College of LS&A

Winter '01 Graduate Course Guide

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Courses in Chemistry


This page was created at 9:03 PM on Mon, Jan 29, 2001.

Winter Term, 2001 (January 4 April 26)

Open courses in Chemistry
(*Not real-time Information. Review the "Data current as of: " statement at the bottom of hyperlinked page)

Wolverine Access Subject listing for CHEM

Winter Term '01 Time Schedule for Chemistry.


CHEM 420. Intermediate Organic Chemistry.

Section 100 EXAMS TUESDAYS, FEB. 6, MAR. 13, AND APR. 10, 6:00-8:00 P.M. REVIEW SESSIONS ON MONDAYS, 7:00-9:00 P.M. IN ROOM 1640 CHEM.

Instructor(s): William Pearson (wpearson@umich.edu)

Prerequisites: Chem. 215/216. (3).

Credits: (3).

Course Homepage: No Homepage Submitted.

Chemistry 420 is an exploration of selected topics in organic chemistry. The course builds on the basic concepts of structure and reactivity considered in Chemistry 210 and 215. Emphasis will be on the mechanisms of organic reactions. Molecular rearrangements and reactions involving the major types of intermediates carbocations, carboanions, free radicals, and carbenes will be covered in detail. The course is intended to strengthen the student's understanding of modern organic chemistry. It may serve as a terminal course on the topic or as a bridge between the first year of organic chemistry and further study in the area. Grading in the course will be based on three hour examinations and a final exam or a term paper (to be determined).

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CHEM 447. Physical Methods of Analysis.

Section 100 EXAMS TUESDAYS, JAN. 30, MAR. 6, AND APR. 3, 6:00-8:00 P.M.

Instructor(s): Mark Meyerhoff (mmeyerho@umich.edu)

Prerequisites: Chem. 260 and 241/242. (3).

Credits: (3).

Course Homepage: http://www.umich.edu/~chem447/

This course introduces the student to the principles and techniques of modern analytical chemistry. Atomic and molecular spectroscopy, mass spectrometry, chromatographic separation techniques, and contemporary electroanalytical chemistry are stressed. The principles of data collection and the processing and representation of analytical signals are introduced.

Exams: 4 (each worth 25% of grade) Schedule for first 3 exams (6-8 pm): January 30, March 6, April 3 The 4 th exam, given during final exam week, will cover material from April 4 to remainder of term plus ACS exam type multiple choice questions covering topics from entire course!

Required Textbook: D. A. Skoog, F. J. Holler and T. A. Nieman, "Principles of Instrumental Analysis," 5th Edition, Saunders, 1997.

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CHEM 452/Biol. Chem. 452. Introduction to Biochemistry II.

Section 100 EXAMS MONDAYS, FEB. 5 AND MAR. 12, 6:00-8:00 P.M.

Instructor(s): Alex Ninfa (aninfa@umich.edu), James Peliska (peliska@umich.edu)

Prerequisites: Chem. 451. (4).

Credits: (4).

Course Homepage: No Homepage Submitted.

This course is the second in a two-term sequence designed for students who are concentrators in biochemistry. Emphasis is on developing the capacity of the students to think about complex biological processes in terms of the underlying chemistry. Initially nucleic acids and nucleotides are discussed. The biosynthesis of amino acids and their utilization in cellular metabolism, including protein synthesis, serves as a primer for an introduction to biochemical genetics and virology.

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CHEM 461. Physical Chemistry I.

Section 100 EXAMS ON TUESDAYS, FEB 13 AND MAR 20,6:00-8:00 P.M.

Instructor(s): Henry Griffin (hcg@umich.edu)

Prerequisites: Chem. 260, Phys. 240, and Math. 215. (3).

Credits: (3).

Course Homepage: No Homepage Submitted.

