Winter '99 Course Guide

Courses in Biology (Division 328)

Winter Term, 1999 (January 6-April 29, 1999)

Take me to the Winter Term '99 Time Schedule for Biology.


Biol. 100. Biology for Nonscientists.

Section 001 Primarily A Distribution Course; Not Appropriate for Students Who Plan To Concentrate in Biology or Other Science Programs

Instructor(s): John Burch (jbburch@umich.edu)

Prerequisites & Distribution: Not open to those with Advanced Placement or "Departmental" credit in biology, nor to those concentrating in the biological sciences. Credit is granted for a combined total of 12 credits elected in introductory biology. (4). (NS). (BS).

Credits: (4).

Course Homepage: No Homepage Submitted.

Biology 100 is a one-term course designed to introduce students to current biological concepts. The course consists of three hours of lecture per week plus a coordinated discussion session which occupies two hours per week. Biology 100 provides an introduction to some general principles of biology and concentrates on the areas of cell biology, genetics, evolution, and environmental biology. A major objective of this course is to point out to students the nature of the scientific process and illustrate the uses and non-uses of science in contemporary life. Wherever possible, the ethical and social implications of contemporary scientific effort will be discussed.

This course is designed for students with a minimal background in the biological sciences but we do assume some exposure to biology at the high school level. Discussion sections enroll 20 students and are taught by graduate student teaching assistants. In the discussion section, students have the opportunity to review material presented in lecture and participate in discussions of issues raised in the lecture segment.

Check Times, Location, and Availability Cost: 3 Waitlist Code: 1; you MUST attend the first discussion section to claim your place in the course

Biol. 102. Practical Botany.

Instructor(s): George Estabrook (gfred@umich.edu)

Prerequisites & Distribution: Credit is granted for a combined total of 12 credits elected in introductory biology. (4). (NS). (BS). Laboratory fee ($50) required.

Credits: (4).

Lab Fee: Laboratory fee ($50) required.

Course Homepage: No Homepage Submitted.

Biology 102 is an introductory course about plants and how they are used by people. Each week there are two one-hour lectures, one afternoon two-and-a-half hour lab at the Botanical Gardens, and one one-hour discussion on main campus. Lecture topics include: what plants look like; how plants work; how they make their living in nature; using this knowledge to landscape your house, caring for your house plants, and growing your gardens; medicinal plants; plant breeding; agriculture and food; environmental and psychological importance of plants. In the lab, each student has his/her own personal space in a greenhouse to grow plants that can be taken home during the term. Lab activities may include: looking at plants; planting seeds; growing plants; rooting cuttings; making medicinal salve; testing soil; preserving garden produce; making hanging baskets; using plant dyes; making bonsai; grafting plants; making wine; and forcing bulbs to flower. The text, An Illustrated Guide to Gardening, will be useful throughout your life. Only prerequisite is your interest in plants. You MUST attend the first lecture and first lab for which you are registered to retain your place; your attendance throughout the term determines part of your grade. Please put your name on the waitlist immediately if you cannot register before the course closes.

Check Times, Location, and Availability Cost: 2 Waitlist Code: 5, Sign waitlist near 2117 Natural Science Building.

Biol. 118. AIDS and other Health Crises.

Instructor(s): Robert Bender (rbender@umich.edu)

Prerequisites & Distribution: (4). (NS). (BS).

Credits: (4).

Course Homepage: No Homepage Submitted.

This course is designed for non-majors with a minimal background in the sciences. The course focuses on the concepts of health and disease and their impact on society. It also focuses on the impacts of the structures and attitudes of society on health and disease. We will examine a number of health crises, especially AIDS, from the multiple viewpoints of science, medicine, public health, law, social prejudices, mass media, high culture, and the historical effects of health and disease. Specific topics will include extensive discussions of the tragic story of Mary Mallon (Typhoid Mary) and Syphilis from 1880 to the present, as well as some discussion of cholera, tuberculosis, influenza, and the black death. About one third of the course will be devoted to AIDS. The course consists of two 90-minute lectures per week and a 1-hour discussion led by a graduate student instructor. Grades are based on five in-class exams and an optional final exam.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: No Data Given.

Biol. 120. First Year Seminar in Biology.

Instructor(s): John Lehman (jtlehman@umich.edu)

Prerequisites & Distribution: Only first-year students, including those with sophomore standing, may pre-register for First-Year Seminars. All others need permission of instructor. (3). (NS). (BS).

First-Year Seminar

Credits: (3).

Course Homepage: No Homepage Submitted.

The purpose of the first-year seminar is to permit a small group of undergraduates to meet regularly with a full professor during their first year. This is a discussion format, not a lecture, and students are expected to participate by asking questions and sharing opinions. Reading assignments outside of class time will come from library sources and will require the use of electronic search tools that you will learn about. The main point is to gain an understanding of the types of scientific knowledge that are needed to solve environmental problems, and to develop an appreciation of problem-solving skills. Included at no extra cost will be some practical philosophy about science and about undergraduate education at large research universities. No assigned textbook.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: No Data Given.

Biol. 120. First Year Seminar in Biology.

Section 002 Emerging and Re-emerging Infectious Diseases

Instructor(s): Reinarz

Prerequisites & Distribution: Only first-year students, including those with sophomore standing, may pre-register for First-Year Seminars. All others need permission of instructor. (3). (NS). (BS).

First-Year Seminar

Credits: (3).

Course Homepage: No Homepage Submitted.

During the age of discovery of antibiotics, medical scientists often expressed confidence in winning the "War on Disease." Microbes have prevailed, however, and recent news is filled with accounts of recurring and previously unknown threats. This seminar will examine clinical victories and failures to contain infectious diseases. Models will include polio, influenza, HIV infections, multi-drug resistant tuberculosis, and Ebola. This course is limited to 20 first-year students. The class will be primarily discussion format and will include oral presentations by students. The grade will be based on class discussion, group presentation, and written assignments.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: No Data Given.

Biol. 124. Cells, Cancer, and Society.

Instructor(s): Lewis Kleinsmith (lewisk@umich.edu)

Prerequisites & Distribution: Not open to biology concentrators. No credit granted to those who have completed or are enrolled in Biol. 224. Credit is granted for a combined total of 12 credits elected in introductory biology. (3). (NS). (BS).

Credits: (3).

Course Homepage: No Homepage Submitted.

This course uses lecture and discussion sections to introduce non-science concentrators to the science of cancer biology, and has no prerequisites. The term will be divided into three basic sections. (1) First we will describe the basic concepts in cell and molecular biology that must be understood before students can comprehend the mechanisms that lead to the development of cancer. (2) Next we will use this information to explain current ideas regarding the causes, prevention, and treatment of cancer. (3) And finally, we will discuss the relevance of this information to social issues such as governmental regulation of environmental cancer-causing agents. Emphasis will be placed on the critical thinking skills that are needed to evaluate the claims that continually appear in the news media regarding the latest "breakthroughs" in cancer research. Students will be evaluated through three examinations and a term paper project.

Check Times, Location, and Availability Cost: 1 Waitlist Code: 1

Biol. 162. Introductory Biology.

Instructor(s): Marcus Ammerlaan (mcammer@umich.edu)

Prerequisites & Distribution: Prior or concurrent enrollment in Chemistry 130. No credit granted to those who have completed or are enrolled in Biology 152 or 195. Credit is granted for a combined total of 12 credits elected in introductory biology. (5). (NS). (BS). Laboratory fee ($68) required.

