College of LS&A

Winter Academic Term 2004 Graduate Course Guide

Note: You must establish a session for Winter Academic Term 2004 on wolverineaccess.umich.edu in order to use the link "Check Times, Location, and Availability". Once your session is established, the links will function.

Courses in Molecular, Cellular, and Developmental Biology


This page was created at 6:18 PM on Wed, Jan 21, 2004.

Winter Academic Term 2004 (January 6 - April 30)


MCDB 400(BIOLOGY 400). Advanced Research.

Instructor(s):

Prerequisites: 12 credits of biology, 3.0 average in science, and permission of faculty member in biology. (1-3). (INDEPENDENT). May be repeated for credit for a maximum of 9 credits. Continuing Course. Y grade can be reported at end of the first-term to indicate work in progress. At the end of the second term of MCDB 400, the final grade is posted for both term's elections.

Credits: (1-3).

Course Homepage: No homepage submitted.

Intended for those engaged in original laboratory research at an advanced level. This course number is most frequently elected by senior Honors students who have completed MCDB 300 and who are completing their research and writing their thesis. A final paper is required. (Refer to the description of MCDB 300 for more information.)

The work in this course may continue for two academic terms. A 'Y' grade can be reported at the end of the first-term to indicate work in progress. At the end of the second term of MCDB 400, the final grade is posted for both term's elections. Students interested in MCDB 400 should obtain the brochure MCDB Department Policies on Undergraduate Research from the Undergraduate Biology Program Office (1111 Natural Science Bldg).

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: 5, Permission of instructor

MCDB 413(BIOLOGY 413). Plant Molecular Biology Laboratory.

Section 001.

Instructor(s): Eran Pichersky (lelx@umich.edu)

Prerequisites: BIOLOGY 310 or 311, or BIOLCHEM 415; and BIOLOGY 305. (3). May not be repeated for credit. Satisfies a Biology laboratory requirement. Laboratory fee ($70) required.

Credits: (3).

Lab Fee: Laboratory fee ($70) required.

Course Homepage: No homepage submitted.

This is a project lab in which students learn to identify and analyze plant genes and gene products using the latest techniques of molecular biology. Emphasis will be on genes encoding unique plant characteristics. Students will first isolate genes from DNA libraries of various plant species. They will then analyze the sequence of genes they have isolated by DNA sequencing, and will characterize their expression levels by various techniques. The genes will then be manipulated to produce the gene products (i.e., proteins) in a bacterial system.

Biochemistry and Molecular Biology of Plants. Buchanan, Gruissem, Jones. Publisher: John Wiley & sons. ISBN 0943088399

Check Times, Location, and Availability Cost: 3 Waitlist Code: 1

MCDB 428(BIOLOGY 428). Cell Biology.

Section 001 — MIDTERM EXAMS WILL BE HELD WEDNESDAYS, FEBRUARY 4TH AND MARCH 17TH, 6-8 PM.

Instructor(s): Jesse C Hay (jessehay@umich.edu) , Kenneth M Cadigan (cadigan@umich.edu)

Prerequisites: BIOLOGY 305; and BIOLOGY 310 or 311, or BIOLCHEM 415. (4). May not be repeated for credit. Students with credit for MCDB 320 must obtain permission of instructor.

Credits: (4).

Course Homepage: No homepage submitted.

MCDB 428 is designed to provide students with a comprehensive overview of the biology of eukaryotes and prokaryotes at the cellular and molecular level. This course is intended for upper-level undergraduates and graduate students. The information is presented at a level that requires students to integrate information from their other biology, chemistry, and biochemistry courses. Topics include: cell structure and function; cell membranes; intracellular organelles and cytoskeleton; inter- and intra-cellular signaling; cell development; and cell cycle. Students will be expected to integrate the scientific data presented in class as well as to read and interpret basic research drawn from the current scientific literature. Grades will be based on three exams and the discussion section.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: 1

MCDB 429(BIOLOGY 429). Laboratory in Cell and Molecular Biology.

Section 001.

