six quizzes and two exams. The course is appropriate for concentrations in biology, microbiology, and cell and molecular biology.

Check Times, Location, and Availability Cost: 2 Waitlist Code: 1

Biol. 440/NR&E 422. Biology of Fishes.

Biological Evolution and Diversity

Section 001.

Instructor(s): William Fink (wfink@umich.edu)

Prerequisites & Distribution: Biol. 162 and one additional biology course. (3). (Excl). (BS).

Credits: (3).

Course Homepage: No Homepage Submitted.

Lectures cover many aspects of the biology of lower vertebrates known as fishes, including evolution, physiology, functional morphology, phylogeny, biogeography, ecology, and reproduction. The systematic position of fish among vertebrates is discussed and exemplary assemblages examined. Special attention is given to the effect of the physical properties of water on form, function, and modes of life of fishes. Evaluation of students is based on two take-home exams, a cumulative closed-book final exam, and class participation. All exams emphasize essay questions that will require a synthesis of class material, and logic examination of novel problems. Take-home exams may include numerical problems. An optional laboratory course (Bio 441/NR&E 423) examines field methods, classification, and identification of Michigan fishes.

Check Times, Location, and Availability Cost: 3 Waitlist Code: 4

Biol. 441/NR&E 423. The Biology of Fishes Laboratory.

Biological Evolution and Diversity

Instructor(s): Gerald Smith (grsmith@umich.edu)

Prerequisites & Distribution: Biol. 162 and one additional biology course. (1). (Excl). (BS).

Credits: (1).

Course Homepage: http://www.umich.edu/~bio440/

Optional laboratory course accompanying Biology 440, providing an introduction to the field methods used in fish biology and fisheries, and examining the diversity of the Michigan ichthyofauna and major groups of world fishes.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: No Data Given.

Biol. 451/NR&E 451. Biology of Mammals.

Biological Evolution and Diversity

Section 001.

Instructor(s): Philip Myers (pmyers@umich.edu)

Prerequisites & Distribution: Biol. 162 (or 152-154) or 195. (4). (Excl). (BS). Satisfies a Biology laboratory requirement. Laboratory fee ($75) required.

Credits: (4).

Lab Fee: Laboratory fee ($75) required.

Course Homepage: No Homepage Submitted.

Biology 451 introduces students to the diversity of mammals. Through laboratory exercises (one four-hour laboratory period/week) and lectures, participants will have opportunity to see and learn about species representing all of the major groups of mammals. We will review their evolutionary history; examine adaptations such as those for running, digging, swimming, and flying; and discuss current research in ecology, behavior, zoogeography, and systematics. A text supplements the lectures, and a published manual is required for the laboratory. Grades will be based on lecture and laboratory exams, participation in discussions, and several brief papers.

Check Times, Location, and Availability Cost: 2 Waitlist Code: 1

Biol. 458. Biology of the Algae.

Biological Evolution and Diversity

Section 001.

Instructor(s): Michael Wynne (mwynne@umich.edu)

Prerequisites & Distribution: Biol. 162 (or 152) or 195, or Biol. 255. (5). (Excl). (BS). Satisfies a Biology laboratory requirement. Laboratory fee ($40) required.

Credits: (5).

Lab Fee: Laboratory fee ($40) required.

Course Homepage: No Homepage Submitted.

This course studies the very diverse group of plants and photosynthetic protistans collectively known as "the algae," which includes the prokaryotic blue-green algae (Cyanobacteria) and the eukaryotic green, golden, yellow-green, brown, and red algae as well as well as the euglenoids, dinoflagellates, and cryptomonads. The framework of the course is a systematic orientation, examining representative examples from the various algal groups, mostly from living material but also from prepared slides and preserved specimens. It treats both freshwater and marine types and includes identification, structure, reproduction, ecology, and stresses the interrelationships among the algae. A comparative approach is followed. The use of algae as research tools is stressed, where appropriate. Two lectures and two laboratory sessions per week are scheduled, and two field trips are planned.

Check Times, Location, and Availability Cost: 3 Waitlist Code: 3

Biol. 459. Systematic Botany.

Biological Evolution and Diversity

Section 001.

Instructor(s): Willliam Anderson (wra@umich.edu), Warren Wagner (whwag@umich.edu)

Prerequisites & Distribution: Biol. 162 (or 152-154) or 195, or Biol. 255. (4). (Excl). (BS). Satisfies a Biology laboratory requirement. Laboratory fee ($30) required.

Credits: (4).

Lab Fee: Laboratory fee ($30) required.

Course Homepage: No Homepage Submitted.

Plant biodiversity taught with lectures, color projection slides, specimens, living plants, and laboratories. Emphasis at level of orders, families, and genera, temperate and tropical, to familiarize students with all parts of the world. Focuses mainly on flowering plants but also gymnosperms and pteridophytes. Phylogeny provides the framework: Hypothetical ancestors and different lines are analyzed, e.g., pinks (Caryophyllidae), roses (Rosidae), trees (Hamamelidae), lilies (Liliidae), etc. Subjects like habitats, endangered species, geography, biosystematics, cladistics, floral biology are given special lectures. Plant biosystematics is essential to botanists but the course is needed also by conservationists, ecologists, zoologists, foresters, and ethnobotanists. Some students take the course simply because they enjoy plants. Two midterms, a final, and lab quizzes.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: 1

Biol. 468. Mushrooms and Molds: Biology and Use.

