College of LS&A

Fall Academic Term '02 Graduate Course Guide

Note: You must establish a session for Fall Academic Term 2002 on wolverineaccess.umich.edu in order to use the link "Check Times, Location, and Availability". Once your session is established, the links will function.

Courses in Molecular, Cellular, and Developmental Biology


This page was created at 7:30 PM on Thu, Oct 3, 2002.

Fall Academic Term, 2002 (September 3 - December 20)


MCDB 400(BIOLOGY 400). Advanced Research.

Instructor(s):

Prerequisites: 12 credits of biology, 3.0 average in science, and permission of faculty member in biology. (1-3). (INDEPENDENT). May be repeated for a total of 9 credits.

Credits: (1-3).

Course Homepage: No homepage submitted.

Intended for those engaged in original research at an advanced level. This course number is most frequently elected by senior Honors students who have completed MCDB 300 and who are completing their research and writing their thesis. A final paper is required. (Refer to the description of MCDB 300 for more information.)

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: 5, Permission of Department

MCDB 411(BIOLOGY 411). Protein Structure and Function.

Section 001.

Instructor(s): James Bardwell (jbardwel@umich.edu)

Prerequisites: BIOLOGY 310, 311, or BIOLCHEM 415. (3).

Credits: (3).

Course Homepage: http://www.biology.lsa.umich.edu/courses/bio411/

A taste of bioinformatics. This course is a practical hands-on approach to extract information about protein and DNA sequences. Students will learn how to do elementary sequence analysis databases, searching, alignment, and 3D-structure prediction using analysis tools that are available on the web. Students will learn how to get the most out of their sequence. We will also discuss how protein structure is related to function, and investigate how proteins fold.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: No Data Given.

MCDB 412(BIOLOGY 412). Teaching Biochemistry by the Keller Plan.

Section 001.

Instructor(s): Kenneth J Balazovich

Prerequisites: BIOLOGY 311 and permission of instructor. (3). May not be included in any of the Biological Sciences concentration programs. (EXPERIENTIAL).

Credits: (3).

Course Homepage: No homepage submitted.

Undergraduates who previously have taken an introductory biochemistry course act as TAs for Introductory Biochemistry (Biology 311). TAs meet with the instructor for a two-hour class each week for lectures, presentations, and discussions of teaching and biochemistry. TAs also prepare a report on a recent advance in biochemistry which they present to their peers and the instructor. The major roles of the TAs are to examine the students on their mastery of unit material and to help the students with explanations supplementary to the textbook. At the completion of an instructor-generated written quiz, the student and TA grade the quiz together. TAs learn considerable biochemistry by repeated teachings of unit materials and, in addition, profit from their experience as teachers and evaluators.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: 5, Permission of Instructor

MCDB 418(BIOLOGY 418). Endocrinology.

Section 001.

Instructor(s): Robert J Denver (rdenver@umich.edu)

Prerequisites: BIOLOGY 162, 225, and organic chemistry. (3).

Credits: (3).

Course Homepage: http://www.biology.lsa.umich.edu/courses/bio418/bio418.htm

This course is a comparative study of animal endocrine functions with emphasis on the cellular origin and chemical nature of hormones, the cellular and molecular mechanisms of hormone action, general endocrine control mechanisms, the evolution of hormones and hormonal control and their physiological actions in animals. The course will concentrate on the endocrine systems of vertebrates; there will be limited treatment of human endocrinology. Instruction in BIOLOGY 418 assumes a basic familiarity with general and comparative physiology. Training in chemistry through organic is essential, and courses in biochemistry and cell and molecular biology are helpful.

Textbook: Vertebrate Endocrinology. 3rd. edition. D.O. Norris.

Check Times, Location, and Availability Cost: 2 Waitlist Code: 1

MCDB 419(BIOLOGY 419). Endocrinology Laboratory.

Section 001.

Instructor(s): Sushama Denver (spavgi@umich.edu)

Prerequisites: Prior or concurrent enrollment in BIOLOGY 225 or 310 or 311, or MCDB 418 or 426. (3). Satisfies a Biology laboratory requirement. Laboratory fee ($70) required.

Credits: (3).

Lab Fee: Laboratory fee ($70) required.

Course Homepage: No homepage submitted.

