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Assistant Professor, Biomedical Engineering
Office Location(s): 2170 LBME
Current Research Activity: It is not from lack of interest that the mechanical properties of such subcellular structures are in general poorly characterized. Until recently such measurements were generally not possible, and research to develop appropriate tools is ongoing. Our group develops and applies physical tools to study nanoscale biomechanics of mitosis and the cytoskeleton. Approaches include: optical tweezers to measure forces and manipulate subcellular structures; ultrafast pulsed lasers to ablate and machine structures that are smaller than the diffraction limit; and lithography techniques to pattern proteins and construct structures to control experimental geometry. We are applying these tools to determine the mechanical properties of cells that support motility and mophologic changes, especially during mitosis.
Chemistry BuildingRoom 4028930 N. University Ave.
Ann Arbor, MI