Biological Evolution and Diversity

Section 001.

Instructor(s): Robert Fogel (rfogel@umich.edu)

Prerequisites & Distribution: Biol. 162 (or 154). (5). (Excl). (BS). Satisfies a Biology laboratory requirement. Laboratory fee ($50) required.

Credits: (5).

Lab Fee: Laboratory fee ($50) required.

Course Homepage: No Homepage Submitted.

The mushrooms and molds have changed the course of human history and continue to have a profound impact on man and the global ecosystem as important plant, insect, and human pathogens and as important nutrient recyclers. Their increasing importance in biotechnology has brought new recognition to these fascinating and unique organisms. This course surveys the members of the Kingdom Fungi, provides an introduction to their ecology, physiology, genetics, and importance in biotechnology, medical mycology, and plant pathology through lectures, laboratories, and field trips. This course is important for students interested in careers in biotechnology, medical mycology, biodiversity, plant pathology, forest pathology, systematics, and ecology. Grades are based on three hourly exams and a term project on a topic of the students' choice. General Biology (Biol 162), or equivalent, is a recommended prerequisite.

Check Times, Location, and Availability Cost: 2 Waitlist Code: 3

Biol. 477. Laboratory in Field Ecology.

Ecology and Population Biology

Section 001 This course will meet September 17 October 29, beginning at 7:00pm Friday evenings and concluding Sunday evenings at 7:00pm

Instructor(s): Lisa Curran (lcurran@umich.edu) , John Vandermeer (jvander@umich.edu), Ivette Perfecto (perfecto@umich.edu)

Prerequisites & Distribution: A course in ecology. (5). (Excl). (BS). Laboratory fee ($30) required.

Credits: (5).

Lab Fee: Laboratory fee ($30) required.

Course Homepage: No Homepage Submitted.

Organizational meeting, 5pm in 2044 Nat. Sci. on Wednesday, September 8. This course will meet September 17 October 29, beginning at 7:00pm Friday evenings and concluding Sunday evenings at 7:00pm. There will also be a weekly meeting on Tuesdays from 5-7pm.

Ecology students require intensive practice in making field observations and systematically exploring the implications of those observations. One vehicle for doing so is the "field problem" based course, in which a faculty member chooses a general topic and works with a small group of students exploring that topic for an entire day. The field problem-based course is distinct from the laboratory course in that field problems seek to explore an unknown area. The course does not include "set labs" or repeats of well-known patterns. The professor and students seek to explore a specific research question that has not been examined before. The exercise of working through the details of a new problem along with the professor gives the student practice in the creative part of the scientific endeavor. Working with a variety of faculty members the student experiences several "styles" of doing science. The general structure of the course, centered around the field problem, encourages a great deal of discussion among students and between students and faculty. A major goal of the course is to facilitate that discussion. In addition, there is a relatively large lecture load, with an average of four lectures per week.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: 1

Biol. 480. Computer-Aided Inferences in Evolution and Ecology.

Ecology and Population Biology

Section 001.

Instructor(s): George Estabrook (gfred@umich.edu)

Prerequisites & Distribution: Senior natural science concentrator or graduate student. (4). (Excl). (BS).

Credits: (4).

Course Homepage: No Homepage Submitted.

This course is for prospective professional researchers in natural science who want to learn the concepts, techniques, and language skills to formulate hypotheses so that computers (rather than mathematics) can derive predictions with which to compare data. Such hypotheses are less constrained by mathematical needs and so can better meet the needs of natural science. The course will provide instruction (or review) in the fundamentals of PASCAL programming, and most techniques will be provided as PASCAL PROCEDURES already written and ready for you to use. No prior programming experience is required, and a working knowledge of high school algebra is sufficient. The course provides instruction (or review) of probability processes that can (and must) be made part of your scientific hypothesis. Predictions take the form of probability distributions that can directly impute significance to your observed data. Students work with the data of their choice, and discuss applications of the concepts in their areas of interest. A term project replaces the final exam. Lectures, discussion, computer lab.

Check Times, Location, and Availability Cost: 1 Waitlist Code: No Data Given.

Biol. 481. Population Dynamics and Ecology.

Ecology and Population Biology

Section 001.

Instructor(s): John Vandermeer (jvander@umich.edu) , Mark Wilson (wilsonml@umich.edu)

Prerequisites & Distribution: A course in ecology. Calculus is strongly recommended. (4). (Excl). (BS).

Credits: (4).

Course Homepage: No Homepage Submitted.

An examination of the principles of population ecology. Theoretical and empirical research on population dynamics and regulation of managed and natural populations are emphasized, as well as the development of the mathematical and computer skills for modeling dynamics of single and interacting populations. Specific topics include concepts of linear and nonlinear dynamics, demography, life history evolution, density-dependence and population regulation, and basic models of competition, mutualism, predator-prey, host-disease, and other population interactions. A background in ecology or permission of the instructor is required. There will be two 1.5 hour lectures and one 2 hour discussion section a week. Discussion sections will cover original readings from the literature and techniques for modeling populations. Course requirements include computer modeling projects and writeups, a midterm, and a final.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: 1

Biol. 489/NR&E 430. Soil Properties and Processes.