This laboratory course provides hands-on experience with methods used in endocrinological investigations. The students will learn techniques ranging from the organismal to the molecular level. The course emphasizes hypothesis testing, modern techniques, and data analysis. Prior or concurrent enrollment in BIOLOGY 418 is required to take this course. The enrollment is limited to 12 students. Students should be aware that this course uses live animals. The laboratory will meet twice a week (a four-hour session and a two-hour session), however, students should anticipate an additional two or three hours laboratory time at various (and occasionally odd) times in the week. Course assignments include a term paper, quizzes, and other short assignments.

Check Times, Location, and Availability Cost: 1 Waitlist Code: 1

MCDB 422(BIOLOGY 422) / ANAT 422. Cellular and Molecular Neurobiology.

Section 001.

Instructor(s): John Y Kuwada (kuwada@umich.edu), Bruce Oakley (boakley@umich.edu)

Prerequisites: BIOLOGY 162, one year of physics, prior or concurrent enrollment in biochemistry. (3).

Credits: (3).

Course Homepage: No homepage submitted.

This course deals primarily with the properties of individual nerve cells, and small groups of nerve cells. This provides the basis for understanding information processing by the nervous system, learning and memory, development of neurons, and neurological and psychiatric disorders. Considerable emphasis will be placed on understanding the molecules that endow the nervous system with these properties.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: 1

MCDB 423(BIOLOGY 423). Introduction to Research in Cellular and Molecular Neurobiology.

Section 001.

Instructor(s): Richard I Hume (rhume@umich.edu)

Prerequisites: Concurrent enrollment in MCDB 422; or completion of BIOLOGY 222 or MCDB 422, and permission of instructor. (3). Satisfies a Biology laboratory requirement. Laboratory fee ($70) required.

Credits: (3).

Lab Fee: Laboratory fee ($70) required.

Course Homepage: http://www.biology.lsa.umich.edu/~www/bio423/bio423syl.htm

This lab course provides an introduction to experimental approaches in neurobiology. Emphasis is on molecular, anatomical, and physiological approaches for studying neuronal function. Among the molecular topics to be covered are analysis of cDNA clones, PCR amplification of DNA, and expression of genes in foreign tissues. Among the anatomical topics to be covered are gross and microscopic anatomy of nervous systems, axonal pathway tracing, and immunocytochemical localization of specific neuronal proteins. Among the physiological topics to be covered are intracellular and extracellular recording, as well as the use of computers in the acquisition and analysis of data. This course is intended for students who plan to engage in research in neurobiology. A course pack is required.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: 5, Permission of Instructor

MCDB 427(BIOLOGY 427). Molecular Biology.

Section 001.

Instructor(s): Rolf Andre Bodmer (rolf@umich.edu), Jianming Li (jian@umich.edu)

Prerequisites: BIOLOGY 305; and BIOLOGY 310 or 311, or BIOLCHEM 415. (4).

Credits: (4).

Course Homepage: http://www.biology.lsa.umich.edu/courses/MCDB427/

Comprehensive coverage of the general principles governing the structures, synthesis, and functions of DNA, RNA, and proteins in the context of the cell. Emphasizes understanding methods and interpretation of data. Topics include genome organization, DNA replication and transposition, chromosome segregation, transcription and translation, the processing of macromolecules, signal transfer, and regulation at various levels. Two lectures per week are supplemented by a 1.5 hour discusssion section.

Check Times, Location, and Availability Cost: 3 Waitlist Code: 1

MCDB 521(BIOLOGY 521). Bacterial Physiology II: Carbon Metabolism.

Section 001 THIS COURSE WILL MEET OCT. 8 - NOV. 5. (Drop/Add deadline=October 14).

Instructor(s): Robert A Bender (rbender@umich.edu)

Prerequisites: BIOLOGY 305, and BIOLOGY 310 or 311 or BIOLCHEM 415. (1).

Mini/Short course

Credits: (1).

Course Homepage: http://www.biology.lsa.umich.edu/courses/bio521/home.htm.

This course will focus on central metabolism especially the catabolism of glucose, lactose, and amino acids. Among the topics considered will be: (1) "The memory paradox" where bacterial cells remember how they were grown 40 generations ago in the absence of external reminder; (2) the integration of pathways and how changes in one effect the flow of another; and (3) global regulators (known and unknown) that integrate complex signals and transmit them into gene expression responses. Biochemistry shows that pathways exist, physiology asks the questions of how they function and why they are important. The key theme of the course will be regulation rather than memorizing pathways.

Bacterial Physiology II is entirely independent of the related Bacterial Physiology I and III courses and can be taken without either of the others.

Check Times, Location, and Availability Cost: 1 Waitlist Code: No Data Given.