Credits: (5).

Lab Fee: Laboratory fee ($68) required.

Course Homepage: http://biology.lsa.umich.edu/courses/bio162/bio162.html

A one-term introductory course intended for concentrators in biology, other science programs, or preprofessional studies. Other suitably prepared students wishing detailed coverage of biology are also welcome. The aims of Biology 162 are: (1) to provide factual and conceptual knowledge; (2) to give an integrated overview of the central tenets of modern biology; (3) to afford experience in obtaining and interpreting biological hypotheses; and (4) to develop thinking and writing skills. Topics in Biology 162 are divided among four areas: (a) cellular and molecular biology; (b) genetics; (c) evolution; and (d) ecology. Students MUST: (1) attend 3 lectures, 1 one-and-a-half hour discussion, and 1 three hour lab section each week; (2) ATTEND THEIR ASSIGNED DISCUSSION AND LAB MEETINGS EACH WEEK STARTING WITH THURSDAY DISCUSSIONS IN THE FIRST WEEK OR THEIR SPACE MAY BE GIVEN TO SOMEONE ON THE WAITING LIST; and (3) RESERVE the times and dates for the midterm and final exams (as specified in the Time Schedule) before enrolling. Students usually purchase a textbook, lab manual, and course pack consisting of a syllabus and lecture notes. No other study guides or supplementary materials need be bought. For Honors credit, register for one of the Honors discussion/lab sections. For further information contact the Introductory Biology office, 1039 Chemistry Building (764-1430).

Check Times, Location, and Availability Cost: 3 Waitlist Code: 1

Biol. 195. Introduction to Biology.

Instructor(s): Hiroshi Ikuma (hikuma@umich.edu)

Prerequisites & Distribution: Three science or mathematics courses, including Chem. 130. Biol. 195 may be substituted wherever Biol. 152-154 (or the equivalent) is a prerequisite. No credit granted to those who have completed or are enrolled in Biol. 152-154 (or the equivalent). Credit is granted for a combined total of 12 credits elected in introductory biology. (6). (NS). (BS). Laboratory fee ($45) required.

Credits: (6).

Lab Fee: Laboratory fee ($45) required.

Course Homepage: http://www.biology.lsa.umich.edu/courses/bio195/main.html

Biology 195 is a one-term alternative to the Biology 152-154 sequence. It differs from 152-154 in the accelerated pace of study and emphasis on the laboratory. Students who enroll in the course should be aware of the intense nature of the course and the need for self-discipline and effective writing skills. Biology 195 is divided into four units (Biology of Cells, Genetics and Development, Biology of Organisms, and Biology of Populations). Unit examinations test both factual recall and analytical and integrative abilities. Lectures in Biology 195 reinforce key topics from the reading assignments and laboratory work and provide in-depth perspectives in several subdisciplines of biology. The laboratory, which is central to the course, provides the opportunity to make observations and perform experiments; these are discussed weekly in recitations. The course grade is based on examinations, laboratory reports, quizzes, and the student's participation in the course. Students are required to purchase the textbook Campbell's Biology (2nd ed.), a course pack, a laboratory kit (at Chem Stores), and a quadrille notebook. For more information concerning the course or registration, call 763-0495. Attend both first lecture and first recitation. DO NOT CRISP INTO A SECTION YOU CANNOT ATTEND.

Check Times, Location, and Availability Cost: 3 Waitlist Code: 1

Biol. 200. Undergraduate Tutorial.

Prerequisites & Distribution: Permission of faculty member in biology. (2). (Excl). (INDEPENDENT). May be repeated for a total of six credits.

Credits: (2).

Course Homepage: No Homepage Submitted.

This course is intended for sophomores learning research and laboratory techniques, working under close supervision of a faculty member. It may also be used for directed readings at an appropriate level. It includes reading on a significant topic and regular consultation with the faculty member chosen to supervise the work. The required paper could be on the scientific literature in a broad field, on biological issues on which the student may want to do continuing work, or on the detailed results of research in a biological specialty. Conferences, seminars, readings, and assigned writings are used to develop critical perspectives on modern biological problems and to provide breadth and sense of historical continuity in biological thought.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: No Data Given.

Biol. 222. From Message to Mind: An Introduction to Neurobiology.

Anatomy, Physiology, and Development

Instructor(s): Bruce Oakley (boakley@umich.edu)

Prerequisites & Distribution: Biol. 152-154 or 195. (3). (Excl). (BS).

Credits: (3).

Course Homepage: No Homepage Submitted.

An introduction to molecular, cellular, and systems-level neurobiology. Topics include: (1) bioelectricity; (2) intercellular communication; (3) sensory transduction and processing; (4) motor function; (5) the neural basis of learning and selected regulatory behaviors; and (6) development of the brain and sensory systems. Students will be evaluated by exams and participation in discussion. There are three lecture hours and one discussion hour per week.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: No Data Given.

Biol. 255. Plant Biology: An Organismic Approach.

Biological Evolution and Diversity

Instructor(s): Michael Wynne (mwynne@umich.edu)

Prerequisites & Distribution: (5). (NS). (BS). Satisfies a Biology laboratory requirement. Laboratory fee ($60) required.

Credits: (5).

Lab Fee: Laboratory fee ($60) required.

Course Homepage: http://www.biology.lsa.umich.edu/courses/bio255/bio255.html

An introductory botany course covering a broad spectrum of topics including principles of plant systematics, evolution, growth, and development. The lectures and laboratories concentrate on a group-by-group treatment of plant diversity, ranging from algae and fungi through primitive vascular plants and culminating in flowering plants. The approach is an evolutionary perspective, treating plants as organisms and emphasizing the innovations and structural adaptations of the various plant groups as well as life history strategies. Such topics as pollination biology, plant speciation, and vegetational biomes are included. The course also includes plant growth and structure. Two field trips are scheduled. Two one-hour lectures and two three-hour labs per week. A total of three lecture tests and three laboratory tests will be scheduled. Text: Raven et al., Biology of Plants, 6th edition.

Check Times, Location, and Availability Cost: 2 Waitlist Code: 3

Biol. 275. Introduction to Plant Development.

Instructor(s): Larry Noodén (ldnum@umich.edu)

Prerequisites & Distribution: Biol. 154 or 195. (4). (NS). (BS). Satisfies a Biology laboratory requirement. Laboratory fee ($70) required.

Credits: (4).

Lab Fee: Laboratory fee ($70) required.

Course Homepage: http://www.biology.lsa.umich.edu/~ldnum/bio275/275home.html

For students interested in how plants grow, this course presents an integrated structural and functional approach to plant development. Topics studied include cell biology, molecular biology, and cellular mechanics of plant growth, organogenesis and differentiation with emphasis on controls, particularly hormonal and environmental. The course will provide a basis for understanding the natural history and some practical aspects of plant life including the anticipated advances in plant biotechnology. Students attend two one-hour lectures, a one-hour discussion session, and three hours of laboratory each week. The lab will provide experience with both whole plants and axenic tissue cultures.

Check Times, Location, and Availability Cost: 2 Waitlist Code: 3

Biol. 281. General Ecology.

Ecology and Population Biology

Instructor(s): George Estabrook (gfred@umich.edu)

Prerequisites & Distribution: Biol. 152 and 154 and a laboratory course in chemistry. (3). (NS). (BS).