Ecology and Population Biology

Section 001.

Instructor(s): Donald Zak (drzak@umich.edu)

Prerequisites & Distribution: Biol. 162 and chemistry. (3). (Excl). (BS). Satisfies a Biology laboratory requirement. Laboratory fee ($25) required.

Credits: (3).

Lab Fee: Laboratory fee ($25) required.

Course Homepage: No Homepage Submitted.

Soil as a central component of terrestrial ecosystems, with a particular emphasis on physical, chemical, microbiological processes as they are related to plant growth. Quantitative analysis and interpretation of field and laboratory data are stressed throughout the course. Temperate forest ecosystems are the primary focus of the course; however, numerous examples are drawn from boreal, temperate, and tropical ecosystems. Knowledge of plant ecology is beneficial and prerequisites include introductory biology and chemistry.

Check Times, Location, and Availability Cost: 4 Waitlist Code: 2

Biol. 498. The Ecology of Agroecosystems.

Ecology and Population Biology

Section 001.

Instructor(s): John Vandermeer (jvander@umich.edu)

Prerequisites & Distribution: A course in ecology. (3). (Excl). (BS).

Credits: (3).

Course Homepage: No Homepage Submitted.

An analysis of ecological principles as they apply to agricultural ecosystems, emphasizing theoretical aspects but also covering empirical results of critical experiments. While the emphasis is on principles, practical applicability is also explored where appropriate. Physical, biological, and social forces will be integrated as necessary. Designed as preparation for active research in agroecosytem ecology.

Check Times, Location, and Availability Cost: 4 Waitlist Code: 3

Biol. 514. Topics in Molecular Evolution.

Biological Evolution and Diversity

Section 001 Comparative DNA/Amino Acid Sequence Analysis

Instructor(s): Priscilla Tucker (ptuck@umich.edu)

Prerequisites & Distribution: Biol. 305 and one upper-level course in either molecular or evolutionary biology, and permission of instructor. (3). (Excl). (BS).

Credits: (3).

Course Homepage: No Homepage Submitted.

The subject of this course is methods of comparative DNA/amino acid sequence analysis using an evolutionary approach. Topics of sequence alignment and phylogeny reconstruction using DNA and protein sequences are covered.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: No Data Given.

Biol. 521. Bacterial Physiology II: Carbon Metabolism.

Section 001 Meets Oct. 12 Nov. 4

Instructor(s): Robert Bender (rbender@umich.edu)

Prerequisites & Distribution: Biol. 305, and Biol. 310 or 311 or Biol. Chem. 415. (1). (Excl). (BS).

Mini/Short course

Credits: (1).

Course Homepage: No Homepage Submitted.

This course will focus on central metabolism especially the catabolism of glucose, lactose, and amino acids. Among the topics considered will be: (1) "The memory paradox" where bacterial cells remember how they were grown 40 generations ago in the absence of external reminder; (2) the integration of pathways and how changes in one effect the flow of another; and (3) global regulators (known and unknown) that integrate complex signals and transmit them into gene expression responses. Biochemistry shows that pathways exist, physiology asks the questions of how they function and why they are important. The key theme of the course will be regulation rather than memorizing pathways. Bacterial Physiology II is entirely independent of the related Bacterial Physiology I and III courses and can be taken without either of the others.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: No Data Given.

Biol. 522. Bacterial Physiology III: Nitrogen Metabolism.

Section 001 Meets Nov. 9 Dec. 9

Instructor(s): Robert Bender (rbender@umich.edu)

Prerequisites & Distribution: Biol. 305, and Biol 310, 311, or Biol. Chem 415. (1). (Excl). (BS).

Mini/Short course

Credits: (1).

Course Homepage: No Homepage Submitted.

This course will focus on the interconversion of various kinds of nitrogen sources. Topics will include the reduction of nitrate and atmospheric nitrogen to ammonia and the catabolism of urea and amino acids. Emphasis will be on the regulation of these pathways and the regulatory features that allow cells to use only the "appropriate" nitrogen sources to supply their needs. For example, how does a cell know to use the urea before porline as a nitrogen source (and ammonia before urea)? The key theme of the course will be regulation and the logical methods used to figure out how regulation functions. Bacterial Physiology III is entirely independent of the related Bacterial Physiology I and II courses and can be taken without either of the others. The course is intended for graduate students and upper class undergraduates with an interest in microbiology or biochemical regulation.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: No Data Given.

Biol. 525/Chem. 525. Chemical Biology I.

Section 100.

Instructor(s): Neil Marsh (nmarsh@umich.edu), Glick

Prerequisites & Distribution: Chemistry 451, 452, 461, and 463. (3). (Excl). (BS).

Credits: (3).

Course Homepage: No Homepage Submitted.

See Chemistry 525.100.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: No Data Given.

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