This is the second of the three-term physical chemistry sequence Chemistry 260/461/463. Chemistry 461 builds on the introduction to quantum mechanics that was given in Chemistry 260. Students will use the Schrödinger Equation in 1-, 2-, and 3-dimensions to solve exactly a series of important chemical problems including the harmonic oscillator, the rigid rotor, and the hydrogen atom. Group theory is introduced as an aid for understanding spectroscopic selection rules. Advanced spectroscopy, including transition probabilities, normal vibrational modes, and photoelectron spectroscopies are introduced and then used to deduce molecular structure. The valence-bond and molecular orbital theories of chemical bonding are discussed, and methods for performing quantum chemical calculations, including variational and perturbation methods, are introduced. The quantum mechanics of spin and angular momentum are discussed and used to interpret magnetic resonance spectra.

NOTE: Students are strongly encouraged to elect the Computational Chemistry Laboratory (Chemistry 462, 1 credit) in the same term that Chemistry 461 is taken.

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CHEM 462. Computational Chemistry Laboratory.

Instructor(s): Henry Griffin (hcg@umich.edu)

Prerequisites: Math. 215, and prior or concurrent enrollment in Chem. 461. (1).

Credits: (1).

Course Homepage: No Homepage Submitted.

This course introduces modern computational tools for symbolic mathematics and for graphical display (Mathematica and Maple). Examples are given of the use of these tools for solving problems in quantum mechanics and quantum chemistry, including exploration of the functional forms of wave functions, solutions of simple differential equations, and diagonalization of Hamiltonians. Molecular modeling software (HyperChem and CAChe) is introduced and used to perform both ab initio and semi-empirical quantum chemical calculations. The examples used are taken largely from the topics discussed in Chemistry 461.

NOTE: Students are strongly encouraged to elect the second term of Physical Chemistry (Chemistry 461, 3 credits) in the same term that Chemistry 462 is taken.

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CHEM 463. Physical Chemistry II.

Section 100 EXAMS ON TUESDAYS, FEB 13 AND MAR 20, 6:00-8:00 P.M.

Instructor(s): John Gland (gland@umich.edu)

Prerequisites: Chem. 461/462. (3).

Credits: (3).

Course Homepage: No Homepage Submitted.

This is the third of the three-term physical chemistry sequence Chemistry 260/461/463 and builds on material presented in both previous courses. The rigorous mathematical theory of classical thermodynamics will be developed, including applications to entropy, heat engines, solution properties, and phase and chemical equilibria. Modern statistical thermodynamics will be introduced. Modern theories of fundamental reaction rates will be used built on the phenomenological kinetics introduced in Chemistry 260. Methods for determining and understanding solid state structures will be discussed, building on group theory introduced in Chemistry 461.

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CHEM 463. Physical Chemistry II.

Section 200 (Honors). EXAMS ON TUESDAYS, FEB 13 AND MAR 20, 6:00-8:00 P.M.

Instructor(s): David Lubman (dmlubman@umich.edu)

Prerequisites: Chem. 461/462. (3).

Credits: (3).

Course Homepage: No Homepage Submitted.

This is the third of the three-term physical chemistry sequence Chemistry 260/461/463 and builds on material presented in both previous courses. The rigorous mathematical theory of classical thermodynamics will be developed, including applications to entropy, heat engines, solution properties, and phase and chemical equilibria. Modern statistical thermodynamics will be introduced. Modern theories of fundamental reaction rates will be used built on the phenomenological kinetics introduced in Chemistry 260. Methods for determining and understanding solid state structures will be discussed, building on group theory introduced in Chemistry 461.

Section 200 is designed to introduce students to a more thorough, research oriented view of Physical Chemistry. Required for Honors Chemistry concentrators.

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CHEM 511. Materials Chemistry.

Section 100.

Instructor(s): M David Curtis (mdcurtis@umich.edu)

Prerequisites: Chem. 461 or equivalent, Biochem 415, Chem 430 or equivalent. Permission of course director. (3).

Credits: (3).

Course Homepage: No Homepage Submitted.

This course presents concepts in materials chemistry. The main topics covered include structure and characterization, macroscopic properties, and synthesis and processing.

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CHEM 521(511)/Biophysics 521. Biophysical Chemistry II.

Section 001.

Instructor(s): Erik R P Zuiderweg (zuiderwe@umich.edu)

Prerequisites: Chem. 461, Biol. Chem. 415, and Chem. 430 or equivalent; and permission of course director. (3).

Credits: (3).

Course Homepage: No Homepage Submitted.

See Biophysics 521.001.

