James Bardwell

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Rowena G. Matthews Collegiate Professor, MCDB
HHMI Investigator

830 N. University

Office Location(s): 4007A Nat. Sci.
Lab Address: 4007-08 Nat. Sci.
Lab Phone: 734.647.6683
Phone: 734.764.8028
Bardwell Lab Website
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  • Fields of Study
    • Catalysis of Protein Folding
  • About

    Proteins start life as linear amino acid sequences and end up as beautifully folded, active structures. Dr. Bardwell's laboratory focuses on recently discovered machinery that drives protein folding in the cell. Two types of folding helpers are being studied: the catalysts responsible for disulfide bond formation, and the heat shock proteins, which chaperone protein folding. Powerful genetic, structural, and biophysical tools are being used to generate a detailed picture of how these folding machines work.

    Dr. Bardwell received his Ph.D. from the University of Wisconsin at Madison in 1987 and was a postdoctoral fellow at Harvard Medical School. He has been a Fellow of the Alexander von Humboldt Foundation and held a Visiting Professor appointment in Regensburg, Germany.

  • Education
    • Ph.D., University of Wisconsin-Madison