Credits: (3).

Course Homepage: No Homepage Submitted.

The course introduces the basic concepts and principles of ecology as applied to the study of individuals, populations, and communities of both plants and animals. Course topics include the roles of physical and biotic factors influencing the distribution and abundance of organisms, the dynamics of population growth, species interactions including competition, predation, mutualism, the structure of ecological communities, ecological succession, and applications of ecology to problems of environment and resource management. Biology 281 is a suitable prerequisite for intermediate and advanced courses in ecology. There will be lectures, discussions, and computer simulations. Three exams will constitute the main basis of evaluation.

Check Times, Location, and Availability Cost: 2 Waitlist Code: No Data Given.

Biol. 300. Undergraduate Research.

Prerequisites & Distribution: Eight credits of biology and 3.0 grade point average in science; permission of faculty member in biology. (1-3). (Excl). (INDEPENDENT). May be repeated for a total of 9 credits.

Credits: (1-3).

Course Homepage: No Homepage Submitted.

Intended primarily for juniors, including Honors students, who wish to pursue independent research or study at an intermediate level in an area of biological science. The student may ask an appropriate faculty member in the Department of Biology to direct the research project and supervise related readings. The project may take the form of an investigation of new problems in the field or laboratory, a detailed investigation of primary sources (a literature survey), development of new procedures or programs, design of a classroom experiment, etc. A final paper is required and must be approved by the research advisor.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: No Data Given.

Biol. 301. Writing for Biologists.

Sections 002-011 may be elected ECB

Instructor(s): Robert Helling (helling@umich.edu)

Prerequisites & Distribution: Biol. 152-154 or 195, and English 125. (3). (Excl). (BS).

Upper-Level Writing

Credits: (3).

Course Homepage: No Homepage Submitted.

Biology 301 has been designed to help biology concentrators to improve their writing AS BIOLOGISTS. Competence in writing in biology requires critical evaluation of one's work. In order to encourage the development of critical thinking, students critique published work as well as write essays, reviews, and research reports. The heart of the course lies in the weekly interaction between staff and student through discussion both in class sections and one-on-one. A weekly lecture provides structure and continuity and allows consideration of other topics such as interviewing and resume writing, ethics in biology, and the nature of science and creativity.

Check Times, Location, and Availability Cost: 1 Waitlist Code: No Data Given.

Biol. 302. Teaching Experience for Undergraduates.

Prerequisites & Distribution: Permission of instructor. (1-3). (Excl). May not be included in any of the Biological Sciences concentration programs. (EXPERIENTIAL).

Credits: (1-3).

Course Homepage: No Homepage Submitted.

Undergraduates participating in this course are responsible for (1) aiding regularly assigned Teaching Assistants; (2) providing tutorial help for undergraduates enrolled in the course; (3) meeting regularly with discussion and laboratory sessions; and (4) participating with Teaching Assistants in instructional activities.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: No Data Given.

Biol. 305. Genetics.

Section 001 Exams Will Be Held Mondays, Feb. 15, Mar. 15, and Apr. 5, 6:00-8:00 P.M. Optional Films and Workshops: Mondays, Jan. 25; Feb. 8; Mar. 8 and 29; Apr. 19; from 6:00 8:00

Instructor(s): Wesley Brown (wbrown@umich.edu) , Steven Clark (clarks@umich.edu)

Prerequisites & Distribution: Biol. 152 or 195. Prior or concurrent enrollment in Biol. 310, 311, or Biol. Chem. 415, or Chem. 451. (4). (Excl). (BS).

Credits: (4).

Course Homepage: No Homepage Submitted.

Open to students concentrating in the natural sciences or intending to apply for graduate or professional study in basic or applied biology. This introduction to genetics includes the following sections: DNA and chromosomes; gene transmission in Eukaryotes; linkage and recombination; genes and enzymes, the genetic code, and mutation; recombinant DNA, RFLP mapping, the Human Genome Project; gene regulation, transposons; population genetics; and quantitative genetics. There are three hours of lecture each week and one discussion section directed by GSIs. The discussion sections expand on and review lecture material, and discuss problem assignments. Grading is based on three exams and a final covering lectures, discussions and reading assignments, and a five-page mini-term paper based on journal articles in a course pack. Exams include new problems that test applications of basic concepts and genetic techniques. A practice problem set is available and is covered in discussion sections or the Genetics Study Center. Two demonstrations of living material and genetic tools are given during the term. Films, workshop/review sessions, and the three "hour" exams are given Monday nights. A CSP section is available. Biology 304 (taught by S.L. Allen) is available for those with a special interest in Genetics, including Honors' students.

Check Times, Location, and Availability Cost: 3 Waitlist Code: No Data Given.

Biol. 306. Introductory Genetics Laboratory.

Molecular and Cellular Biology

Instructor(s): Santhadevi Jeyabalan (sjeyabal@umich.edu)

Prerequisites & Distribution: Prior or concurrent enrollment in Biol. 305. (3). (Excl). (BS). Satisfies a Biology laboratory requirement. Laboratory fee ($70) required.

Credits: (3).

Lab Fee: Laboratory fee ($70) required.

Course Homepage: No Homepage Submitted.

This course provides students with laboratory experience on basic genetic principles. Students will analyze patterns of inheritance, gene interaction, linkage relationship, and genetic mapping of unknown mutants of Drosophila through a series of genetic crosses. By using molecular techniques such as Polymerase Chain Reaction (PCR) and gel electrophoresis, mutations in Caenorhabditis elegans will be mapped to chromosomal locations. The experiments in microbial genetics include mapping by conjugation in E. coli, recombination analysis by transduction using bacteria and phage, and complementation tests on "his" mutants of yeast. Experiments in Human Population Genetics include calculating allelic frequencies of PTC tasting in the class. Students will also be doing DNA fingerprinting of a VNTR locus using their own squamous epithelial cells. One hour lecture on Mondays 1-2 PM and one three-hour lab are scheduled each week; additional 3-4 hours of lab time per week is expected at irregular times. Students are expected to write one formal lab report and to keep a complete and accurate record of all results and analyses in a bound lab notebook. There are two tests given during the term.

Check Times, Location, and Availability Cost: 1 Waitlist Code: 1

Biol. 307. Developmental Biology.

Molecular and Cellular Biology

Section 001 There Will Be Three Evening Exams: Mon., Feb. 1, Wed., Feb. 24, and Mon., March 29 from 8-10 P.M

Instructor(s): Ronald Ellis (ronellis@umich.edu) , John Kuwada (kuwada@umich.edu)

Prerequisites & Distribution: Biol. 305. (3). (Excl). (BS).

Credits: (3).

Course Homepage: http://www.biology.lsa.umich.edu/courses/bio307/Bio307.html

This course introduces students to the basic principles of developmental biology. We will emphasize the continuity of developmental processes by examining the temporal sequence of development from the fertilized egg to the adult, and by examining several levels of control from the selective expression of genetic information to the orchestrated generation of complex tissues and organs. We will cover basic developmental events such as production of sperm and eggs, fertilization, development of the early embryo, and genesis of organs. We will cover basic developmental processes such as nucleocytoplasmic interactions, induction, morphogenetic movements, cellular interactions, and morphogenesis. We will also evaluate the experimental basis for our understanding of developmental processes. Grades will be based on several exams and a final.

Check Times, Location, and Availability Cost: 4 Waitlist Code: 1

Biol. 308. Developmental Biology Laboratory.