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CHEM 526/Biology 526. Chemical Biology II.

Section 100.

Instructor(s): A. Ramamoorthy (ramamoor@umich.edu)

Prerequisites: Chem. 525. Prior or concurrent enrollment in Chemistry 402 or equivalent. (3).

Credits: (3).

Course Homepage: No Homepage Submitted.

This is the second of a two course sequence in Chemical Biology. The intent of these courses is to introduce students to the breadth of material contained within the inherently interdisciplinary "Chemical Biology" arena. The course has been designed to cross the traditional disciplinary boundaries of Chemistry. Thus, rather than having traditional bioorganic, bioinorganic, and biophysical sections, the course will focus on case studies chosen so that over the course of the two term sequence, all of the key concepts in the traditional chemical disciplines are discussed.

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CHEM 535/Macromolecular Science 535. Physical Chemistry of Macromolecules.

Section 100.

Instructor(s): Richard E Robertson (rer@umich.edu)

Prerequisites: Chem. 463. (3).

Credits: (3).

Course Homepage: No Homepage Submitted.

Among the topics covered are the thermodynamics of mixtures, the Flory-Huggins theory of polymer solutions, more modern theories of polymer solutions, the size and shape of macromolecular chains in solution and in bulk, and various techniques, like viscosity and light neutron scattering, for determining molecular size. In addition, rubber elasticity, polymer adsorption behavior, and polymer diffusion and scaling theories are covered. The course begins with a short, intense review of thermodynamics, but a grounding in the subject to at least the level of Chemistry 463 (Physical Chemistry) is required. The course grade is determined by the results of homework, two hourly exams, and the final exam. Besides the assigned text and the teacher's notes several original papers are also assigned for study.

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CHEM 536/Macromolecular Science 536. Laboratory in Macromolecular Chemistry.

Section 100 Meets with Chemistry 436.100.

Instructor(s): Paul Rasmussen (pgrasmsn@umich.edu)

Prerequisites: Chem. 535 or Phys. 418. (2). Laboratory fee ($50) required.

Credits: (2).

Lab Fee: Laboratory fee ($50) required.

Course Homepage: No Homepage Submitted.

Experimental methods for the study of macromolecular materials in solution and in bulk state.

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CHEM 541. Advanced Organic Chemistry.

Section 100.

Instructor(s): Edwin Vedejs (edved@umich.edu), William Roush (roush@umich.edu)

Prerequisites: Chem. 540. (3).

Credits: (3).

Course Homepage: No Homepage Submitted.

Synthetic organic chemistry. The scope and limitations of the more important synthetic reactions are discussed within the framework of multistep organic synthesis.

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CHEM 542. Applications of Physical Methods to Organic Chemistry.

Section 100.

Instructor(s): Adam Matzger (matzger@umich.edu)

Prerequisites: Chem. 260, 241/242, and 312. (3).

Credits: (3).

Course Homepage: No Homepage Submitted.

Applications of infrared, ultraviolet, and nuclear magnetic resonance spectroscopy; optical rotary dispersion, mass spectrometry; and other physical methods to the study of the structure and reactions of organic compounds.

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CHEM 570. Molecular Physical Chemistry.

Section 100.

Instructor(s): Henry Griffin (hcg@umich.edu)

Prerequisites: Chem. 461 and 463. (3).

Credits: (3).

Course Homepage: No Homepage Submitted.

See Chemistry 461.100.

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CHEM 575. Chemical Thermodynamics.

Section 100.

Instructor(s): John Gland (gland@umich.edu)

Prerequisites: Chem. 461. (3).

Credits: (3).

Course Homepage: No Homepage Submitted.

See Chemistry 463.100.

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CHEM 576. Statistical Mechanics.

Section 100.

Instructor(s): Raoul Kopelman (kopelman@umich.edu)

Prerequisites: Graduate standing and permission of instructor. (3).

Credits: (3).

Course Homepage: No Homepage Submitted.

No Description Provided

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CHEM 580. Molecular Spectra and Structure.

Section 100.

Instructor(s): David M Lubman (dmlubman@umich.edu)

Prerequisites: Chem. 570. (3).

Credits: (3).