MCDB 522(BIOLOGY 522). Bacterial Physiology III: Nitrogen Metabolism.

Section 001 THIS COURSE WILL MEET NOV. 7 - DEC. 10. (Drop/Add deadline=November 13).

Instructor(s): Robert A Bender (rbender@umich.edu)

Prerequisites: BIOLOGY 305, and BIOLOGY 310, 311, or BIOLCHEM 415. (1).

Mini/Short course

Credits: (1).

Course Homepage: http://www.biology.lsa.umich.edu/courses/bio522/home.htm

This course will focus on the interconversion of various kinds of nitrogen sources. Topics will include the reduction of nitrate and atmospheric nitrogen to ammonia and the catabolism of urea and amino acids. Emphasis will be on the regulation of these pathways and the regulatory features that allow cells to use only the "appropriate" nitrogen sources to supply their needs. For example, how does a cell know to use the urea before porline as a nitrogen source (and ammonia before urea)? The key theme of the course will be regulation and the logical methods used to figure out how regulation functions.

Bacterial Physiology III is entirely independent of the related Bacterial Physiology I and II courses and can be taken without either of the others. The course is intended for graduate students and upper class undergraduates with an interest in microbiology or biochemical regulation.

Check Times, Location, and Availability Cost: 1 Waitlist Code: No Data Given.

MCDB 525(BIOLOGY 525) / CHEM 525. Chemical Biology I.

Section 100.

Instructor(s): Richard A Goldstein

Prerequisites: CHEM 451, 452, 461, and 463. (3).

Credits: (3).

Course Homepage: http://coursetools.ummu.umich.edu/2002/fall/chem/525/001.nsf

See Chemistry 525.001.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: No Data Given.

MCDB 608(BIOLOGY 608) / BIOPHYS 608 / PHYSICS 608. Biophysical Principles of Microscopy.

Section 001.

Instructor(s): Daniel Axelrod (daxelrod@umich.edu)

Prerequisites: Knowledge of complex exponential notation, and graduate standing. (3).

Credits: (3).

Course Homepage: No homepage submitted.

See Biophysics 608.001.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: No Data Given.

MCDB 610 / NEUROSCI 601. Principles Neuroscience I.

Instructor(s):

Prerequisites: Enrollment in a Ph.D. program. Graduate students in Master's degree programs may register only with the permission of the instructor. (4).

Credits: (4).

Course Homepage: http://www.biology.lsa.umich.edu/courses/neu601/neu601.htm

Neuroscience 601 represents the first half of a year long, graduate-level survey of neuroscience. The goals for Neuroscience 601 and 602 are: 1) To provide our students with a sense of the state of current knowledge in molecular, cellular, developmental, integrative and cognitive neuroscience. Considerable emphasis is put on pulling together information obtained from different types of investigations (anatomical, physiological, behavioral, biochemical, genetic) to gain a balanced view of neuroscience. 2) To provide our students with a sense of how knowledge was obtained, by reading and discussing "classic papers." 3) To provide our students with a sense of where the current frontier is, by reading and discussing very recent papers. Each week this class meets for 3-5 hours, with a mix of lectures and discussion. The major topics treated in Neuroscience 601 and 602 are: I) Excitable Membranes, II) Molecular Neuropharmacology, and III) Developmental Neurobiology. This is a Fall Term course. (4 credits)

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: No Data Given.

MCDB 611 / NEUROSCI 611. Excitable Membranes.

Excitable Membranes MEETS SEPT 3 - 26. (Drop/Add deadline=September 23).

Instructor(s): Gisela F Wilson (wilsongf@umich.edu), Edward L Stuenkel

Prerequisites: Enrollment in a Ph.D. program. Graduate students in Master's degree programs may register only with the permission of the instructor. (1).

Mini/Short course

Credits: (1).

Course Homepage: http://www.biology.lsa.umich.edu/courses/neu601/neu601.htm

Represents the first half of a year long, graduate-level survey of neuroscience. The goals for Neuroscience 601 and 602 are: 1) To provide our students with a sense of the state of current knowledge in molecular, cellular, developmental, integrative and cognitive neuroscience. Considerable emphasis is put on pulling together information obtained from different types of investigations (anatomical, physiological, behavioral, biochemical, genetic) to gain a balanced view of neuroscience. 2) To provide our students with a sense of how knowledge was obtained, by reading and discussing "classic papers." 3) To provide our students with a sense of where the current frontier is, by reading and discussing very recent papers. Each week this class meets for 3-5 hours, with a mix of lectures and discussion. The major topics treated in Neuroscience 601 and 602 are: I) Excitable Membranes, II) Molecular Neuropharmacology, and III) Developmental Neurobiology. Students who wish to study only a single area of neuroscience may register for single modules of the course (Module 1, Excitable membranes = Neuroscience 611; Module 2, Molecular Neuropharmacology = Neuroscience 612 or Pharmcology 615; Module 3, Development of the Nervous System= Neuroscience 613) for one credit each. Students who complete Neuroscience 601 will receive 4 credits.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: No Data Given.