Anatomy, Physiology, and Development

Instructor(s): Santhadevi Jeyabalan (sjeyabal@umich.edu)

Prerequisites & Distribution: Prior or concurrent enrollment in Biol. 307. (3). (Excl). (BS). Satisfies a Biology laboratory requirement. Laboratory fee ($45) required.

Credits: (3).

Lab Fee: Laboratory fee ($45) required.

Course Homepage: No Homepage Submitted.

This course provides students with the opportunity to study first hand the development of a number of live vertebrate and invertebrate embryos, specifically sea urchin, amphibian, and chick embryos. In addition to observation of normal embryogenesis, students perform several of the experimental analyses which have contributed to a basic understanding of developmental processes. Exercises focus on fertilization, developmental morphology, induction, determination and differentiation of various tissues, metamorphosis, and regeneration. In addition to one hour lecture and one scheduled three-hour laboratory session each week, students are expected to spend about three additional hours in the laboratory each week. Grades are based on three laboratory tests, a term paper, and lab notebook evaluation. Maintenance of a lab notebook for a complete and accurate record of observations and experimental results is required. There is a required lab manual.

Check Times, Location, and Availability Cost: 1 Waitlist Code: No Data Given.

Biol. 310. Introductory Biochemistry.

Section 001 Midterm Exam: Wednesday, Feb. 24, 6:00 9:00 PM

Instructor(s): Karen Ocorr (kocorr@umich.edu)

Prerequisites & Distribution: Biol. 152 or 195; and organic chemistry. No credit granted to those who have completed or are enrolled in Biol. 311, Biol. Chem. 415, or Chem 451. (4). (Excl). (BS).

Credits: (4).

Course Homepage: http://www.biology.lsa.umich.edu/~www/bio310/310home.html

Introductory Biochemistry is designed to be a general introduction to the chemistry of biological systems. This course will furnish basic information concerning the organization of chemical reactions in cells and will include information on the enzymes that catalyze these reactions as well as on the interactions between different metabolic pathways. Topics covered include: amino acid structure and nomenclature, protein structure and function, enzyme kinetics, nucleic acids, intermediary metabolism, photosynthesis, and regulation of metabolism. This is a lecture based course with discussion sections, the final grade is based on a midterm and final as well as performance in discussion sections.

Check Times, Location, and Availability Cost: 2 Waitlist Code: No Data Given.

Biol. 311. Introductory Biochemistry.

Section 001 Self-Paced, Personalized System of Instruction. Orientation Meeting Wed., Jan. 6, 6-7 P.M., N S Auditorium. Optional Lectures on Thursdays from 12-1, 4140 Nat Sci Midterm Exam Wed., Feb. 24, 6:00 9:00 P.M. Final Exam Thurs., April 22, 6:00-9:00 P.M

Instructor(s): Marcy Osgood (mosgood@umich.edu)

Prerequisites & Distribution: Biol. 152 or 195; and organic chemistry. No credit granted to those who have completed or are enrolled in Biol. 310, Biol. Chem. 415, or Chem 451. (4). (Excl). (BS).

Credits: (4).

Course Homepage: http://biology.lsa.umich.edu/courses/bio311/

This course is taught by a self-paced, personalized system of instruction. Students interact, according to their own schedules, with undergraduate TA's. The student takes both a written and an oral quiz for each of 12 units which is graded and evaluated by the TA. If mastery is attained, the student may proceed to the next unit. Grades are assigned according to the number of units successfully completed and performance on the midterm and final examinations. This system is designed to take into consideration different rates of individual learning as well as to eliminate competition among students. TA's are available approximately 75-80 hours/week.

Check Times, Location, and Availability Cost: 3 Waitlist Code: 1

Biol. 325. Principles of Animal Physiology: Lecture.

Instructor(s): Karen Ocorr (koccor@umich.edu), Paul Webb (pwebb@umich.edu)

Prerequisites & Distribution: Biol. 152-154 or 195, and a year of chemistry. No credit granted to those who have completed or are enrolled in Biol. 420. (3). (Excl). (BS).

Credits: (3).

Course Homepage: http://www.snre.umich.edu/~pwebb/325home.html

This course is an introduction to the physiological view of animals and emphasizes zoological rather than human aspects. The course uses evidence from different groups of organisms to identify the general principles of functional mechanisms. It also considers variations in these mechanisms as related to the requirements of the animals but does not attempt a phylogenetic survey. The course is intended for concentrators and pre-medical students in their sophomore, junior, or senior years. The subject matter includes metabolism and temperature regulation, nervous and endocrine system controls and integration, respiration and circulation, water and ion balance, excretion, digestion, reproduction, and immune system function. There are three one-hour lectures a week, three one-hour examinations, and a final exam. This course may NOT be elected by students who have already taken Biology 420.

Check Times, Location, and Availability Cost: 3 Waitlist Code: 1

Biol. 326. Animal Physiology Laboratory.

Prerequisites & Distribution: Concurrent enrollment in Biol. 325. Students who have taken or intend at a later date to take Biol. 325 will not be admitted to Biol. 326 without special permission. (2). (Excl). (BS). Satisfies a Biology laboratory requirement. Laboratory fee ($70) required.

Credits: (2).

Lab Fee: Laboratory fee ($70) required.

Course Homepage: http://www.snre.umich.edu/~pwebb/325home.html

These laboratory exercises deal (usually concurrently) with topics covered in the lecture. The laboratory meets for one four-hour session a week. Students working in small groups present material for each exercise, collate class data, and perform analyses. A term paper and oral presentation are required. Students should have had Biology 325 or be taking it concurrently. Students who intend at a later date to take Biology 325 will not be admitted to Biology 326 without special permission.

Check Times, Location, and Availability Cost: 2 Waitlist Code: 1

Biol. 341. Parasitology.

Biological Evolution and Diversity

Instructor(s): Barry OConnor (bmoc@umich.edu)

Prerequisites & Distribution: Biol. 152-154 or 195. (4). (Excl). (BS). Satisfies a Biology laboratory requirement. Laboratory fee ($30) required.

Credits: (4).

Lab Fee: Laboratory fee ($30) required.

Course Homepage: http://www.ummz.lsa.umich.edu/curators/bmoc/bio341/

This course concentrates on the biology of animal/animal interactions including parasitism, commensalism, and mutualism. The focus is primarily evolutionary and ecological, with emphasis on the origins and development of such associations. The organismal approach will be stressed in studies of Protozoa, various helminth groups and arthropods, with examples including parasites of medical and veterinary importance. Discussions of host-parasite interactions will include co-evolutionary perspectives as well as traditional approaches. No specific background other than introductory biology is required, although courses in ecology and evolutionary biology will be helpful. Students will be evaluated on the basis of two hour-exams, a lecture final, a term paper, laboratory quizzes and a practical examination. This course consists of three lectures and one lab weekly.

Check Times, Location, and Availability Cost: 3 Waitlist Code: No Data Given.

Biol. 390. Evolution.

Biological Evolution and Diversity

Instructor(s): David Mindell (mindell@umich.edu)

Prerequisites & Distribution: Biol. 152-154. (4). (Excl). (BS).

Credits: (4; 5 in the half-term in Ann Arbor; 5 at Biol. Station).

Course Homepage: No Homepage Submitted.