Course Homepage: No Homepage Submitted.

Review of atomic spectra; rotational, vibration-rotation, and electronic spectra of diatomic and simple polyatomic molecules; and deduction of molecular parameters from spectra. Role of symmetry and representation theory generally. Different spectroscopies from nmr, and epr through ESCA.

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CHEM 598. IGERT Research Rotation.

Instructor(s): M. David Curtis (mdcurtis@umich.edu)

Prerequisites: Graduate standing. (3). (INDEPENDENT). May be repeated for credit four times.

Credits: (3).

Course Homepage: http://www.umich.edu/~mater/igert.html

In this program, we are seeking to bring together disciplines that are concerned with materials on a scale from the nanoscopic to the microscopic. These length scales for materials bridge the gap between the molecular (chemical) and the micron scale of devices. Chemists are increasingly concerned with complex "supramolecular" arrays, whereas the electronics engineers strive to decrease the sizes of their devices to molecular dimensions. The length scales associated with these disciplines are converging. Unfortunately, the language and laboratory skills that have evolved at the two extremes are quite different, making communication difficult. We envision a program that brings together these disciplines, creates a common language, and will produce a new generation of students skilled in molecularly designed materials.

The course helps students establish "critical literacy" in areas outside their core expertise is our proposed research group rotation (RGR). In the RGR, a student will select 3 research mentors with whom three, short-term research projects will be carried out. Each project will include a definition of the problem, a literature search, some laboratory work, and a final written report The student must interview a minimum of 5 prospective research mentors before choosing the three RGR mentors. The RGR student will take part in the full life of the host research laboratory, including participating in all group meetings, seminar activities, etc. of the host laboratory/department. At least one of the three research rotations must be outside the students home department and may include a summer term at a participating industrial or government laboratory.

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CHEM 599. CBI Research Rotation.

Instructor(s): James Coward (jkcoward@umich.edu)

Prerequisites: Graduate standing. (3). (INDEPENDENT).

Credits: (3).

Course Homepage: http://www.umich.edu/~michchem/chembio/

The Chemistry Biology Interface (CBI) Training Program, a unique multidisciplinary Ph.D. training program, focuses on the fundamental underlying chemical principles that govern all biological processes. This dynamic new program emphasizes mechanistic and synthetic aspects of research at the chemistry biology interface and leads to a Ph.D. degree in either Chemistry, Biological Chemistry, or Medicinal Chemistry. Students enrolled in the program will gain a broad appreciation of the chemical foundations of biology including synthesis, analysis, and theory and will be prepared to pursue research on a vast array of critical biological problems in academic or industrial settings. Three different University of Michigan departments Chemistry, Biological Chemistry, and Medicinal Chemistry have combined strengths to create this challenging new program. Each student's course of study is tailored to suit his or her individual goals and includes laboratory rotations in at least two of the participating University departments. To learn more about research in an industrial setting, students will also be encouraged to perform a rotation at the Parke-Davis Research Laboratories adjacent to the University's North Campus. The CBI Training Program offers students the unique opportunity to participate in laboratory rotations at the Parke-Davis Research Laboratories in the following areas: 1.Medicinal chemistry 2.Peptides 3.Structure-based design chemistry 4.Exploratory chemistry 5.Computational chemistry 6.Molecular modeling 7.Bioorganic chemistry 8.Structural biology 9.Analytical research 10.Combinatorial chemistry 11.Automated chemical synthesis

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CHEM 603/Biophysics 503. Biomolecular NMR: Structure & Dynamics in Solution & Solids.

Section 100.

Instructor(s): Erik R.P. Zuiderweg (zuiderwe@umich.edu), A. Ramamoorthy

Prerequisites: Graduate standing. (3).

Credits: (3).

Course Homepage: No Homepage Submitted.

See Biophysics 503.100.

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CHEM 616. Advanced Inorganic Chemistry.

Section 100.

Instructor(s): Mark Banaszak Holl (mbanasza@umich.edu)

Prerequisites: Chem. 507 and 570. Graduate standing. (3).

Credits: (3).

Course Homepage: No Homepage Submitted.

