College of LS&A

Winter Academic Term 2003 Graduate Course Guide

Note: You must establish a session for Winter Academic Term 2003 on wolverineaccess.umich.edu in order to use the link "Check Times, Location, and Availability". Once your session is established, the links will function.

Courses in Molecular, Cellular, and Developmental Biology


This page was created at 8:37 AM on Thu, Feb 6, 2003.

Winter Academic Term, 2003 (January 6 - April 25)

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MCDB 400(BIOLOGY 400). Advanced Research.

Instructor(s):

Prerequisites: 12 credits of biology, 3.0 average in science, and permission of faculty member in biology. (1-3). (INDEPENDENT). May be repeated for credit for a maximum of 9 credits. Continuing Course. Y grade can be reported at end of the first-term to indicate work in progress. At the end of the second term of MCDB 400, the final grade is posted for both term's elections.

Credits: (1-3).

Course Homepage: No homepage submitted.

Intended for those engaged in original research at an advanced level. This course number is most frequently elected by senior Honors students who have completed MCDB 300 and who are completing their research and writing their thesis. A final paper is required. (Refer to the description of MCDB 300 for more information.)

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: 5, Permission of Department

MCDB 413(BIOLOGY 413). Plant Molecular Biology Laboratory.

Section 001.

Instructor(s): Eran Pichersky (lelx@umich.edu)

Prerequisites: BIOLOGY 310 or 311, or BIOLCHEM 415; and BIOLOGY 305. (3). Satisfies a Biology laboratory requirement. Laboratory fee ($70) required. May not be repeated for credit.

Credits: (3).

Lab Fee: Laboratory fee ($70) required.

Course Homepage: No homepage submitted.

This is a project lab in which students learn to identify and analyze plant genes and gene products using the latest techniques of molecular biology. Emphasis will be on genes encoding unique plant characteristics. Students will first isolate genes from DNA libraries of various plant species. They will then analyze the sequence of genes they have isolated by DNA sequencing, and will characterize their copy number and expression levels by various techniques such as Southern blots, Northern blots, etc. The genes will then be manipulated to produce the gene products (i.e., proteins) in a bacterial system.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: 1

MCDB 428(BIOLOGY 428). Cell Biology.

Section 001 MIDTERM EXAMS WILL BE HELD TUES, FEB 4, AND MAR 18, 6-8 PM.

Instructor(s): James Bardwell (jbardwel@umich.edu) , Kenneth M Cadigan (cadigan@umich.edu)

Prerequisites: BIOLOGY 305; and BIOLOGY 310 or 311, or BIOLCHEM 415. Students with credit for MCDB 320 must obtain permission of instructor. (4). May not be repeated for credit.

Credits: (4).

Course Homepage: http://coursetools.ummu.umich.edu/2003/winter/mcdb/428/001.nsf

MCDB 428 is designed to provide students with a comprehensive overview of the biology of eukaryotes and prokaryotes at the cellular and molecular level. This course is intended for upper-level undergraduates and graduate students. The information is presented at a level that requires students to integrate information from their other biology, chemistry, and biochemistry courses. Topics include: cell structure and function; cell membranes; intracellular organelles and cytoskeleton; inter- and intra-cellular signaling; cell development and cell cycle. Students will be expected to integrate the scientific data presented in class as well as to read and interpret basic research drawn from the current scientific literature. Grades will be based on four exams and the discussion section. Textbook: Molecular Biology of the Cell by Alberts et al. Garland Science.

Contact jbardwel@umich.edu or cadigan@umich.edu if you have questions regarding the course.

Check Times, Location, and Availability Cost: 2 Waitlist Code: 1

MCDB 429(BIOLOGY 429). Laboratory in Cell and Molecular Biology.

Section 001.

Instructor(s): Kenneth J Balazovich (kbalazo@umich.edu)

Prerequisites: MCDB 427 or 428, or concurrent enrollment in MCDB 428. No credit granted to those who have completed or are enrolled in BIOLCHEM 416 or 516. (3). Satisfies a Biology laboratory requirement. Laboratory fee ($70) required. May not be repeated for credit.

Credits: (3).

Lab Fee: Laboratory fee ($70) required.