This is a comprehensive lecture and recitation section course covering the evolution of organisms. This includes critical examination of: the origin of evolutionary thought, evolution at the molecular level, genetic change among populations and higher taxa, natural selection, speciation, phylogenetic systematics, the fossil record, development, patterns of extinction, biogeography, coevolution, and human evolution. Weekly discussions will focus on primary literature. Two midterm tests and one cumulative final exam will test students' knowledge of lecture material. Writing assignment(s) based on readings from the primary scientific literature will be required.

Check Times, Location, and Availability Cost: 2 Waitlist Code: No Data Given.

Biol. 400. Advanced Research.

Prerequisites & Distribution: 12 credits of biology, 3.0 average in science, and permission of faculty member in biology. (1-3). (Excl). (INDEPENDENT). May be repeated for a total of 9 credits.

Credits: (1-3).

Course Homepage: No Homepage Submitted.

Intended for those engaged in original research at an advanced level. This course number is most frequently elected by senior Honors students who have completed Biology 300 and who are completing their research and writing their thesis. A final paper is required. (Refer to the description of Biology 300 for more information.)

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: No Data Given.

Biol. 401. Advanced Topics in Biology.

Section 001 Species and Speciation: The Nature of Species and How They Form

Instructor(s): Richard Alexander (rdalex@umich.edu)

Prerequisites & Distribution: Intended for senior concentrators. (3). (Excl). (BS). May be repeated for a total of six credits.

Credits: (3).

Course Homepage: http://www.ummz.lsa.umich.edu/seminars/b401.html

Speciation is the evolutionary divergence, or multiplication, of populations: it is the way in which phylogenies generate and the principal cause of biodiversity. This course explores the nature of species, the reasons for speciation, the ways and means of discerning when speciation is occurring, and the features of different kinds of organisms that affect rates of speciation. Involved are studies of: (1) how differences arise and are maintained in traits such as life cycles, habitat and host relations, and sexual signals; (2) genetic variation with habitat and geography; and (3) the action of natural, sexual, and social selection on all traits of organisms. Sessions will consist of lectures and discussions of the literature and logic of topics related to speciation, from Darwin to the present. We will examine such topics as character displacement, genetic drift and population bottlenecks, dispersal and founder effects, stable hybrid zones, parapatry, disruptive selection, inbreeding, sensory bias, the nature and significance of phenotypic plasticity, and cultural inheritance of sexual signals. Each student will be expected to adopt a specific group of organisms early in the course and review all that is known about speciation in that group, completing from this study a term paper designed for publication.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: No Data Given.

Biol. 401. Advanced Topics in Biology.

Section 002 Plant-Animal Interactions

Instructor(s): Beverly Rathcke (brathcke@umich.edu)

Prerequisites & Distribution: Intended for senior concentrators. (3). (Excl). (BS). May be repeated for a total of six credits.

Credits: (3).

Course Homepage: No Homepage Submitted.

This course covers basic concepts on the ecology and evolution of plant-animal interactions. Topics include herbivory, pathogen infection, seed predation and dispersal, pollination, and protection mutualisms. Background in ecology is required. There are lectures and discussions. Readings are from current literature. Grades are based on papers, oral presentations, and discussion participation.

Check Times, Location, and Availability Cost: 1 Waitlist Code: 1, 4

Biol. 401. Advanced Topics in Biology.

Section 003 Genomes and Genomics

Instructor(s): John Langmore (langmore@umich.edu)

Prerequisites & Distribution: Intended for senior concentrators. (3). (Excl). (BS). May be repeated for a total of six credits.

Credits: (3).

Course Homepage: No Homepage Submitted.

The life sciences are being revolutionized by genomics, the systematic study of organismal DNA. Genomics is redefining biology as an information science. The ultimate premise of genomics is that all heritable structures and functions of an organism will someday be determined by analysis of the DNA sequence. Genomics has already made significant improvements in disease diagnosis and treatment, drug discovery, and genetic manipulation, and has led many multinational pharmaceutical, agricultural, and chemical companies to redefine themselves as life science companies. This course will focus on the structure and dynamics of bacterial, plant and animal genomes, the experimental and computational methods used to study DNA, the use of sequence information in biology and medicine, and the ethical and legal questions of genomics. The course will mix lectures by Dr. Langmore and guest speakers, discussion, and reading of original literature and reviews.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: No Data Given.

Biol. 404. Genetics, Development, and Evolution.

Molecular and Cellular Biology

Instructor(s): Micheal Frohlich (mfroh@umich.edu)

Prerequisites & Distribution: Biol. 305 or 390. (3). (Excl). (BS).

Credits: (3).

Course Homepage: No Homepage Submitted.

The aim of this course is to synthesize concepts relating to development and evolution, using genetics as a foundation. The motivation is that most courses in biology consider phenomena at a single organizational scale (molecules, cells, organisms, populations, ecosystems, or taxa), whereas a complete understanding of evolution will require the ability to think comfortably at the various hierarchical levels. Lectures will be 90 minutes long. They will be based on the current literature, and will cover: paleontology and the shape of the tree of life; comparative embryology and classical developmental biology; the fundamentals of molecular genetics with particular attention to developmental regulatory mechanisms in model organisms; molecular systematics and the new field of genomic science; and the basics of population genetics and quantitative genetics. Assessment will involve a combination of participation in discussion, exams, and a term paper.

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Biol. 405. Molecular Basis of Development.

Molecular and Cellular Biology

Instructor(s): Rolf Bodmer (rolf@umich.edu)

Prerequisites & Distribution: Biol. 152-154 and 305. A course in molecular and developmental biology is helpful but not required. (3). (Excl). (BS).

Credits: (3).

Course Homepage: No Homepage Submitted.

In this course, we will explore the molecular basis of pattern formation during the development of various vertebrate and invertebrate model organisms. We will be concerned with the problem of how asymmetry and diversity is generated and propagated at the molecular level, particularly in terms of actions and interactions of gene functions. We will focus, for example, on the molecular mechanisms of specifying a body axis, a limb, a heart, an eye and other organs. Moreover, we will compare the evolutionary conservation of pattern and organ formation between vertebrate and invertebrate systems.

How experiments have been designed and how conclusions have been reached will be a major emphasis of this course. Students are expected to critiqually read and present primary research articles related to the lectured material. Evaluations are based on oral group presentations and active participation during class discussions.

Check Times, Location, and Availability Cost: 1 Waitlist Code: 1

Biol. 412. Teaching Biochemistry by the Keller Plan.

Instructor(s): Marcy Osgood (mosgood@umich.edu)

Prerequisites & Distribution: Biol. 311 and permission of instructor. (3). (Excl). This is a graded course. May not be included in any of the Biological Sciences concentration programs. (EXPERIENTIAL).

Credits: (3).

Course Homepage: http://www.biology.lsa.umich.edu/~www/bio311/proctor.shtml

Undergraduates who previously have taken an introductory biochemistry course act as TAs for Introductory Biochemistry (Biology 311). TAs meet with the instructor for a two-hour class each week for lectures, presentations, and discussions of teaching and biochemistry. TAs also prepare a report on a recent advance in biochemistry which they present to their peers and the instructor. The major roles of the TAs are to examine the students on their mastery of unit material and to help the students with explanations supplementary to the textbook. At the completion of an instructor-generated written quiz, the student and TA grade the quiz together. TAs learn considerable biochemistry by repeated teachings of unit materials and, in addition, profit from their experience as teachers and evaluators.

