Nandakumar Lab

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A multi-pronged approach to understand how telomeres & telomerase participate in cancer, stem cell fitness, ageing, and genome stability


Kraus Natural Science Building
University of Michigan


We study telomeres and telomerase, which are protein-nucleic acid complexes that act on all eukaryotic chromosome ends. Telomeres ensure that our chromosome ends do not engage in illicit inter-chromosomal fusion events that could lead to various diseases including cancer. The RNA-protein enzyme telomerase on the other hand is required for continued proliferation of actively dividing cells such as stem cells and cancer cells. The lab’s research philosophy is to use a multi-pronged approach integrating structural, biochemical and cytological techniques that each feed into one another to develop a molecular model for how telomeres and telomerase perform their critical functions.

Primary Investigator

Contact Information

Nandakumar Lab
Department of Molecular, Cellular, and Developmental Biology (MCDB)
University of Michigan
4140 Kraus Natural Science Bldg.
830 North University Ave.
Ann Arbor, MI 48109
Lab Phone: TBD
Fax: 734-647-0884