Controllability and Dynamics of the 3D Genome


Apr
08
2014

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  • Speaker: Indika Rajapakse, Assistant Professor, Dept. of Computational Medicine and Bioinformatics, U-M
  • Host Department: Center for the Study of Complex Systems
  • Date: 04/08/2014
  • Time: 12:00PM - 1:00PM

  • Location: 4448 East Hall

  • Description:

    The controllability of a dynamical system refers to the
    possibility of driving its state to a specific target state by means of a
    control input. Controllability of the dynamic 3D human genome will be
    discussed in the context of cellular reprogramming and for our work within
    the DARPA Biochronicity initiative that explores the genetic basis of
    biological time. I will more generally discuss the concept of "network
    controllability" and the potential impact of this work in other disciplines.

    Department of Computational Medicine and Bioinformatics
    Department of Mathematics, University of Michigan
    Biological Network Cluster