Check Times, Location, and Availability Cost: 1 Waitlist Code: 3

Biol. 413. Plant Molecular Biology Laboratory.

Molecular and Cellular Biology

Instructor(s): Eran Pichersky (lelx@umich.edu)

Prerequisites & Distribution: Biol. 310 or 311, or Biol. Chem. 415; and Biol. 305. (3). (Excl). (BS). Satisfies a Biology laboratory requirement. Laboratory fee ($70) required.

Credits: (3).

Lab Fee: Laboratory fee ($70) required.

Course Homepage: No Homepage Submitted.

This is a project lab in which students learn to identify and analyze plant genes and gene products using the latest techniques of molecular biology. Emphasis will be on genes encoding unique plant characteristics. Students will first isolate genes from DNA libraries of various plant species. They will then analyze the sequence of genes they have isolated by DNA sequencing, and will characterize their copy number and expression levels by various techniques such as Southern blots, Northern blots, etc. The genes will then be manipulated to produce the gene products (i.e., proteins) in a bacterial system.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: 1

Biol. 418. Endocrinology.

Anatomy, Physiology, and Development

Instructor(s): Robert Denver (rdenver@umich.edu)

Prerequisites & Distribution: Biol. 152-154 or 195; organic chemistry. (3). (Excl). (BS).

Credits: (3).

Course Homepage: http://www.biology.lsa.umich.edu/courses/bio418/bio418.htm

This course is a comparative study of animal endocrine functions with emphasis on the cellular origin and chemical nature of hormones, the cellular and molecular mechanisms of hormone action, general endocrine control mechanisms, the evolution of hormones and hormonal control and their physiological actions in animals. The course will concentrate on the endocrine systems of vertebrates; there will be limited treatment of human endocrinology. Instruction in Biology 418 assumes a basic familiarity with general and comparative physiology. Training in chemistry through organic is essential, and courses in biochemistry and cell and molecular biology are helpful.

Check Times, Location, and Availability Cost: 2 Waitlist Code: 1

Biol. 425/Anatomy 425. Systems Neurobiology.

Anatomy, Physiology, and Development

Instructor(s): Stephen Easter (sseaster@umich.edu)

Prerequisites & Distribution: Biol. 222, 325, or 422. (3). (Excl). (BS).

Credits: (3).

Course Homepage: http://www.biology.lsa.umich.edu/courses/bio425/bio425.htm

This course focuses on ensembles of nerve cells, both their interactions and their emergent properties. Vertebrate nervous systems provide the bulk of the subject matter, divided into four blocks: development, sensory systems (especially the visual system), motor systems, and simple behaviors. The class format is lecture, but the small enrollment allows for extensive discussion during the lectures. Reading material includes a textbook and original papers. Students are evaluated with two hour exams, three papers, and a final exam.

Students are expected to have an understanding of cellular and molecular neurobiology, essential to the consideration of nervous systems, which is ordinarily obtained in one of the prerequisites (Biology 222, 325, or 422). Biology 425 differs from Biology 222 in being restricted to systems; those students wishing to obtain a one-semester introduction to neurobiology should enroll in 222. Biology 425 and 422 treat their topics in more depth than is encountered in Biology 222, but at different levels. Biology 422 emphasizes molecular and intracellular mechanisms of neural function (the first part of Biology 222) and Biology 425 emphasizes the intercellular interactions and their emergent properties (the second part of 222).

Check Times, Location, and Availability Cost: 3 Waitlist Code: 1

Biol. 426. Molecular Endocrinology.

Molecular and Cellular Biology

Instructor(s): Cunming Duan (cduan@umich.edu)

Prerequisites & Distribution: Biol. 310, 311, or Biol. Chem. 415; and Biol. 325 or 418. (3). (Excl). (BS).

Credits: (3).

Course Homepage: http://www.biology.lsa.umich.edu/courses/bio426/intro.html

This course is designed to provide students with a comprehensive overview on the latest advances in our understanding of how hormones work at the molecular and cellular level in vertebrate systems including humans. This course is intended for advanced undergraduate students and beginning graduate students. The course will begin with an overview of the modern experimental approaches for a variety of questions pertaining to endocrinology. We will then examine selected topics, including the gene structure, expression and regulation of various hormones and their biosynthesis, post-translational modification and degradation, the actions of hormones on cellular proliferation, differentiation, and programmed cell death, and the underlying molecular mechanisms of these cellular actions. A portion of this course will be devoted to discussing specific topics (i.e. hormones and tumorgenesis, environmental endocrine disrupters etc.) and reading relevant research publications. Students are expected to have a basic familiarity with biochemistry and/or animal or cellular physiology. Courses in endocrinology and cell and molecular biology are helpful. Grades will be based on three examinations and the discussion section.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: 1

Biol. 427. Molecular Biology.

Molecular and Cellular Biology

Section 001 Midterm Exams Will Be Held Monday Evenings, Feb. 8, Mar. 15, and Apr. 19, 6-8 PM

Instructor(s): Robert Helling (helling@umich.edu) , Janine Maddock (maddock@umich.edu)

Prerequisites & Distribution: Biol. 305; and Biol. 310 or 311, or Biol. Chem. 415. (4). (Excl). (BS).

Credits: (4).

Course Homepage: No Homepage Submitted.

Comprehensive coverage of the general principles governing the structures, synthesis, and functions of DNA, RNA, and proteins in the context of the cell. Emphasizes understanding methods and interpretation of data. Topics include DNA replication and transposition, chromosome segregation, transcription and translation, the processing of macromolecules, signal transfer, and regulation at various levels. Three lectures per week are supplemented by a 1.5 hour discussion section. There will be two examinations during the term and a final.

Check Times, Location, and Availability Cost: 3 Waitlist Code: No Data Given.

Biol. 428. Cell Biology.

Molecular and Cellular Biology

Section 001 Midterm Exams Will Be Held Monday Evenings, Feb. 1, Feb. 22, and Mar. 22, 6-8 P.M

Instructor(s): James Bardwell (jbardwel@umich.edu)

Prerequisites & Distribution: Biol. 305; and Biol. 310 or 311, or Biol. Chem. 415. Students with credit for Biol. 320 must obtain permission of instructor. (4). (Excl). (BS).

Credits: (4).

Course Homepage: http://www.biology.lsa.umich.edu/~www/bio428/

Biology 428 is designed to provide students with a comprehensive overview of the biology of eukaryotes and prokaryotes at the cellular and molecular level. This course is intended for upper-level undergraduates and graduate students. The information is presented at a level that requires students to integrate information from their other biology, chemistry, and biochemistry courses. Topics include: cell structure and function; cell membranes; intracellular organelles and cytoskeleton; inter- and intra-cellular signaling; cell development and cell cycle. Students will be expected to integrate the scientific data presented in class as well as to read and interpret basic research drawn from the current scientific literature. Grades will be based on four exams and the discussion section.

Check Times, Location, and Availability Cost: 2 Waitlist Code: No Data Given.

Biol. 429. Laboratory in Cell and Molecular Biology.

Molecular and Cellular Biology

Instructor(s): Eric Mann (ericmann@umich.edu)

Prerequisites & Distribution: Biol. 427 or 428, or concurrent enrollment in Biol. 428. No credit granted to those who have completed or are enrolled in Biol. Chem. 416 or 516. (3). (Excl). (BS). Satisfies a Biology laboratory requirement. Laboratory fee ($70) required.