The application of theoretical principles to the experimental observations of modern inorganic chemistry: ligand field and molecular orbital theory of complex ions, structural chemistry, magnetic properties, ESR, Mossbauer spectra, NQR.

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CHEM 646. Separation Processes.

Section 100.

Instructor(s): Richard Sacks (rdsacks@umich.edu)

Prerequisites: Chem. 545 and Graduate standing. (3).

Credits: (3).

Course Homepage: No Homepage Submitted.

Requirements for analytical and preparational separations. Pertinent phase rule considerations; theoretical plate concepts; efficiency calculations for multistage processes; nature of adsorption. Theory and practice of (a) precipitation and crystallization, (b) volatilization and distillation, and (c) extraction, partition and distribution processes, especially ion-exchange, liquid-liquid extraction, and various types of adsorption and partition chromatography (gas, paper, thin-layer, etc.)

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CHEM 648. Spectroscopic and Electrochemical Analysis.

Section Analytical Spectroscopy and Imaging

Instructor(s): Michael Morris (mdmorris@umich.edu)

Prerequisites: Chem. 447 and Graduate standing. (3).

Credits: (3).

Course Homepage: https://coursetools.ummu.umich.edu/2001/winter/chem/648/100.nsf

Theory, practice, and application of spectrochemical techniques for analysis and research with emphasis on emission and absorption spectroscopy in the principal regions of electromagnetic spectrum.

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CHEM 648. Spectroscopic and Electrochemical Analysis.

Section 100.

Instructor(s): Michael D Morris (mdmorris@umich.edu)

Prerequisites: Chem. 447 and Graduate standing. (3).

Credits: (3).

Course Homepage: No Homepage Submitted.

No Description Provided

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CHEM 673/Biol. Chem. 673. Kinetics and Mechanism.

Prerequisites: Biol. Chem. 550 and calculus. Physical chemistry is recommended. (3).

Credits: (3).

Course Homepage: No Homepage Submitted.

This course will cover four broad topics in dept: ligand binding to macromolecules, transient kinetics, steady-state kinetics (AKA enzyme kinetics), and kinetic isotope effects. An emphasis will be placed on developing the key kinetic and thermodynamic concepts that govern the action of enzymes, and the thought processes required to deduce mechanism. Topics will be treated from both a "gut-feeling" and a mathematical perspective, and applications to real systems, including experimental methods, data analysis, and common errors/fallacies/abuses, will be considered in detail. Because computer methods for analyzing and simulating data have taken a prominent place in the field, the use of software from kinetics research will be emphasized through numerous "hands-on" exercises.

Graduate students and advanced undergraduates who are interested in the mechanics of enzymes, the design of inhibitors/drugs, enzyme structure/function studies, enzyme engineering, catalytic antibodies, or catalytic RNA will find this course valuable. Additionally, many of the concepts developed in this course have applications in the fields of protein folding, chemical biology, pharmacology, metabolic network analysis, and the quantitative study of virus and cell growth.

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CHEM 673/Biol. Chem. 673. Kinetics and Mechanism.

Section 001.

Instructor(s): Carol A Fierke (fierke@umich.edu)

Prerequisites: Biol. Chem. 550 and calculus. Physical chemistry is recommended. (3).

Credits: (3).

Course Homepage: No Homepage Submitted.

This course will cover the investigation of enzyme mechanisms with an emphasis on kinetic and thermodynamic methodology, including: ligand binding to macromolecules, transient kinetics, steady-state kinetics, and kinetic isotope effects. The key kinetic and thermodynamic concepts that govern the action of enzymes, and the thought processes required to deduce catalytic and kinetic mechanisms will be explored. Topics will be treated from both a "gut-feeling" and a mathematical perspective, and applications to real systems, including experimental methods, data analysis, and common errors/fallacies/abuses, will be considered in detail. Because computer methods for analyzing and simulating data have taken a prominent place in the field, the use of software from kinetics research will be emphasized through numerous "hands-on" exercises.

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CHEM 720. Chemical Sciences at the Interface of Education Seminar.

Section 100 Topic?

Instructor(s): Brian P Coppola (bcoppola@umich.edu)

Prerequisites: Permission if instructor. Graduate standing. (1).

Credits: (1).

