Courses in Biological Chemistry (Division 517)

Courses in the Department of Biological Chemistry are listed in the Time Schedule as part of the Medical School's offerings in the subsection Biological Chemistry. The following count as LS&A courses for LS&A degree credit.

415. Introductory Biochemistry. Two terms of organic chemistry. No credit granted to those who have completed or are enrolled in Biol. 310 or 311, or Chem. 451/452. (3-4). (Excl). (BS).
A one term introductory biochemistry course that covers the biochemistry of the living state, the chemistry of biomolecules, energy transformations and chemical reactions in living cells, function of the immune system and action of hormones, and self-regulation and self-replication of living organisms. Students may elect a fourth credit hour by attending an extra series of lectures once a week, and writing a research paper.
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Courses 570-577 each last one month

573. Enzyme Kinetics and Ligand Binding. Biol. Chem. 570 or equivalent. Physical chemistry is strongly recommended. (1). (Excl). (BS).
A detailed examination of ligand binding and steady-state kinetics, including an introduction to rapid reaction kinetics. Problem sets are an important component of the course. Cost:2 WL:4
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574. Catalysis. Biol. Chem. 570 and 573. Physical chemistry is strongly recommended. (1). (Excl). (BS).
General principles of enzyme catalysis, including general acid and base catalysis, covalent catalysis, and strain and distortion aspects of catalysis. Selected examples to illustrate those principles will include proteases, discussing kinetics, covalent intermediates, mechanism of catalysis at the active site, and inhibition. Other topics include isotope effects, stereochemistry, cofactors, and prosthetic groups involved in catalysis with appropriate enzymatic examples such as redox transformations, pyridoxal phosphate catalyzed reactions, and phosphoryl transfer. Cost:2 WL:4
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