Credits: (3).

Lab Fee: Laboratory fee ($70) required.

Course Homepage: No Homepage Submitted.

The course consists of two lectures and one four hour laboratory session each week. Additional time outside of scheduled lab sessions may be required. The lectures introduce basic cell biology and virology, and give the background for techniques used in the laboratory. The laboratory sessions introduce microscopy and staining, electrophoresis and cell culture. Grades are based on two lecture exams and a lab grant proposal. The course can be used to satisfy requirements in the Cell and Molecular Biology concentration and Microbiology concentration. It is also appropriate for the Biology concentration.

Check Times, Location, and Availability Cost: 2 Waitlist Code: 4

Biol. 430. Molecular Biology of Plants.

Molecular and Cellular Biology

Instructor(s): Charles Yocum (cyocum@umich.edu)

Prerequisites & Distribution: Biol. 305; and 310 or 311, or Biol. Chem. 415. (3). (Excl). (BS).

Credits: (3).

Course Homepage: No Homepage Submitted.

The topic of this course is major advances in understanding molecular processes in plants, and the contribution of molecular biological techniques to these advances. The course is intended for advanced undergraduates and beginning graduate students. The course will begin with an overview of the basic techniques of plant molecular biology such as cloning and sequencing of DNA, transformation, and analysis of gene expression. We will then examine selected topics in detail, including proteins, biochemical pathways, photoreception, photosynthesis, and respiration. We will read and then discuss research publications in class. Student performance will be evaluated on the basis of class participation, two take-home examinations, and a term paper.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: 1

Biol. 445/Geology 445. Biogeography.

Section 001.

Instructor(s): Gerald Smith (grsmith@umich.edu)

Prerequisites & Distribution: Biol. 152-154 or 195. Historical Geology (or equivalent) is recommended. (3). (Excl). (BS).

No Description Provided.

Check Times, Location, and Availability


Biol. 450. Biology of Amphibians and Reptiles.

Biological Evolution and Diversity

Instructor(s): Ronald Nussbaum (nuss@umich.edu)

Prerequisites & Distribution: Biol. 152-154 or 195. (5). (Excl). (BS). Satisfies a Biology laboratory requirement. Laboratory fee ($70) required.

Credits: (5).

Lab Fee: Laboratory fee ($70) required.

Course Homepage: http://biology.lsa.umich.edu/courses/bio450/

Lectures on the evolution, behavior, ecology, and life history of amphibians and reptiles. Laboratory exercises and field trips emphasize identification, life history, adaptations, and field methods.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: 1

Biol. 483. Limnology: Freshwater Ecology.

Ecology and Population Biology

Instructor(s): George Kling (gwk@umich.edu)

Prerequisites & Distribution: Advanced undergraduate or graduate standing, with background in physics, chemistry, biology, or water-related sciences. (3). (Excl). (BS). (QR/1).

Full QR

Credits: (3).

Course Homepage: http://biology.lsa.umich.edu/~gwk/b483syl.htm

Limnology is the study of lakes. Some of the topics covered in this course are: the origin of lakes; the importance of physical and chemical properties; the geochemical cycling of carbon, phosphorous, nitrogen, iron, and silicon; the ecology of aquatic bacteria, phytoplankton, zooplankton, benthos, macrophytes and fish; the pollution and eutrophication of lakes; paleolimnology; food-chain dynamics; energy-flow; and experimental investigations using whole lakes. Lectures are designed to provide the student with a basic understanding of limnology in addition to presenting up to date information from the current literature. Grades are based on examinations (no term paper). (No text, only a course guide). This course fulfills concentration requirements in the area of Ecology and Evolution. The limnology laboratory is offered as a separate course (Biology 484) described below.

Check Times, Location, and Availability Cost: 1 Waitlist Code: 1

Biol. 484. Limnology Laboratory.

Ecology and Population Biology

Instructor(s): George Kling (gwk@umich.edu)

Prerequisites & Distribution: Concurrent enrollment in Biol. 483. (3). (Excl). (BS). (QR/1). Satisfies a Biology laboratory requirement. Laboratory fee ($70) required.

Full QR

Credits: (3).

Lab Fee: Laboratory fee ($70) required.

Course Homepage: http://biology.lsa.umich.edu/~gwk/b484syl.htm

Field and laboratory techniques in aquatic science. The limnology laboratory is open to 12-15 students. Field trips to local lakes during both ice cover and open water conditions will enable students to master sampling and measurement techniques for acquiring physical, chemical, and biological data. Laboratory work will include chemical analysis of lake water, taxonomy and counting methods for aquatic biota, use of automated data acquisition technology, and experimental methods applicable to lake communities. In Winter Term 99, this course will offer an enhanced ability to accommodate student research projects.

Check Times, Location, and Availability Cost: 2 Waitlist Code: 1

Biol. 487/NR&E 409. Ecology of Fishes.

Ecology and Population Biology

Section 001 3 Credit Hours for Lecture only. 4 Credit Hours for Lecture and one Lab

Instructor(s): James Diana (jimd@umich.edu)

Prerequisites & Distribution: One course in ecology. (Lectures: 3 credits; lectures and lab: 4 credits). (Excl). (BS).

Credits: (Lectures: 3 credits; lectures and lab: 4 credits).

Course Homepage: http://www.umich.edu/~nre409/

Ecology is the study of interactions which determine the distribution and abundance of organisms. For fishes, these interactions can roughly be categorized into physiological, behavioral, and population-community interactions. Ecology of fishes is organized to examine all of these interactions. Although fishes are emphasized, other aquatic organisms are also included. Also, aquatic ecosystems of interest include not only local freshwater systems, but also tropical and marine ones. The course gives special emphasis on bioenergetics of fish, and how energy flow is viewed on an individual, population, and community level of organization. The course consists of 3 hours of lecture per week (for 3 credit hours). There is also an optional lab (3 hours per week) for one more credit hour. The lab emphasizes field ecology of fishes, as well as laboratory analyses of energetics and behavior. Evaluation of students is based on two midterm exams and a final exam, which emphasize essay questions involving synthesis. The lab is evaluated on a lab notebook and an exam. Reading materials include a textbook (estimated cost $45) and a small course pack (estimated cost $10).

Check Times, Location, and Availability Cost: 2 Waitlist Code: 1

Biol. 488. Microbial Ecology of Terrestrial Ecosystems.

Ecology and Population Biology

Instructor(s): Robert Fogel (rfogel@umich.edu)

Prerequisites & Distribution: Biol. 152. (3). (Excl). (BS).

Credits: (3).

Course Homepage: http://www.herb.lsa.umich.edu/Bio488/488_indx.htm

Biotechnology has brought new recognition to these fascinating and unique organisms. This lecture course surveys the members of the soil biota (bacteria, fungi, insects, and other invertebrates), provides an introduction to their ecology, structure and function of terrestrial ecosystems, and importance to man in biotechnology, maintaining and restoring ecosystem productivity, and plant pathology. This course provides useful training for students interested in careers in biotechnology, plant pathology, forest pathology, soil biology, and microbial ecology. Grades are based on three hourly exams and a project.

Check Times, Location, and Availability Cost: 2 Waitlist Code: 3

Biol. 491. Principles of Phylogenetic Systematics.