MCDB 613 / NEUROSCI 613. Central Nervous System Physiology and Development.

Nov. 12-Dec 10 (Drop/Add deadline=November 15).

Instructor(s): John Y Kuwada (kuwada@umich.edu)

Prerequisites: Enrollment in a Ph.D. program. Graduate students in Master's degree programs may register only with the permission of the instructor. (1).

Mini/Short course

Credits: (1).

Course Homepage: http://www.biology.lsa.umich.edu/courses/neu601/neu601.htm

Represents the first half of a year long, graduate-level survey of neuroscience. The goals for Neuroscience 601 and 602 are: 1) To provide our students with a sense of the state of current knowledge in molecular, cellular, developmental, integrative and cognitive neuroscience. Considerable emphasis is put on pulling together information obtained from different types of investigations (anatomical, physiological, behavioral, biochemical, genetic) to gain a balanced view of neuroscience. 2) To provide our students with a sense of how knowledge was obtained, by reading and discussing "classic papers." 3) To provide our students with a sense of where the current frontier is, by reading and discussing very recent papers. Each week this class meets for 3-5 hours, with a mix of lectures and discussion. The major topics treated in Neuroscience 601 and 602 are: I) Excitable Membranes, II) Molecular Neuropharmacology, and III) Developmental Neurobiology. Students who wish to study only a single area of neuroscience may register for single modules of the course (Module 1, Excitable membranes = Neuroscience 611; Module 2, Molecular Neuropharmacology = Neuroscience 612 or Pharmcology 615; Module 3, Development of the Nervous System= Neuroscience 613) for one credit each. Students who complete Neuroscience 601 will receive 4 credits.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: No Data Given.

MCDB 630(BIOLOGY 630) / MICRBIOL 630 / CMBIOL 630 / HUMGEN 630 / PHRMACOL 630. Genetics Short Course.

Retroviral Evolution and Pathogenesis. Oct. 17, 31, Nov. 6, 8, 12., 3:00 p.m. - 5:00 p.m. (Drop/Add deadline=October 30).

Instructor(s): Miriam H Meisler (meislerm@umich.edu)

Prerequisites: Graduate standing. (1). May be repeated for credit.

Mini/Short course

Credits: (1).

Course Homepage: No homepage submitted.

No Description Provided. Contact the Department.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: No Data Given.

MCDB 632 / HUMGEN 632. Experimental Genetics Systems.

Section 001.

Instructor(s): Miriam H Meisler (meislerm@umich.edu)

Prerequisites: (1). May be repeated for a total of three credits.

Credits: (1).

Course Homepage: No homepage submitted.

No Description Provided. Contact the Department.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: No Data Given.

MCDB 680(BIOLOGY 680) / CMBIOL 680 / HUMGEN 680 / NEUROSCI 680 / PATH 680 / PHYSIOL 680 / CDB 680. Organogenesis of a Complex Tissue Module I: Neural Crest.

Section 001 Sept. 3-26, 2002 (Drop/Add deadline=September 23).

Instructor(s): Deborah L Gumucio

Prerequisites: Graduate Cell biology recommended, but not required. Graduate standing. (1).

Mini/Short course

Credits: (1).

Course Homepage: http://www.med.umich.edu/medschool/organo/courses.htm

See Physiology 680.001.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: No Data Given.

MCDB 682(BIOLOGY 682) / CMBIOL 681 / HUMGEN 681 / NEUROSCI 681 / PATH 681 / PHYSIOL 681 / CDB 681. Organogenesis of a Complex Tissue Module II: Skeletal Muscle.

Section 001 Oct. 3-29, 2002 (Drop/Add deadline=October 9).

Instructor(s): Deborah L Gumucio

Prerequisites: Graduate Cell biology recommended, but not required. Graduate standing. (1).

Mini/Short course

Credits: (1).