Course Homepage: http://coursetools.ummu.umich.edu/2003/winter/mcdb/429/001.nsf

This laboratory course encompasses a broad spectrum of common methods and theory essential to Cellular and Molecular Biology concentrations. The one hour lecture each week is used to introduce methodology and techniques that will be encountered in the lab. Two, four-hour weekly lab sessions are arranged in a project-based format. The projects include several kinds of microscopy, cellular organelle isolation, gel electrophoresis, Western bottting, column chromatography and tissue culture, in addition to molecular biology methods such as plasmid construction, transfection, polymerase chain reaction, and Southern blotting. Grades are based on three exams, laboratory quizzes and a semester-long grant proposal project that may be completed individually or in a self-organized group. This course can be used to satisfy requirements for the Cell and Molecular Biology Concentration and the Biology Concentration.

Textbook:
Laboratory DNA Science (Bloom et al.) Mandatory.
Molecular Biology of the Cell (Alberts et al.) Suggested.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: 1

MCDB 430(BIOLOGY 430). Molecular Biology of Plants.

Section 001.

Instructor(s): Eran Pichersky (lelx@umich.edu)

Prerequisites: BIOLOGY 305; and 310 or 311, or BIOLCHEM 415. (3). May not be repeated for credit.

Credits: (3).

Course Homepage: No homepage submitted.

The topic of this course is major advances in understanding molecular processes in plants, and the contribution of molecular biological techniques to these advances. The course is intended for advanced undergraduates and beginning graduate students. The course will begin with an overview of the basic techniques of plant molecular biology such as cloning and sequencing of DNA, transformation, and analysis of gene expression. We will then examine selected topics in detail, including genome structure and the evolution of genes, proteins, and biochemical pathways, photoreception, photosynthesis and respiration, and the synthesis of secondary products. We will read and then discuss research publications in class. Student performance will be evaluated on the basis of class presentations and participation, and two take-home examinations.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: 1

MCDB 435(BIOLOGY 435). Intracellular Trafficking.

Section 001.

Instructor(s): Jesse C Hay (jessehay@umich.edu)

Prerequisites: BIOLOGY 305, BIOLOGY 310, 311, or BIOLCHEM 415, and MCDB 428. (3). May not be repeated for credit.

Credits: (3).

Course Homepage: No homepage submitted.

This is an advanced discussion-oriented course covering the latest research in the field of intracellular trafficking. Topics covered include molecular basis of secretion, vesicle transport, protein targeting, molecular motors, and organelle biogenesis. Students will be presented lectures providing them with enough background to understand specific questions and gaps in our knowledge of intracellular trafficking mechanisms. Most of the class time, however, will be spent discussing current research papers from the primary literature. The emphasis will be on the critical evaluation of these studies' experimental approaches, interpretation of data, and conclusions.

This course is intended for students with a serious interest in cell biological research. It is intended for advanced, graduate school-bound undergraduates, and first- and second-year graduate students. There will be two 1.5 hour class periods per week. Students will be assigned problem sets to ensure that they have done the reading before class and have thought sufficiently about the issues involved. The course will also require participation in discussion. In addition, each student will have to present at least one research paper to the class, explain the questions being addressed, techniques, pitfalls, etc.

Check Times, Location, and Availability Cost: 1 Waitlist Code: 1

MCDB 526(BIOLOGY 526) / CHEM 526. Chemical Biology II.

Section 100.

Instructor(s): E Neil G Marsh (nmarsh@umich.edu)

Prerequisites: MCDB 525. Prior or concurrent enrollment in CHEM 402 or equivalent. (3). May not be repeated for credit.

Credits: (3).

Course Homepage: No homepage submitted.

See Chemistry 526.100.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: No Data Given.

MCDB 589(BIOLOGY 589). Mechanisms of Microbial Evolution.

Section 001.

Instructor(s): Julian P Adams (julian@umich.edu)

Prerequisites: BIOLOGY 305. (3). May not be repeated for credit.

Credits: (3).

Course Homepage: No homepage submitted.

Topics covered include the nature of microbial populations, laboratory populations, mutator loci in clonal populations, and coevolution.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: 1

MCDB 630(BIOLOGY 630) / MICRBIOL 630 / CMBIOL 630 / HUMGEN 630 / PHRMACOL 630. Genetics Short Course.

Section 001 Genetics Training Grant/CMB Short Course. [Drop/Add deadline=January 24].

Instructor(s): Miriam H Meisler (meislerm@umich.edu)

Prerequisites: Graduate standing. (1). May be elected more than once for credit.

Mini/Short course

Credits: (1).

Course Homepage: No homepage submitted.

No Description Provided. Contact the Department.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: No Data Given.


Undergraduate Course Listings for MCDB.


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This page was created at 8:37 AM on Thu, Feb 6, 2003.


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