Biological Evolution and Diversity

Instructor(s): Arnold Kluge (akluge@umich.edu)

Prerequisites & Distribution: Biol. 152-154 or 195. (4). (Excl). (BS). Satisfies a Biology laboratory requirement.

Credits: (4).

Course Homepage: http://biology.lsa.umich.edu/courses/bio491/

Biology 491 focuses on cladistics, the most widely accepted approach used to discover species history. All aspects of phylogenetic inference the philosophical, theoretical, and methodological are reviewed in lecture. Major topics include parsimony, species concepts and speciation, monophyletic taxonomy, vicariance biogeography and conservation, adaptation, and coevolution. In the laboratory-discussion section of the course, relevant microcomputer algorithms are used to test hypotheses from the original literature. There are three essay (take-home) examinations, five laboratory exercises, a term paper, and an oral presentation of the term paper topic. There is no required text; however, all of the many handouts and the original literature that is reviewed constitute the required course pack.

Check Times, Location, and Availability Cost: 1 Waitlist Code: No Data Given.

Biol. 492. Behavioral Ecology.

Ecology and Population Biology

Instructor(s): Brian Hazlett (bhazlett@umich.edu)

Prerequisites & Distribution: Biol. 152-154 or 195, and one additional course in zoology. (4). (Excl). (BS).

Credits: (4 in Ann Arbor; 5 in the half-term; 5 at Biol. Station, which also includes Biology 493).

Course Homepage: No Homepage Submitted.

The objective of this course is to acquaint students with the subject of animal behavior. All types of behavior and their ecological ramifications are considered; both vertebrate and invertebrate examples are utilized. The course approaches behavior from a zoological viewpoint; emphasis is placed on understanding the methods of investigation used in the study of animal behavior. Consideration of physiological mechanisms is given, as well as discussion of the evolutionary framework in which behavior patterns evolve. The course is divided into two sections. In the first, the types of factors which affect behavior are discussed. During the second part of the course, functional categories of behavior (feeding, orientation, agonistic, sexual) are discussed with an emphasis on bringing together as many factors as possible in an attempt to understand the control (both proximate and ultimate) of these behaviors at all levels. Although Biology 152-154 or equivalent are required, it would be best to have at least one of the following three areas before taking the course: genetics, ecology, or neurophysiology. Students who wish to obtain a more complete background should plan to take Biology 422 and/or Biology 494 either before or after taking Biology 492. Methods of instruction: (1) lectures and discussion are the primary means of instruction; (2) a text is also utilized, as are a number of outside readings; (3) there is a midterm lecture exam and a short term paper, as well as a final exam.

Check Times, Location, and Availability Cost: 2 Waitlist Code: No Data Given.

Biol. 496/NR&E 425. Population Ecology.

Ecology and Population Biology

Instructor(s): Alvin Jensen (ajensen@umich.edu)

Prerequisites & Distribution: General ecology and NR&E 438; calculus recommended. (4). (Excl). (BS). Satisfies a Biology laboratory requirement.

Credits: (4).

Course Homepage: No Homepage Submitted.

The study of the dynamics of single species populations and systems of multi-species populations is examined. This is accomplished by reviewing the theoretical explanations for various topics and comparing these predictions with observations and experiments with animal and plant populations. Topics covered include population growth and its limiting factors (resource acquisition, life history patterns, habitat use, and social structure), competition, predation, population cycles, food web structure, and the stability and persistence of assemblages of populations. Because the theoretical development of these topics depends upon mathematics, students will find experiences with introductory calculus useful, and basic statistical knowledge is useful in understanding the comparison of observed plant and animal populations with the theoretical predictions. The course consists of two 90-minute lectures, a lab experiment requiring one hour and a discussion group for one-two hours each week. Students are evaluated on the basis of two hourly exams, a term paper, weekly short lab reports and participation in the discussion group.

Check Times, Location, and Availability Cost: 2 Waitlist Code: 3

Biol. 497. Community Ecology.

Ecology and Population Biology

Instructor(s): Deborah Goldberg (degold@umich.edu) , Earl Werner (eewerner@umich.edu)

Prerequisites & Distribution: A course in ecology. (3). (Excl). (BS).

Credits: (3).

Course Homepage: No Homepage Submitted.

An examination of current theory and empirical research on ecological communities. Emphasis is on the analyses of patterns in community structure and species diversity, and the mechanisms responsible for generating and maintaining these patterns. Specific topics include the roles of species interactions such as competition, predation, and mutualisms, environmental variation, and biogeography in community processes. A background in ecology is required. Readings are from the original literature. There are two one-hour lectures and one two-hour discussion per week.

Check Times, Location, and Availability Cost: 1 Waitlist Code: No Data Given.

Biol. 526/Chem. 526. Chemical Biology II.

Prerequisites & Distribution: Chemistry 525. Prior or concurrent enrollment in Chemistry 402 or equivalent. (3). (Excl). (BS).

Credits: (3).

Course Homepage: No Homepage Submitted.

This is the second of a two course sequence in Chemical Biology. The intent of these courses is to introduce students to the breadth of material contained within the inherently interdisciplinary "Chemical Biology" arena. The course has been designed to cross the traditional disciplinary boundaries of Chemistry. Thus, rather than having traditional bioorganic, bioinorganic, and biophysical sections, the course will focus on case studies chosen so that over the course of the two term sequence, all of the key concepts in the trditional chemical disciplines are discussed.

Check Times, Location, and Availability Cost: No Data Given. Waitlist Code: No Data Given.

Biol. 532. Birds of the World.

Biological Evolution and Diversity

Instructor(s): Robert Payne (rbpayne@umich.edu)

Prerequisites & Distribution: Sixteen credits of biology and permission of instructor. (4). (Excl). (BS).

Credits: (4).

Course Homepage: No Homepage Submitted.

This course is a comparative survey of avian systematics and the world avifauna. It provides systematic training in ornithology, particularly at the species and family level, and utilizes the research collections of birds (study skins and anatomical materials) of the Museum of Zoology. It highlights problems for research in the evolutionary systematics of birds. Testable objectives include an ability to identify birds to family or lower level and discuss their systematic relationships. Methods include lectures, demonstrations of avian diversity with the museum collections, bioacoustic analysis, library readings, and experience in independent research in systematic ornithology. Student evaluations are based on exams and papers.

Check Times, Location, and Availability Cost: 3 Waitlist Code: 3

Biol. 541/Anatomy 541/Physiology 541. Mammalian Reproductive Endocrinology.

Instructor(s): Douglas Foster (dlfoster@umich.edu)

Prerequisites & Distribution: Biol. 310 or 311, or Biol. Chem. 415. (4). (Excl). (BS).

Credits: (4).

Course Homepage: No Homepage Submitted.

The course provides an overview of the hormonal regulation of mammalian reproduction at the system, cellular, and molecular levels. Topics include basic and clinically-orientated material related to properties and mechanisms of action of the pituitary gonadotropic hormones and gonadal sex steroids, the neural control of reproduction, reproductive behavior, anatomy and endocrine regulation of the testis and ovary and of the male and female reproductive tracts, endocrine control of menstrual and estrous cycles, mechanisms of fertilization and implantation, and the endocrine basis of pregnancy and fertility regulation. Primarily for upper-level undergraduates or graduate students with a strong background in biology. Evaluation is by written examinations and presentation of a poster. The course is team-taught by several members of the multi-departmental Reproductive Sciences Program.

Check Times, Location, and Availability Cost: 2 Waitlist Code: 4

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