Course Homepage: http://www.umich.edu/~michchem/csie/

Special seminar designed to discuss effective teaching strategies and methods to assess teaching effectiveness. Supervised teaching experiences in conjunction with an accelerated entrance into the research laboratory enable CSIE students to gain experience in curriculum revision for undergraduate lecture and laboratory courses.

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CHEM 800. Seminar in Chemical Biology.

Section 100 Topic?

Instructor(s): E Neil G Marsh (nmarsh@umich.edu)

Prerequisites: Graduate standing. (2). May be repeated for a total of 12 credits.

Credits: (2).

Course Homepage: http://www.umich.edu/~chembio/

No Description Provided

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CHEM 801. Seminar in Analytical Chemistry.

Section 100 Topic?

Instructor(s): Adon A Gordus (gordus@umich.edu)

Prerequisites: Graduate standing. (2).

Credits: (2).

Course Homepage: No Homepage Submitted.

No Description Provided

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CHEM 802. Seminar in Inorganic Chemistry.

Section 100 Topic?

Instructor(s): Paul G Rasmussen (pgrasmsn@umich.edu)

Prerequisites: Graduate standing. (2).

Credits: (2).

Course Homepage: No Homepage Submitted.

No Description Provided

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CHEM 803. Seminar in Organic Chemistry.

Section 100 Topic?

Instructor(s): William Hardy Pearson (wpearson@umich.edu)

Prerequisites: Graduate standing. (2).

Credits: (2).

Course Homepage: No Homepage Submitted.

No Description Provided

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CHEM 804. Seminar in Physical Chemistry.

Section 100 Topic?

Instructor(s): Raoul Kopelman (kopelman@umich.edu)

Prerequisites: Graduate standing. (2).

Credits: (2).

Course Homepage: No Homepage Submitted.

No Description Provided

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CHEM 806. Departmental Tuesday Seminar.

Section 100 Topic?

Instructor(s): Masato Koreeda (koreeda@umich.edu)

Prerequisites: Graduate standing. (1).

Credits: (1).

Course Homepage: No Homepage Submitted.

No Description Provided

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CHEM 807. Departmental Thursday Seminar.

Section 100 Topic?

Instructor(s): Richard D Sacks (rdsacks@umich.edu)

Prerequisites: Graduate standing. (1).

Credits: (1).

Course Homepage: No Homepage Submitted.

No Description Provided

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CHEM 808. Departmental Friday Seminar.

Section 100 Topic?

Instructor(s): E Neil G Marsh (nmarsh@umich.edu)

Prerequisites: Graduate standing. (1).

Credits: (1).

Course Homepage: No Homepage Submitted.

No Description Provided

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CHEM 895. Research in Chemistry.

Prerequisites: Approval of Graduate Committee. Graduate standing. (1-8). (INDEPENDENT).

Credits: (1-8; 1-4 in the half-term).

Course Homepage: No Homepage Submitted.

No Description Provided

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CHEM 990. Dissertation/Precandidate.

Prerequisites: Election for dissertation work by doctoral student not yet admitted as a Candidate. Graduate standing. (1-8). (INDEPENDENT). May be repeated for credit.

Credits: (1-8; 1-4 in the half-term).

Course Homepage: No Homepage Submitted.

Election for dissertation work by doctoral student not yet admitted as a Candidate.

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CHEM 993. Graduate Student Instructor Training Program.

Prerequisites: Must have Teaching Assistant award. Graduate standing. (1).

Credits: (1).

Course Homepage: No Homepage Submitted.

A seminar for all beginning graduate student instructors, consisting of a two day orientation before the term starts and periodic workshops/meetings during the Winter Academic Term. Beginning graduate student instructors are required to register for this class.

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CHEM 995. Dissertation/Candidate.

Prerequisites: Graduate School authorization for admission as a doctoral Candidate. Graduate standing. (8). (INDEPENDENT). May be repeated for credit.

Credits: (8; 4 in the half-term).

Course Homepage: No Homepage Submitted.

Graduate School authorization for admission as a doctoral Candidate. N.B. The defense of the dissertation (the final oral examination) must be held under a full term Candidacy enrollment period.

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Undergraduate Course Listings for CHEM.


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