Instructor(s): Kenneth J Balazovich (kbalazo@umich.edu)

Prerequisites: MCDB 427 or 428, or concurrent enrollment in MCDB 428. (3). May not be repeated for credit. No credit granted to those who have completed or are enrolled in BIOLCHEM 416 or 516. Satisfies a Biology laboratory requirement. Laboratory fee ($70) required.

Credits: (3).

Lab Fee: Laboratory fee ($70) required.

Course Homepage: http://coursetools.ummu.umich.edu/2004/winter/mcdb/429/001.nsf

This laboratory course encompasses a broad spectrum of common methods and theory essential to Cellular and Molecular Biology concentrations. The 90-minute lecture each week is used to introduce methodology and techniques that will be encountered in the lab. Two weekly lab sessions are arranged in a project-based format. The projects include several kinds of microscopy, cellular organelle isolation, gel electrophoresis, Western blotting, column chromatography and tissue culture, in addition to molecular biology methods such as plasmid construction, transfection, polymerase chain reaction, and Southern blotting. Grades are based on three exams, laboratory quizzes and a semester-long grant proposal project that may be completed individually or in a self-organized group. This course can be used to satisfy requirements for the Cell and Molecular Biology Concentration and the Biology Concentration.

Textbook:
Mandatory: Laboratory DNA Science (Bloom, et al. )
Suggested: Molecular Biology of the Cell (Alberts, et al. )

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: 1

MCDB 430(BIOLOGY 430). Molecular Biology of Plants.

Section 001.

Instructor(s): Charles F Yocum (cyocum@umich.edu)

Prerequisites: BIOLOGY 305; and 310 or 311, or BIOLCHEM 415. (3). May not be repeated for credit.

Credits: (3).

Course Homepage: No homepage submitted.

The topic of this course is major advances in understanding molecular processes in plants, and the contribution of molecular biological techniques to these advances. The course is intended for advanced undergraduates and beginning graduate students. The course will begin with an overview of the basic techniques of plant molecular biology such as cloning and sequencing of DNA, transformation, and analysis of gene expression. We will then examine selected topics in detail, including proteins, biochemical pathways, photoreception, photosynthesis, and respiration. We will read and then discuss research publications in class. Student performance will be evaluated on the basis of class participation, two take-home examinations, and a term paper.

Biochemistry and Molecular Biology of Plants. Buchanan, Gruissen, Jones. (John Wiley & Sons.) (softbound).

Check Times, Location, and Availability Cost: 3 Waitlist Code: No Data Given.

MCDB 435(BIOLOGY 435). Intracellular Trafficking.

Section 001.

Instructor(s): Jesse C Hay (jessehay@umich.edu)

Prerequisites: BIOLOGY 305, BIOLOGY 310, 311, or BIOLCHEM 415, and MCDB 428. (3). May not be repeated for credit.

Credits: (3).

Course Homepage: No homepage submitted.

This is an advanced discussion-oriented course covering the latest research in the field of intracellular trafficking. The course is intended for students with a serious interest in cell biological research. It is intended for advanced, graduate school-bound undergraduates, and first- and second-year graduate students. Topics covered include molecular basis of secretion, vesicle transport, protein targeting, molecular motors, and organelle biogenesis. Students will be presented lectures providing them with enough background to understand specific questions and gaps in our knowledge of intracellular trafficking mechanisms. Most of the class time, however, will be spent discussing current research papers from the primary literature. The emphasis will be on the critical evaluation of these studies' experimental approaches, interpretation of data, and conclusions. There will be two 1.5-hour class periods per week. Students will be assigned problem sets to ensure that they have done the reading before class and have thought sufficiently about the issues involved. The course also will require participation in discussion. In addition, each student will have to present at least one research paper to the class, explain the questions being addressed, techniques, pitfalls, etc.

Check Times, Location, and Availability Cost: 1 Waitlist Code: 1

MCDB 469(BIOLOGY 469). Signal Transduction.

Section 001.

Instructor(s): Kenneth M Cadigan (cadigan@umich.edu)

Prerequisites: MCDB 427 or 428. (3). May not be repeated for credit.

