This course is team-taught and is the second of a two-term biophysical chemistry series, BIOPHYS 520/521, but it can be taken as a stand-alone course. BIOPHYS 521 provides an overview of the theory and application of spectroscopical techniques of UV/Vis, IR, Fluorescence, Single Molecule Detection, CD, and NMR. Other topics covered include
X-ray crystallography, computational methods, light scattering, ultracentrifugation. When possible, hands-on opportunities in applying some of these techniques will be offered.
Textbooks:
"Biophysical Chemistry", part 1, Canton, 0716711885, publ
Freeman "Biophysical Chemistry", part 2, Canton, 0716711923, publ
Freeman "Proteins", Creighton, 0716732688, publ Freeman
Advisory Prerequisite: PHYSICS,CHEM 461/430 or equivalent, BIOLCHEM 415, permission of instructor
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This one credit course will consist of lectures and discussions pertaining to receptor-ligand interactions in the immune system. The goal of the course is to provide students a broad overview of the structural basis of immune function by reviewing recent literature.
Advisory Prerequisite: PHYSICS,BIOLOGY 305 and BIOLCHEM 415 and MCDB 436/MICRBIOL 502; and graduate standing; undergraduates with permission of instructor.
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Students in Molecular Biophysics fulfill the requirements for a Ph.D. in either Biological Chemistry, Biophysics, Chemistry, or Physics. Training in Molecular Biophysics aims to develop independent investigators who will contribute in significant ways to advances in understanding structural and cellular biology at the molecular level. Students concentrating in Molecular Biophysics elect courses in areas such as protein structure and function, techniques in NMR and crystallography, and spectroscopic methods.
Advisory Prerequisite: Graduate standing and permission of instructor.
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The main focus is to offer research training in the applications of physics-based techniques to biological systems ranging in complexity from single molecules to whole cells and tissues.
Advisory Prerequisite: PHYSICS,Research rotations: Primarily for students in the Biophysics Graduate Program. Graduate standing and permission of instructor.
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