Course Homepage: http://www.med.umich.edu/medschool/organo/courses.htm

See Physiology 681.001.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: No Data Given.

MCDB 683(BIOLOGY 683) / CMBIOL 682 / HUMGEN 682 / NEUROSCI 682 / PATH 682 / PHYSIOL 682. Organogenesis of a Complex Tissue Module III: Gut.

Section 001 Nov. 5 - Dec. 3, 2002 (Drop/Add deadline=November 11).

Instructor(s): Deborah L Gumucio

Prerequisites: Graduate Cell Biology recommended, but not required. Graduate standing. (1).

Mini/Short course

Credits: (1).

Course Homepage: http://www.med.umich.edu/medschool/organo/courses.htm

See Physiology 682.001.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: No Data Given.

MCDB 700. Advanced Studies.

Instructor(s):

Prerequisites: Sixteen hour of biology and permission of instructor. (1-8).

Credits: (1-8).

Course Homepage: No homepage submitted.

No Description Provided. Contact the Department.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: No Data Given.

MCDB 800(BIOLOGY 801). Biology Seminars.

Section 001 DEPARTMENTAL SEMINAR.

Instructor(s):

Prerequisites: Graduate standing and permission of instructor. (1). May be repeated for credit.

Credits: (1).

Course Homepage: No homepage submitted.

No Description Provided. Contact the Department.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: No Data Given.

MCDB 800(BIOLOGY 801). Biology Seminars.

Section 002 ION CHANNELS.

Instructor(s): Gisela F Wilson (wilsongf@umich.edu)

Prerequisites: Graduate standing and permission of instructor. (1). May be repeated for credit.

Credits: (1).

Course Homepage: No homepage submitted.

No Description Provided. Contact the Department.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: No Data Given.

MCDB 800(BIOLOGY 801). Biology Seminars.

Section 003 TOPICS IN CELLULAR AND MOLECULAR NEUROBIOLOGY.

Instructor(s): Rolf Andre Bodmer (rolf@umich.edu)

Prerequisites: Graduate standing and permission of instructor. (1). May be repeated for credit.

Credits: (1).

Course Homepage: No homepage submitted.

No Description Provided. Contact the Department.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: No Data Given.

MCDB 800(BIOLOGY 801). Biology Seminars.

Section 004 PLANT CELL AND MOLECULAR BIOLOGY SEMINAR.

Instructor(s): Laura J Olsen (ljo@umich.edu)

Prerequisites: Graduate standing and permission of instructor. (1). May be repeated for credit.

Credits: (1).

Course Homepage: No homepage submitted.

No Description Provided. Contact the Department.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: No Data Given.

MCDB 800(BIOLOGY 801). Biology Seminars.

Section 005 MCDB PROSEMINAR.

Instructor(s): John Y Kuwada (kuwada@umich.edu)

Prerequisites: Graduate standing and permission of instructor. (1). May be repeated for credit.

Credits: (1).

Course Homepage: No homepage submitted.

No Description Provided. Contact the Department.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: No Data Given.

MCDB 801(BIOLOGY 801). Supervised Teaching.

Instructor(s):

Prerequisites: Graduate standing and permission of instructor. Appointment as Teaching Assistant in Biology. (2; 1 credit for GSI Training course). (INDEPENDENT).

Credits: (2; 1 credit for GSI Training course).

Course Homepage: No homepage submitted.

No Description Provided. Contact the Department.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: No Data Given.

MCDB 990(BIOLOGY 990). Dissertation/Precandidate.

Instructor(s):

Prerequisites: Election for dissertation work by doctoral student not yet admitted as a Candidate. Graduate Standing. (1-8). (INDEPENDENT). May be repeated for credit.

Credits: (1-8; 1-4 in the half-term).

Course Homepage: No homepage submitted.

Election for dissertation work by doctoral student not yet admitted as a Candidate.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: 5, Permission of Department

MCDB 995(BIOLOGY 995). Dissertation/Candidate.

Instructor(s):

Prerequisites: Graduate School authorization for admission as a doctoral Candidate. Graduate Standing. (8). (INDEPENDENT). May be repeated for credit.

Credits: (8; 4 in the half-term).

Course Homepage: No homepage submitted.

Graduate School authorization for admission as a doctoral Candidate. N.B. The defense of the dissertation (the final oral examination) must be held under a full term Candidacy enrollment period.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: 5, Permission of Department

Undergraduate Course Listings for MCDB.


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This page was created at 7:30 PM on Thu, Oct 3, 2002.


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