Credits: (3).

Course Homepage: No homepage submitted.

This course will cover selected aspects of animal signal transduction, focusing on critical reading and presentation of primary research papers. It will also emphasize the importance of combining genetic and biochemical approaches to gain a better understanding of cellular processes. Topics will include TGF and Notch signaling, MAP kinase cascades, and the tumor suppressor APC. Grades will be determined by discussion in class, an oral presentation and two written assignments. The course is intended for junior or senior CMB concentrators (who have taken either MCDB 427 or 428) and graduate students. The class will meet twice weekly for 90 minutes.

Contact the instructor — cadigan@umich.edu with any questions regarding the course.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: 1

MCDB 615(BIOLOGY 615). Topics in Cellular and Molecular Biology.

Section 001 — Topic?

Instructor(s): John Y Kuwada (kuwada@umich.edu), Anuj Kumar, Matthew R Chapman

Prerequisites: MCDB 427 and 428; Graduate standing and permission of instructor. (3). May be elected twice for credit.

Credits: (3).

Course Homepage: No homepage submitted.

No Description Provided. Contact the Department.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: 5, Permission of Instructor

MCDB 700. Advanced Studies.

Instructor(s):

Prerequisites: Sixteen hour of biology and permission of instructor. (1-8). (INDEPENDENT). May not be repeated for credit.

Credits: (1-8).

Course Homepage: No homepage submitted.

No Description Provided. Contact the Department.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: 5, Permission of instructor

MCDB 800(BIOLOGY 800). Biology Seminars.

Section 001 — TOPICS IN DEVELOPMENTAL NEUROBIOLOGY.

Instructor(s): Richard I Hume (rhume@umich.edu)

Prerequisites: Graduate standing and permission of instructor. (1). May be elected more than once for credit.

Credits: (1).

Course Homepage: No homepage submitted.

No Description Provided. Contact the Department.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: 5, Permission of Instructor

MCDB 800(BIOLOGY 800). Biology Seminars.

Section 002 — PLANT CELL AND MOLECULAR BIOLOGY.

Instructor(s): Jianming Li (jian@umich.edu)

Prerequisites: Graduate standing and permission of instructor. (1). May be elected more than once for credit.

Credits: (1).

Course Homepage: No homepage submitted.

No Description Provided. Contact the Department.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: 5, Permission of Instructor

MCDB 801(BIOLOGY 801). Supervised Teaching.

Instructor(s):

Prerequisites: Graduate standing and permission of instructor. Appointment as Teaching Assistant in Biology. (2; 1 credit for GSI Training course). (INDEPENDENT). May not be repeated for credit.

Credits: (2; 1 credit for GSI Training course).

Course Homepage: No homepage submitted.

Seminars, demonstrations, and orientation for college teaching in biology. Available for all pre-candidate teaching assistants.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: 5, Permission of instructor

MCDB 990(BIOLOGY 990). Dissertation/Precandidate.

Instructor(s):

Prerequisites: Election for dissertation work by doctoral student not yet admitted as a Candidate. Graduate Standing. (1-8). (INDEPENDENT). May be repeated for credit. This course has a grading basis of "S" or "U."

Credits: (1-8; 1-4 in the half-term).

Course Homepage: No homepage submitted.

Election for dissertation work by doctoral student not yet admitted as a Candidate.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: 5, Permission of Department

MCDB 995(BIOLOGY 995). Dissertation/Candidate.

Instructor(s):

Prerequisites: Graduate School authorization for admission as a doctoral Candidate (Prerequisites enforced at registration). (8). (INDEPENDENT). May be repeated for credit. This course has a grading basis of "S" or "U."

Credits: (8; 4 in the half-term).

Course Homepage: No homepage submitted.

Graduate School authorization for admission as a doctoral Candidate. N.B. The defense of the dissertation (the final oral examination) must be held under a full term Candidacy enrollment period.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: No Data Given.


Undergraduate Course Listings for MCDB.


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This page was created at 6:18 PM on Wed, Jan 21, 2004.


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